STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mpet_1990Protein of unknown function DUF2196; COGs: COG4895 conserved hypothetical protein; InterPro IPR019240; KEGG: mmx:MmarC6_0215 hypothetical protein; PFAM: Protein of unknown function DUF2196; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2196). (73 aa)    
Predicted Functional Partners:
Mpet_1991
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
       0.441
Mpet_1992
COGs: COG4057 Methyl coenzyme M reductase gamma subunit; InterPro IPR003178; KEGG: mem:Memar_0377 methyl-coenzyme M reductase, gamma subunit; PFAM: Methyl-coenzyme M reductase, gamma subunit; PRIAM: Coenzyme-B sulfoethylthiotransferase; SPTR: Methyl-coenzyme M reductase, gamma subunit; TIGRFAM: methyl-coenzyme M reductase, gamma subunit; PFAM: Methyl-coenzyme M reductase gamma subunit; TIGRFAM: methyl-coenzyme M reductase, gamma subunit.
       0.441
Mpet_1989
COGs: COG2236 phosphoribosyltransferase; InterPro IPR000836; KEGG: mtp:Mthe_0750 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain.
       0.405
Your Current Organism:
Methanolacinia petrolearia
NCBI taxonomy Id: 679926
Other names: M. petrolearia DSM 11571, Methanolacinia petrolearia DSM 11571, Methanoplanus petrolearius DSM 11571, Methanoplanus petrolearius SEBR 4847
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