STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
cobDCobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (309 aa)    
Predicted Functional Partners:
Mpet_0148
Protein of unknown function DUF105; COGs: COG1865 conserved hypothetical protein; InterPro IPR002808:IPR007212; KEGG: mla:Mlab_0705 hypothetical protein; PFAM: protein of unknown function DUF105; cysteine-rich small domain; SPTR: Putative uncharacterized protein; PFAM: Cysteine-rich small domain; Adenosylcobinamide amidohydrolase.
 
  
 0.991
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
 
 0.990
Mpet_2294
COGs: COG2109 ATP:corrinoid adenosyltransferase; InterPro IPR003724; KEGG: mhu:Mhun_0284 cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PRIAM: Cob(I)yrinic acid a,c-diamide adenosyltransferase; SPTR: Cob(I)yrinic acid a,c-diamide adenosyltransferase; TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; TIGRFAM: cob(I)alamin adenosyltransferase.
 
  
 0.973
Mpet_1297
Aminotransferase class I and II; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839; KEGG: mla:Mlab_0745 aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase.
 
  
 0.956
Mpet_1759
Precorrin-8X methylmutase CbiC/CobH; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: mla:Mlab_1081 precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase CbiC/CobH; SPTR: Precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase.
 
  
 0.950
Mpet_1298
COGs: COG2266 GTP:adenosylcobinamide-phosphate guanylyltransferase; KEGG: mem:Memar_1446 5-deoxyadenosylcobinamide phosphate nucleotidyltransferase; SPTR: Molybdenum cofactor guanylyltransferase; TIGRFAM: conserved hypothetical protein TIGR00454.
 
  
  0.941
Mpet_2230
Protein of unknown function DUF105; COGs: COG1865 conserved hypothetical protein; InterPro IPR002808; KEGG: mbu:Mbur_1001 hypothetical protein; PFAM: protein of unknown function DUF105; SPTR: Adenosylcobinamide amidohydrolase; PFAM: Adenosylcobinamide amidohydrolase.
 
  
 0.935
cbiD
Cobalamin (vitamin B12) biosynthesis CbiD protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.920
Mpet_0008
Protein of unknown function DUF343; InterPro IPR005651; KEGG: mem:Memar_0006 hypothetical protein; PFAM: protein of unknown function DUF343; SPTR: Putative uncharacterized protein; PFAM: Trm112p-like protein.
       0.874
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.872
Your Current Organism:
Methanolacinia petrolearia
NCBI taxonomy Id: 679926
Other names: M. petrolearia DSM 11571, Methanolacinia petrolearia DSM 11571, Methanoplanus petrolearius DSM 11571, Methanoplanus petrolearius SEBR 4847
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