STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Alfi_0944Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (419 aa)    
Predicted Functional Partners:
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.938
coaX
Pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
  
 
 0.922
Alfi_0945
DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
    0.869
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 
 0.865
Alfi_2055
PFAM: Aminotransferase class I and II.
  
  0.829
Alfi_0943
Hypothetical protein.
 
    0.820
Alfi_3028
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; PFAM: Aminotransferase class I and II.
    
  0.803
Alfi_3249
O-acetylhomoserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase.
     
  0.800
Alfi_0942
Beta-barrel assembly machine subunit BamD; TIGRFAM: outer membrane assembly lipoprotein YfiO.
       0.774
priA
Replication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
 
    0.656
Your Current Organism:
Alistipes finegoldii
NCBI taxonomy Id: 679935
Other names: A. finegoldii DSM 17242, Alistipes finegoldii AHN 2437, Alistipes finegoldii CIP 107999, Alistipes finegoldii DSM 17242, Alistipes finegoldii str. DSM 17242, Alistipes finegoldii strain DSM 17242
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