Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pthpeptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (184 aa)    
Predicted Functional Partners:
rplY
Ribosomal protein L25, ctc protein homolog; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
 
  
 0.920
ychF
Putative GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
 
  
 0.897
HMU08060
Putative integral membrane protein; evidence=ISS; db_xref=cjejuni:Cj0313; date=20070321; method=automatic:reciprocal fasta.
       0.814
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
  
 0.676
HMU08050
Putative oxidoreductase iron-sulfur subunit; evidence=ISS; db_xref=cjejuni:Cj0075c; date=20070321; method=automatic:reciprocal fasta.
  
    0.608
HMU08030
Putative hypothetical protein; evidence=ISS; db_xref=cjejuni:Cj0073c; date=20070321; method=automatic:reciprocal fasta.
       0.605
HMU08040
Putative iron-sulfur protein; evidence=ISS; db_xref=cjejuni:Cj0074c; date=20070321; method=automatic:reciprocal fasta.
       0.605
tilS
Putative tRNA(Ile)-lysidine synthase, TilS; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
  
  
 0.577
HMU09580
Putative PP-loop family protein; evidence=ISS; db_xref=cjejuni:Cj0118; date=20070321; method=automatic:reciprocal fasta; Belongs to the TtcA family.
  
  
 0.566
HMU08090
Putative S4 domain protein; evidence=ISS; db_xref=cjejuni:Cj0667; date=20070321; method=automatic:reciprocal fasta.
  
    0.551
Your Current Organism:
Helicobacter mustelae
NCBI taxonomy Id: 679897
Other names: H. mustelae 12198, Helicobacter mustelae 12198, Helicobacter mustelae str. 12198, Helicobacter mustelae strain 12198
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.