STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mpet_1922methylated-DNA/protein- cysteinemethyltransferase; COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR014048:IPR001497; KEGG: mem:Memar_0790 methylated-DNA--protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; SPTR: Methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase. (159 aa)    
Predicted Functional Partners:
Mpet_1921
DEAD_2 domain protein; COGs: COG1199 Rad3-related DNA helicase; InterPro IPR006554:IPR006555:IPR010614:IPR014013; KEGG: mem:Memar_0789 helicase C2; PFAM: DEAD_2 domain protein; SMART: helicase c2; Helicase-like, DEXD box c2 type; SPTR: Helicase c2; PFAM: DEAD_2.
     
 0.931
Mpet_1923
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
       0.844
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
     
 0.827
rlmH
Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
       0.744
dtdA
Protein of unknown function DUF516; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
       0.672
Mpet_2250
KEGG: mem:Memar_0826 UspA domain-containing protein; SPTR: UspA domain protein; PFAM: Universal stress protein family.
 
    0.664
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.619
Mpet_0179
UspA domain protein; COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006015:IPR006016; KEGG: mhu:Mhun_0542 hypothetical protein; PFAM: UspA domain protein; SPTR: UspA; PFAM: Universal stress protein family.
  
    0.615
Mpet_0562
UspA domain protein; COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016:IPR006015; KEGG: mpl:Mpal_0780 UspA domain protein; PFAM: UspA domain protein; SPTR: UspA domain protein; PFAM: Universal stress protein family.
  
    0.615
Mpet_0574
UspA domain protein; COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016:IPR006015; KEGG: mbn:Mboo_2196 UspA domain-containing protein; PFAM: UspA domain protein; SPTR: UspA domain protein; PFAM: Universal stress protein family.
  
    0.615
Your Current Organism:
Methanolacinia petrolearia
NCBI taxonomy Id: 679926
Other names: M. petrolearia DSM 11571, Methanolacinia petrolearia DSM 11571, Methanoplanus petrolearius DSM 11571, Methanoplanus petrolearius SEBR 4847
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