| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bcop_0002 | Bcop_0145 | Bcop_0002 | Bcop_0145 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: bfs:BF3733 nucleoside diphosphate kinase; PFAM: Nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: Nucleoside diphosphate kinase; SPTR: Nucleoside diphosphate kinase; IMG reference gene:2504105801; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family. | 0.931 |
| Bcop_0002 | Bcop_0695 | Bcop_0002 | Bcop_0695 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.858 |
| Bcop_0002 | Bcop_0907 | Bcop_0002 | Bcop_0907 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | UPF0301 protein yqgE; COGs: COG1678 Putative transcriptional regulator protein; HAMAP: Protein of unknown function DUF179; InterPro IPR003774; KEGG: bfs:BF2109 putative transcriptional regulator; PFAM: Protein of unknown function DUF179; SPTR: Putative transcriptional regulator; IMG reference gene:2504106602; PFAM: Uncharacterized ACR, COG1678; Belongs to the UPF0301 (AlgH) family. | 0.918 |
| Bcop_0002 | Bcop_1178 | Bcop_0002 | Bcop_1178 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.858 |
| Bcop_0002 | Bcop_1354 | Bcop_0002 | Bcop_1354 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.868 |
| Bcop_0002 | Bcop_1355 | Bcop_0002 | Bcop_1355 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Ribonucleotide reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.994 |
| Bcop_0002 | adk | Bcop_0002 | Bcop_0782 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.873 |
| Bcop_0002 | cmk | Bcop_0002 | Bcop_0077 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | COGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR003136:IPR011994; KEGG: bth:BT_2060 cytidylate kinase; PFAM: Cytidylate kinase domain; PRIAM: Cytidylate kinase; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase; IMG reference gene:2504105733; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase. | 0.875 |
| Bcop_0002 | gmk | Bcop_0002 | Bcop_0052 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.858 |
| Bcop_0002 | polA | Bcop_0002 | Bcop_0354 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.806 |
| Bcop_0145 | Bcop_0002 | Bcop_0145 | Bcop_0002 | COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: bfs:BF3733 nucleoside diphosphate kinase; PFAM: Nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: Nucleoside diphosphate kinase; SPTR: Nucleoside diphosphate kinase; IMG reference gene:2504105801; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family. | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.931 |
| Bcop_0145 | Bcop_0695 | Bcop_0145 | Bcop_0695 | COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: bfs:BF3733 nucleoside diphosphate kinase; PFAM: Nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: Nucleoside diphosphate kinase; SPTR: Nucleoside diphosphate kinase; IMG reference gene:2504105801; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.928 |
| Bcop_0145 | Bcop_1178 | Bcop_0145 | Bcop_1178 | COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: bfs:BF3733 nucleoside diphosphate kinase; PFAM: Nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: Nucleoside diphosphate kinase; SPTR: Nucleoside diphosphate kinase; IMG reference gene:2504105801; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family. | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.928 |
| Bcop_0145 | Bcop_1354 | Bcop_0145 | Bcop_1354 | COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: bfs:BF3733 nucleoside diphosphate kinase; PFAM: Nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: Nucleoside diphosphate kinase; SPTR: Nucleoside diphosphate kinase; IMG reference gene:2504105801; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.948 |
| Bcop_0145 | Bcop_1355 | Bcop_0145 | Bcop_1355 | COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: bfs:BF3733 nucleoside diphosphate kinase; PFAM: Nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: Nucleoside diphosphate kinase; SPTR: Nucleoside diphosphate kinase; IMG reference gene:2504105801; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family. | Ribonucleotide reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.932 |
| Bcop_0145 | adk | Bcop_0145 | Bcop_0782 | COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: bfs:BF3733 nucleoside diphosphate kinase; PFAM: Nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: Nucleoside diphosphate kinase; SPTR: Nucleoside diphosphate kinase; IMG reference gene:2504105801; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.925 |
| Bcop_0145 | cmk | Bcop_0145 | Bcop_0077 | COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: bfs:BF3733 nucleoside diphosphate kinase; PFAM: Nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: Nucleoside diphosphate kinase; SPTR: Nucleoside diphosphate kinase; IMG reference gene:2504105801; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family. | COGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR003136:IPR011994; KEGG: bth:BT_2060 cytidylate kinase; PFAM: Cytidylate kinase domain; PRIAM: Cytidylate kinase; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase; IMG reference gene:2504105733; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase. | 0.943 |
| Bcop_0145 | gmk | Bcop_0145 | Bcop_0052 | COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: bfs:BF3733 nucleoside diphosphate kinase; PFAM: Nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: Nucleoside diphosphate kinase; SPTR: Nucleoside diphosphate kinase; IMG reference gene:2504105801; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.941 |
| Bcop_0695 | Bcop_0002 | Bcop_0695 | Bcop_0002 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.858 |
| Bcop_0695 | Bcop_0145 | Bcop_0695 | Bcop_0145 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: bfs:BF3733 nucleoside diphosphate kinase; PFAM: Nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: Nucleoside diphosphate kinase; SPTR: Nucleoside diphosphate kinase; IMG reference gene:2504105801; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family. | 0.928 |