STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH61415.1KEGG: mba:Mbar_A0115 hypothetical protein; SPTR: Q46G90 Putative uncharacterized protein. (197 aa)    
Predicted Functional Partners:
ala
Alanine dehydrogenase; Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate; Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
       0.608
AEH61417.1
Protein of unknown function DUF434; COGs: COG2454 conserved hypothetical protein; InterPro IPR007368; KEGG: mma:MM_0098 hypothetical protein; PFAM: protein of unknown function DUF434; SPTR: Q8Q0N8 Conserved protein; PFAM: Protein of unknown function (DUF434).
       0.456
AEH61418.1
alpha-L-glutamate ligase, RimK family; COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); InterPro IPR011761:IPR013816:IPR013651:IPR004666; KEGG: mma:MM_0111 ribosomal protein S6 modification protein; PFAM: RimK domain protein ATP-grasp; SPTR: Q8Q0M5 Tetrahydromethanopterin:alpha-L-glutamate ligase; TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK-like ATP-grasp domain; TIGRFAM: alpha-L-glutamate ligases, RimK family.
       0.456
pth
Aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
       0.408
Your Current Organism:
Methanosalsum zhilinae
NCBI taxonomy Id: 679901
Other names: M. zhilinae DSM 4017, Methanosalsum zhilinae DSM 4017, Methanosalsum zhilinae str. DSM 4017, Methanosalsum zhilinae strain DSM 4017
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.