STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEW06653.1PFAM: 2-nitropropane dioxygenase; COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR004136; KEGG: sth:STH2571 putative enoyl-(acyl-carrier-protein) reductase; PFAM: 2-nitropropane dioxygenase, NPD; SPTR: Putative enoyl-(Acyl-carrier-protein) reductase. (320 aa)    
Predicted Functional Partners:
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.881
AEW06654.1
Histidine triad (HIT) protein; PFAM: HIT domain; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: afr:AFE_3302 HIT family protein; PFAM: Histidine triad (HIT) protein; SPTR: Histidine triad (HIT) protein.
       0.799
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
    
 0.690
AEW04122.1
PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030:IPR014031; KEGG: gca:Galf_1156 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, C-terminal; Beta-ketoacyl synthase, N-terminal; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase I; SPTR: Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  
 0.658
AEW04300.1
Beta-ketoacyl-acyl-carrier-protein synthase II; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030:IPR014031; KEGG: adg:Adeg_0960 3-oxoacyl-(acyl-carrier-protein) synthase 2; PFAM: Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase II; SPTR: 3-oxoacyl-[acyl-carrier-protein] synthase 2; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  
 0.655
AEW05896.1
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
  
 0.655
AEW06649.1
acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155; KEGG: sth:STH725 acetyl-CoA acetyltransferase; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
    0.631
AEW05899.1
(Acyl-carrier-protein) S-malonyltransferase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043:IPR004410; KEGG: tmr:Tmar_0948 (acyl-carrier-protein) S-malonyltransferase; PFAM: Acyl transferase; PRIAM: [Acyl-carrier-protein] S-malonyltransferase; SPTR: (Acyl-carrier-protein) S-malonyltransferase; TIGRFAM: Malonyl CoA-acyl carrier protein transacylase.
 
  
 0.625
AEW06652.1
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
       0.602
AEW06650.1
Hypothetical protein.
       0.601
Your Current Organism:
Sulfobacillus acidophilus
NCBI taxonomy Id: 679936
Other names: S. acidophilus DSM 10332, Sulfobacillus acidophilus DSM 10332, Sulfobacillus acidophilus NAL, Sulfobacillus acidophilus str. DSM 10332, Sulfobacillus acidophilus strain DSM 10332
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