Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Bcop_0002Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (855 aa)    
Predicted Functional Partners:
Bcop_1355
Ribonucleotide reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
  
 0.994
Bcop_0145
COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: bfs:BF3733 nucleoside diphosphate kinase; PFAM: Nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: Nucleoside diphosphate kinase; SPTR: Nucleoside diphosphate kinase; IMG reference gene:2504105801; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family.
     
 0.931
Bcop_0907
UPF0301 protein yqgE; COGs: COG1678 Putative transcriptional regulator protein; HAMAP: Protein of unknown function DUF179; InterPro IPR003774; KEGG: bfs:BF2109 putative transcriptional regulator; PFAM: Protein of unknown function DUF179; SPTR: Putative transcriptional regulator; IMG reference gene:2504106602; PFAM: Uncharacterized ACR, COG1678; Belongs to the UPF0301 (AlgH) family.
   
 0.918
cmk
COGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR003136:IPR011994; KEGG: bth:BT_2060 cytidylate kinase; PFAM: Cytidylate kinase domain; PRIAM: Cytidylate kinase; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase; IMG reference gene:2504105733; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
   
 
 0.875
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
 0.873
Bcop_1354
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.868
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
 0.858
Bcop_0695
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
   
 
  0.858
Bcop_1178
GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
   
 
  0.858
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.806
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
Server load: low (16%) [HD]