Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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AEW04569.1Copper ion binding protein; PFAM: Heavy-metal-associated domain; TIGRFAM: copper ion binding protein; COGs: COG2608 Copper chaperone; InterPro IPR006122:IPR006121; KEGG: aac:Aaci_1114 heavy metal transport/detoxification protein; PFAM: Heavy metal transport/detoxification protein; SPTR: Heavy metal transport/detoxification protein; TIGRFAM: Copper ion-binding. (68 aa)    
Predicted Functional Partners:
AEW04478.1
PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG2217 Cation transport ATPase; InterProIPR006403:IPR006416:IPR001757:IPR006121:IPR 008250:IPR005834; KEGG: din:Selin_2151 heavy metal translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated region; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase; PRIAM: Copper-exporting ATPase; SPTR: Heavy metal translocating P-type ATPase; TIGRFAM: [...]
 
 
 0.906
AEW05588.1
PFAM: Penicillinase repressor; InterPro IPR005650; KEGG: bce:BC1719 MecI family transcriptional regulator; PFAM: Penicillinase repressor; SPTR: Transcriptional regulator, MecI.
  
  
 0.879
AEW04805.1
PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG2217 Cation transport ATPase; InterProIPR006121:IPR008250:IPR005834:IPR006403:IPR 006416:IPR001757; KEGG: sth:STH2616 putative copper-transporting ATPase; PFAM: ATPase, P-type, ATPase-associated region; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase; PRIAM: Copper-exporting ATPase; SPTR: Putative [...]
  
 
 0.873
AEW04568.1
NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154:IPR013149; KEGG: acp:A2cp1_3027 alcohol dehydrogenase zinc-binding domain protein; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SPTR: Alcohol dehydrogenase zinc-binding domain protein.
  
  
 0.774
AEW05015.1
KEGG: bts:Btus_3267 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
 0.741
AEW04804.1
Protein of unknown function DUF156; PFAM: Uncharacterised BCR, COG1937; COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: mmi:MMAR_4874 hypothetical protein; PFAM: Protein of unknown function DUF156; SPTR: Putative uncharacterized protein.
  
  
 0.696
AEW04566.1
PFAM: Glycosyl transferases group 1; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: bts:Btus_2608 glycosyl transferase group 1; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase group 1.
       0.668
AEW04567.1
Hypothetical protein.
       0.668
AEW04564.1
Metal dependent phosphohydrolase; PFAM: HD domain; COGs: COG1078 HD superfamily phosphohydrolase; InterPro IPR003607:IPR006674; KEGG: spv:SPH_1431 HD superfamily phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: Metal-dependent phosphohydrolase-like protein.
       0.601
AEW04565.1
Export-related chaperone CsaA; PFAM: Putative tRNA binding domain; TIGRFAM: export-related chaperone CsaA; InterPro IPR008231:IPR002547; KEGG: bha:BH1785 chaperonin involved in protein secretion; PFAM: tRNA-binding region; SPTR: Chaperonin involved in protein secretion; TIGRFAM: Secretion chaperone CsaA.
       0.601
Your Current Organism:
Sulfobacillus acidophilus
NCBI taxonomy Id: 679936
Other names: S. acidophilus DSM 10332, Sulfobacillus acidophilus DSM 10332, Sulfobacillus acidophilus NAL, Sulfobacillus acidophilus str. DSM 10332, Sulfobacillus acidophilus strain DSM 10332
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