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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mpet_1908Methanogenesis marker protein 15; COGs: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); InterPro IPR017676:IPR008275:IPR002731; KEGG: mem:Memar_2061 putative CoA-substrate-specific enzyme activase; PFAM: ATPase BadF/BadG/BcrA/BcrD type; SPTR: Putative CoA-substrate-specific enzyme activase; TIGRFAM: methanogenesis marker protein 15; CoA-substrate-specific enzyme activase; PFAM: BadF/BadG/BcrA/BcrD ATPase family; TIGRFAM: CoA-substrate-specific enzyme activase, putative; putative methanogenesis marker protein 15. (413 aa)    
Predicted Functional Partners:
Mpet_1907
COGs: COG4050 conserved hypothetical protein; InterPro IPR012356; KEGG: mem:Memar_2062 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: methanogenesis marker protein 5; PFAM: Uncharacterized protein conserved in archaea (DUF2112); TIGRFAM: putative methanogenesis marker protein 5.
 
    0.981
Mpet_1910
Methanogenesis marker protein 7; COGs: COG4052 Uncharacterized protein related to methyl coenzyme M reductase subunit C; InterPro IPR011312; KEGG: mem:Memar_2059 hypothetical protein; PFAM: Protein of unknown function UCP019164; SPTR: Putative uncharacterized protein; TIGRFAM: methanogenesis marker protein 7; PFAM: Methyl-coenzyme M reductase operon protein C; TIGRFAM: putative methanogenesis marker protein 7.
 
     0.979
Mpet_1906
Methanogenesis marker protein 6; COGs: COG4029 conserved hypothetical protein; InterPro IPR012025; KEGG: mem:Memar_2063 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: methanogenesis marker protein 6; PFAM: Uncharacterized protein conserved in archaea (DUF2102); TIGRFAM: putative methanogenesis marker protein 6.
 
     0.977
Mpet_1904
Methyl coenzyme M reductase system, component A2; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR017669:IPR003593:IPR003439:IPR017871; KEGG: mem:Memar_2065 ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter-related protein; TIGRFAM: methyl coenzyme M reductase system, component A2; PFAM: ABC transporter; TIGRFAM: methyl coenzyme M reductase system, component A2.
 
     0.974
Mpet_1905
Methanogenesis marker protein 3; COGs: COG4070 peptidyl-prolyl cis-trans isomerase (rotamase) cyclophilin family; InterPro IPR016466; KEGG: mbn:Mboo_2435 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: methanogenesis marker protein 3; TIGRFAM: putative methanogenesis marker protein 3; Belongs to the UPF0288 family.
 
     0.974
Mpet_1909
Methanogenesis marker protein 17; COGs: COG4051 conserved hypothetical protein; InterPro IPR016762; KEGG: mem:Memar_2060 hypothetical protein; PFAM: Uncharacterised conserved protein UCP019464, methanogenesis; SPTR: Putative uncharacterized protein; TIGRFAM: methanogenesis marker protein 17; PFAM: Uncharacterized protein conserved in archaea (DUF2113); TIGRFAM: putative methanogenesis marker protein 17.
 
     0.974
Mpet_2417
COGs: COG4056 Methyl coenzyme M reductase subunit C; InterPro IPR007687; KEGG: mbn:Mboo_0584 methyl-coenzyme M reductase operon protein C; PFAM: Methyl-coenzyme M reductase protein C; SPTR: Methyl-coenzyme M reductase operon protein C; TIGRFAM: methyl-coenzyme M reductase I operon protein C; PFAM: Methyl-coenzyme M reductase operon protein C; TIGRFAM: methyl-coenzyme M reductase I operon protein C.
 
     0.759
Mpet_1991
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
     0.745
Mpet_1993
COGs: COG4054 Methyl coenzyme M reductase beta subunit; InterPro IPR003179; KEGG: mem:Memar_0375 methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit; PRIAM: Coenzyme-B sulfoethylthiotransferase; SPTR: Methyl-coenzyme M reductase, beta subunit; TIGRFAM: methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase beta subunit, C-terminal domain; Methyl-coenzyme M reductase beta subunit, N-terminal domain; TIGRFAM: methyl-coenzyme M reductase, beta subunit.
 
     0.745
Mpet_2415
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
     0.745
Your Current Organism:
Methanolacinia petrolearia
NCBI taxonomy Id: 679926
Other names: M. petrolearia DSM 11571, Methanolacinia petrolearia DSM 11571, Methanoplanus petrolearius DSM 11571, Methanoplanus petrolearius SEBR 4847
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