STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
thrSthreonyl-tRNA synthetase; evidence=ISS; db_xref=cjejuni:Cj0206; date=20070321; method=automatic:reciprocal fasta; Belongs to the class-II aminoacyl-tRNA synthetase family. (603 aa)    
Predicted Functional Partners:
metS
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 0.907
infC
Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
 
  
 0.900
cysS
cysteinyl-tRNA synthetase; evidence=ISS; db_xref=cjejuni:Cj0802; date=20070321; method=automatic:reciprocal fasta; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.837
lysS
lysyl-tRNA synthetase; evidence=ISS; db_xref=cjejuni:Cj0401; date=20070321; method=automatic:reciprocal fasta; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 
 0.833
leuS
leucyl-tRNA synthetase; evidence=ISS; db_xref=cjejuni:Cj1091c; date=20070321; method=automatic:reciprocal fasta; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.823
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
 
 0.812
pheT
phenylalanyl-tRNA synthetase beta chain; evidence=ISS; db_xref=cjejuni:Cj0896c; date=20070321; method=automatic:reciprocal fasta; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
 
 0.809
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
 
 
 0.799
rpmA
50S ribosomal protein L27; evidence=ISS; db_xref=cjejuni:Cj0095; date=20070321; method=automatic:reciprocal fasta; Belongs to the bacterial ribosomal protein bL27 family.
   
 
 0.789
map
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
  
 
 
 0.768
Your Current Organism:
Helicobacter mustelae
NCBI taxonomy Id: 679897
Other names: H. mustelae 12198, Helicobacter mustelae 12198, Helicobacter mustelae str. 12198, Helicobacter mustelae strain 12198
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.