Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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AEW06654.1Histidine triad (HIT) protein; PFAM: HIT domain; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: afr:AFE_3302 HIT family protein; PFAM: Histidine triad (HIT) protein; SPTR: Histidine triad (HIT) protein. (131 aa)    
Predicted Functional Partners:
AEW06653.1
PFAM: 2-nitropropane dioxygenase; COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR004136; KEGG: sth:STH2571 putative enoyl-(acyl-carrier-protein) reductase; PFAM: 2-nitropropane dioxygenase, NPD; SPTR: Putative enoyl-(Acyl-carrier-protein) reductase.
       0.795
AEW04203.1
PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I; COGs: COG0174 Glutamine synthetase; InterPro IPR004809:IPR008147:IPR008146; KEGG: mta:Moth_1297 L-glutamine synthetase; PFAM: Glutamine synthetase, catalytic region; Glutamine synthetase, beta-Grasp; PRIAM: Glutamate--ammonia ligase; SPTR: Glutamine synthetase; TIGRFAM: Glutamine synthetase type I.
  
   0.704
AEW06056.1
PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I; COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146:IPR004809; KEGG: aac:Aaci_1628 glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic region; Glutamine synthetase, beta-Grasp; PRIAM: Glutamate--ammonia ligase; SPTR: Glutamine synthetase; TIGRFAM: Glutamine synthetase type I.
  
   0.704
AEW06220.1
PFAM: Glutamine synthetase, catalytic domain; TIGRFAM: glutamine synthetase, type III; COGs: COG0174 Glutamine synthetase; InterPro IPR008146:IPR017536; KEGG: tgr:Tgr7_1698 glutamine synthetase, type III; PFAM: Glutamine synthetase, catalytic region; PRIAM: Glutamate--ammonia ligase; SPTR: Glutamine synthetase, type III; TIGRFAM: Glutamine synthetase, type III.
  
   0.704
AEW06317.1
PFAM: Phosphoribulokinase / Uridine kinase family; COGs: COG0572 Uridine kinase; InterPro IPR006083; KEGG: bts:Btus_2868 phosphoribulokinase/uridine kinase; PFAM: Phosphoribulokinase/uridine kinase; PRIAM: Phosphoribulokinase; SPTR: Phosphoribulokinase.
   
 0.702
AEW06652.1
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
 0.641
AEW06649.1
acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155; KEGG: sth:STH725 acetyl-CoA acetyltransferase; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
   
   0.637
AEW06651.1
PFAM: Glycosyl transferases group 1; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: cno:NT01CX_1793 glycosyl transferase, group 1 family protein, putative; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase, group 1.
  
    0.616
lysS
PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; COGs: COG1190 Lysyl-tRNA synthetase (class II); HAMAP: Lysyl-tRNA synthetase; InterPro IPR004365:IPR004364:IPR002313; KEGG: mta:Moth_0152 lysyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: Lysine--tRNA ligase; SPTR: Lysyl-tRNA synthetase; TIGRFAM: Lysyl-tRNA synthetase, class II; Belongs to the class-II aminoacyl-tRNA synthetase family.
   
 0.612
AEW06650.1
Hypothetical protein.
       0.601
Your Current Organism:
Sulfobacillus acidophilus
NCBI taxonomy Id: 679936
Other names: S. acidophilus DSM 10332, Sulfobacillus acidophilus DSM 10332, Sulfobacillus acidophilus NAL, Sulfobacillus acidophilus str. DSM 10332, Sulfobacillus acidophilus strain DSM 10332
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