Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rlmHProtein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. (161 aa)    
Predicted Functional Partners:
Mpet_1921
DEAD_2 domain protein; COGs: COG1199 Rad3-related DNA helicase; InterPro IPR006554:IPR006555:IPR010614:IPR014013; KEGG: mem:Memar_0789 helicase C2; PFAM: DEAD_2 domain protein; SMART: helicase c2; Helicase-like, DEXD box c2 type; SPTR: Helicase c2; PFAM: DEAD_2.
  
  
 0.777
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
       0.773
Mpet_1922
methylated-DNA/protein- cysteinemethyltransferase; COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR014048:IPR001497; KEGG: mem:Memar_0790 methylated-DNA--protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; SPTR: Methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase.
       0.741
Mpet_1923
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
       0.735
Mpet_2008
KEGG: mhu:Mhun_2509 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Transcription factor Pcc1.
   
    0.580
queE
Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
   
    0.554
Mpet_1920
Phage shock protein C, PspC; COGs: COG1983 Putative stress-responsive transcriptional regulator protein; InterPro IPR007168; KEGG: mhu:Mhun_2935 phage shock protein C, PspC; PFAM: PspC domain protein; SPTR: Phage shock protein C, PspC; PFAM: PspC domain.
       0.521
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
 
  
 0.453
Mpet_0998
Methanogenesis marker protein 9; COGs: COG4008 metal-binding transcription factor; InterPro IPR017671; KEGG: mem:Memar_1729 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: methanogenesis marker protein 9; TIGRFAM: TIM-barrel protein, putative; putative methanogenesis marker domain 9.
  
  
 0.440
Mpet_1919
COGs: COG0015 Adenylosuccinate lyase; InterProIPR004769:IPR000362:IPR003031:IPR019468:IPR 020557; KEGG: mem:Memar_0781 adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; SPTR: Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
 0.413
Your Current Organism:
Methanolacinia petrolearia
NCBI taxonomy Id: 679926
Other names: M. petrolearia DSM 11571, Methanolacinia petrolearia DSM 11571, Methanoplanus petrolearius DSM 11571, Methanoplanus petrolearius SEBR 4847
Server load: low (12%) [HD]