STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEW06654.1Histidine triad (HIT) protein; PFAM: HIT domain; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: afr:AFE_3302 HIT family protein; PFAM: Histidine triad (HIT) protein; SPTR: Histidine triad (HIT) protein. (131 aa)    
Predicted Functional Partners:
AEW06653.1
PFAM: 2-nitropropane dioxygenase; COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR004136; KEGG: sth:STH2571 putative enoyl-(acyl-carrier-protein) reductase; PFAM: 2-nitropropane dioxygenase, NPD; SPTR: Putative enoyl-(Acyl-carrier-protein) reductase.
       0.799
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.723
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
  0.712
AEW03616.1
PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit; COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR006935:IPR001650:IPR014001; KEGG: gya:GYMC52_2069 type III restriction protein res subunit; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: Type III restriction protein res subunit.
  
 
  0.711
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.698
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.691
AEW06652.1
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
 
 0.686
AEW05350.1
PFAM: Helicase conserved C-terminal domain; DbpA RNA binding domain; DEAD/DEAH box helicase; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR011545:IPR005580; KEGG: sth:STH1647 ATP-dependent RNA helicase; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; DbpA, RNA-binding; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: ATP-dependent RNA helicase; Belongs to the DEAD box helicase family.
  
 
 0.679
AEW05439.1
Exonuclease RNase T and DNA polymerase III; PFAM: Exonuclease; DEAD/DEAH box helicase; COGs: COG1199 Rad3-related DNA helicase; InterProIPR006055:IPR014001:IPR006555:IPR013520:IPR 011545; KEGG: sth:STH1713 ATP-dependent DNA helicase; PFAM: Exonuclease, RNase T/DNA polymerase III; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; SMART: Helicase, ATP-dependent, c2 type; Exonuclease; DEAD-like helicase, N-terminal; SPTR: ATP-dependent DNA helicase.
    
  0.649
AEW06649.1
acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155; KEGG: sth:STH725 acetyl-CoA acetyltransferase; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
   
   0.628
Your Current Organism:
Sulfobacillus acidophilus
NCBI taxonomy Id: 679936
Other names: S. acidophilus DSM 10332, Sulfobacillus acidophilus DSM 10332, Sulfobacillus acidophilus NAL, Sulfobacillus acidophilus str. DSM 10332, Sulfobacillus acidophilus strain DSM 10332
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