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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Mpet_2007Phosphoesterase RecJ domain protein; COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR001667:IPR003156; KEGG: mem:Memar_0429 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase, RecJ domain protein; PFAM: DHHA1 domain; DHH family. (405 aa)    
Predicted Functional Partners:
Mpet_2008
KEGG: mhu:Mhun_2509 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Transcription factor Pcc1.
  
    0.933
Mpet_0947
Phosphoesterase RecJ domain protein; COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR001667:IPR003156; KEGG: mem:Memar_1684 phosphoesterase, DHHA1; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase, DHHA1; PFAM: DHHA1 domain; DHH family.
  
  
 
0.927
polB
DNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
  
 
 
 0.908
rps3ae
COGs: COG1890 Ribosomal protein S3AE; InterPro IPR001593; KEGG: mem:Memar_0427 30S ribosomal protein S3Ae; PFAM: ribosomal protein S3Ae; SPTR: 30S ribosomal protein S3Ae; PFAM: Ribosomal S3Ae family; Belongs to the eukaryotic ribosomal protein eS1 family.
       0.906
rps15
COGs: COG0184 Ribosomal protein S15P/S13E; InterPro IPR012606:IPR000589; KEGG: mhu:Mhun_2511 30S ribosomal protein S15P; PFAM: Ribosomal S13S15 domain protein; ribosomal protein S15; SPTR: 30S ribosomal protein S15P/S13e; PFAM: Ribosomal S13/S15 N-terminal domain; Ribosomal protein S15.
     
 0.881
Mpet_1774
KEGG: mpl:Mpal_0954 hypothetical protein; SPTR: Putative uncharacterized protein.
 
 
 
 0.844
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
 
 
 0.819
Mpet_0097
Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family.
 
   
 0.744
polC
DNA polymerase II, large subunit DP2; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.
 
   
 0.741
Mpet_2010
KEGG: mla:Mlab_0579 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.724
Your Current Organism:
Methanolacinia petrolearia
NCBI taxonomy Id: 679926
Other names: M. petrolearia DSM 11571, Methanolacinia petrolearia DSM 11571, Methanoplanus petrolearius DSM 11571, Methanoplanus petrolearius SEBR 4847
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