STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEW06960.1UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. (86 aa)    
Predicted Functional Partners:
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
  
  
 0.979
AEW06959.1
PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR020001:IPR001708; KEGG: tmr:Tmar_2371 membrane protein insertase, YidC/Oxa1 family; PFAM: Membrane insertion protein, OxaA/YidC; SPTR: Stage III sporulation protein J family protein; TIGRFAM: Membrane insertion protein, OxaA/YidC, core.
  
  
 0.969
rpmH
PFAM: Ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type; HAMAP: 50S ribosomal protein L34; InterPro IPR000271; KEGG: sus:Acid_1093 50S ribosomal protein L34P; PFAM: Ribosomal protein L34; SPTR: 50S ribosomal protein L34; TIGRFAM: Ribosomal protein L34; manually curated; IMG reference gene:2506612204_SP; Belongs to the bacterial ribosomal protein bL34 family.
  
  
 0.878
AEW05915.1
Methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR016065:IPR004398; KEGG: mta:Moth_0936 methyltransferase small; PFAM: Protein of unknown function methylase putative; SPTR: Methyltransferase small; TIGRFAM: Conserved hypothetical protein CHP00095.
  
    0.829
secE
Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
   
    0.811
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
  
    0.810
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
  
    0.806
rplB
Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
    0.719
rsmG
16S rRNA m(7)G-527 methyltransferase; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
    0.697
rplD
Ribosomal protein L4/L1e; Forms part of the polypeptide exit tunnel.
   
    0.674
Your Current Organism:
Sulfobacillus acidophilus
NCBI taxonomy Id: 679936
Other names: S. acidophilus DSM 10332, Sulfobacillus acidophilus DSM 10332, Sulfobacillus acidophilus NAL, Sulfobacillus acidophilus str. DSM 10332, Sulfobacillus acidophilus strain DSM 10332
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.