close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH61091.1DEAD/H associated domain protein; COGs: COG1201 Lhr-like helicase; InterProIPR002464:IPR014021:IPR001650:IPR014014:IPR 017170:IPR011545:IPR013701:IPR014001; KEGG: mac:MA0762 ATP-dependent DNA helicase; PFAM: DEAD/H associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Q8TSN3 ATP-dependent DNA helicase; PFAM: Helicase conserved C-terminal domain; DEAD/H associated; DEAD/DEAH box helicase. (951 aa)    
Predicted Functional Partners:
AEH61090.1
Metallophosphoesterase; COGs: COG1407 ICC-like phosphoesterase; InterPro IPR004843; KEGG: mma:MM_1914 hypothetical protein; PFAM: metallophosphoesterase; SPTR: Q8PVP8 Putative uncharacterized protein; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: putative phosphoesterase, SbcD/Mre11-related.
 
    0.894
AEH60136.1
AAA ATPase; COGs: COG1474 Cdc6-related protein AAA superfamily ATPase; InterPro IPR003593; KEGG: afu:AF0244 cell division control protein 6, putative; SMART: AAA ATPase; SPTR: O29995 Cell division control protein 6 homolog 1; PFAM: ATPase family associated with various cellular activities (AAA); CDC6, C terminal.
 
 
   0.543
dys
Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
 
     0.543
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
 
   
 0.539
AEH61092.1
Putative ferredoxin; InterPro IPR017896:IPR001080; KEGG: mma:MM_2984 putative ferredoxin; SPTR: Q8PSU2 Putative ferredoxin.
       0.529
AEH61089.1
KEGG: mma:MM_2884 hypothetical protein; SPTR: Q8PT34 Conserved protein.
       0.528
AEH59882.1
Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication.
 
 
   0.520
AEH61708.1
Transcriptional regulator, XRE family; COGs: COG1709 transcriptional regulator protein; InterPro IPR017271:IPR010982:IPR001387; KEGG: mbu:Mbur_1931 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Q12UR4 HTH DNA-binding domain protein; PFAM: Helix-turn-helix.
  
     0.518
AEH61350.1
Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication.
 
 
   0.516
dtdA
Protein of unknown function DUF516; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
 
 
   0.509
Your Current Organism:
Methanosalsum zhilinae
NCBI taxonomy Id: 679901
Other names: M. zhilinae DSM 4017, Methanosalsum zhilinae DSM 4017, Methanosalsum zhilinae str. DSM 4017, Methanosalsum zhilinae strain DSM 4017
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.