STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH61438.1COGs: COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductase; InterPro IPR006137:IPR006138; KEGG: mac:MA1496 F(420)H(2) dehydrogenase, subunit FpoB; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: Q8TQP4 F(420)H(2) dehydrogenase, subunit FpoB; TIGRFAM: NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, B subunit; Belongs to the complex I 20 kDa subunit family. (189 aa)    
Predicted Functional Partners:
AEH60888.1
NADH/Ubiquinone/plastoquinone (complex I); COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR001516:IPR001750:IPR003916; KEGG: mbu:Mbur_0132 putative monovalent cation/H+ antiporter subunit A; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; SPTR: Q12ZH7 Na+/H+ antiporter subunit; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus.
  
 
 0.999
AEH61428.1
Proton-translocating NADH-quinone oxidoreductase, chain N; COGs: COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N); InterPro IPR001750:IPR010096:IPR003916; KEGG: mbu:Mbur_1287 F420H2 dehydrogenase subunit N; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: Q466B8 F420H2 dehydrogenase subunit N; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N.
 
 0.999
AEH61429.1
Proton-translocating NADH-quinone oxidoreductase, chain M; COGs: COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); InterPro IPR001750:IPR010227:IPR003918; KEGG: mbu:Mbur_1288 F420H2 dehydrogenase subunit M; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: Q12WG9 F420H2 dehydrogenase subunit M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-ubiquinone oxidoreductase chain 4, amino terminus; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M.
 
 0.999
AEH61431.1
COGs: COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K); InterPro IPR001133; KEGG: mbu:Mbur_1290 F420H2 dehydrogenase subunit K; PFAM: NADH-ubiquinone oxidoreductase chain 4L; SPTR: Q12WG7 F420H2 dehydrogenase subunit K; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L.
 
 
 0.999
AEH61434.1
4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); InterPro IPR017896:IPR017900:IPR001450:IPR009051; KEGG: mbu:Mbur_1292 F420H2 dehydrogenase subunit I; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q12WG6 F420H2 dehydrogenase subunit I; PFAM: 4Fe-4S binding domain.
 
 0.999
fpoH
NADH dehydrogenase (quinone); FPO shuttles electrons from F(420)H(2), via FAD and iron- sulfur (Fe-S) centers, to quinones in the F(420)H(2):heterodisulfide oxidoreduction chain. The immediate electron acceptor for the enzyme in this species is believed to be methanophenazine. Couples the redox reaction to proton translocation (for every two electrons transferred, 0.9 hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
 
 0.999
AEH61436.1
NADH dehydrogenase (quinone); COGs: COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7; InterPro IPR001135; KEGG: mba:Mbar_A3409 F420H2 dehydrogenase subunit D; PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; PRIAM: NADH dehydrogenase (quinone); SPTR: Q8TQP2 F(420)H(2) dehydrogenase, subunit FpoD; PFAM: Respiratory-chain NADH dehydrogenase, 49 Kd subunit.
 0.999
AEH61437.1
COGs: COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit; InterPro IPR001268:IPR020396:IPR010218; KEGG: mba:Mbar_A3410 NADH dehydrogenase subunit C; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; SPTR: Q466A9 F420H2 dehydrogenase subunit C; TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C.
 
 0.999
AEH61439.1
COGs: COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A); InterPro IPR000440; KEGG: mma:MM_2491 F420H2 dehydrogenase subunit; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 3; SPTR: Q8TQP5 F(420)H(2) dehydrogenase, subunit FpoA; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3.
 
 0.999
AEH61430.1
Proton-translocating NADH-quinone oxidoreductase, chain L; COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterProIPR001516:IPR001750:IPR003945:IPR003916:IPR 018393; KEGG: mac:MA1504 F(420)H(2) dehydrogenase, subunit FpoL; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; PRIAM: NADH dehydrogenase (quinone); SPTR: Q8TQN6 F(420)H(2) dehydrogenase, subunit FpoL; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone oxidored [...]
 
 
 0.992
Your Current Organism:
Methanosalsum zhilinae
NCBI taxonomy Id: 679901
Other names: M. zhilinae DSM 4017, Methanosalsum zhilinae DSM 4017, Methanosalsum zhilinae str. DSM 4017, Methanosalsum zhilinae strain DSM 4017
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