STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
carBCarbamoyl-phosphate synthase large chain; evidence=ISS; db_xref=cjejuni:Cj0279; date=20070321; method=automatic:reciprocal fasta; Belongs to the CarB family. (1086 aa)    
Predicted Functional Partners:
pyrB
Aspartate carbamoyltransferase; evidence=ISS; db_xref=cjejuni:Cj1098; date=20070321; method=automatic:reciprocal fasta; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 0.999
carA
Carbamoyl-phosphate synthase small chain; evidence=ISS; db_xref=cjejuni:Cj1494c; date=20070321; method=automatic:reciprocal fasta; Belongs to the CarA family.
 0.999
argG
Argininosuccinate synthase; evidence=ISS; db_xref=cjejuni:Cj0665c; date=20070321; method=automatic:reciprocal fasta; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
 
 0.993
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
 
 0.973
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 
 0.972
pyrC2
Putative dihydroorotase; evidence=ISS; db_xref=cjejuni:Cj1195c; date=20070321; method=automatic:reciprocal fasta.
 
 
 0.939
glmS
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
   
 0.935
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
  
 
 0.932
glnA
Glutamine synthetase; evidence=ISS; db_xref=cjejuni:Cj0699c; date=20070321; method=automatic:reciprocal fasta; Belongs to the glutamine synthetase family.
  
 
 0.932
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 
 0.931
Your Current Organism:
Helicobacter mustelae
NCBI taxonomy Id: 679897
Other names: H. mustelae 12198, Helicobacter mustelae 12198, Helicobacter mustelae str. 12198, Helicobacter mustelae strain 12198
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.