| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bcop_0010 | Bcop_0011 | Bcop_0010 | Bcop_0011 | KEGG: fba:FIC_02486 aminodeoxychorismate lyase; SPTR: IlvE protein; IMG reference gene:2504105665; PFAM: Aminotransferase class IV. | Chorismate binding domain-containing protein; COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR015890; KEGG: nis:NIS_0375 para-aminobenzoate synthase component I; PFAM: Chorismate binding, C-terminal; SPTR: Aminodeoxychorismate synthase subunit I; IMG reference gene:2504105666; PFAM: chorismate binding enzyme. | 0.997 |
| Bcop_0010 | Bcop_0135 | Bcop_0010 | Bcop_0135 | KEGG: fba:FIC_02486 aminodeoxychorismate lyase; SPTR: IlvE protein; IMG reference gene:2504105665; PFAM: Aminotransferase class IV. | COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR020822:IPR002701; KEGG: bfs:BF3717 putative chorismate mutase; PFAM: DAHP synthetase I/KDSA; Chorismate mutase, type II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SMART: Chorismate mutase; SPTR: Putative uncharacterized protein; IMG reference gene:2504105791; PFAM: Chorismate mutase type II; DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase. | 0.748 |
| Bcop_0010 | Bcop_0557 | Bcop_0010 | Bcop_0557 | KEGG: fba:FIC_02486 aminodeoxychorismate lyase; SPTR: IlvE protein; IMG reference gene:2504105665; PFAM: Aminotransferase class IV. | COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489:IPR006390; KEGG: bvu:BVU_0517 dihydropteroate synthase; PFAM: Pterin-binding; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504106231; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | 0.950 |
| Bcop_0010 | Bcop_0638 | Bcop_0010 | Bcop_0638 | KEGG: fba:FIC_02486 aminodeoxychorismate lyase; SPTR: IlvE protein; IMG reference gene:2504105665; PFAM: Aminotransferase class IV. | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: bfs:BF0558 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Aspartokinase/homoserine dehydrogenase, threonine-sensitive; TIGRFAM: Aspartate kinase domain; IMG reference gene:2504106317; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; Amino acid ki [...] | 0.826 |
| Bcop_0010 | Bcop_1057 | Bcop_0010 | Bcop_1057 | KEGG: fba:FIC_02486 aminodeoxychorismate lyase; SPTR: IlvE protein; IMG reference gene:2504105665; PFAM: Aminotransferase class IV. | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR002872:IPR015590; KEGG: bvu:BVU_3604 putative proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydraogenase; PFAM: Aldehyde dehydrogenase domain; Proline dehydrogenase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106759; PFAM: Proline dehydrogenase; Aldehyde dehydrogenase family. | 0.787 |
| Bcop_0010 | Bcop_1655 | Bcop_0010 | Bcop_1655 | KEGG: fba:FIC_02486 aminodeoxychorismate lyase; SPTR: IlvE protein; IMG reference gene:2504105665; PFAM: Aminotransferase class IV. | (R)-citramalate synthase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR013709; KEGG: pdi:BDI_2061 2-isopropylmalate synthase LeuA; PFAM: Pyruvate carboxyltransferase; 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; PRIAM: (R)-citramalate synthase; SMART: 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; SPTR: 2-isopropylmalate synthase LeuA; IMG reference gene:2504107371; PFAM: LeuA allosteric (dimerisation) domain; HMGL-like; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.716 |
| Bcop_0010 | Bcop_2300 | Bcop_0010 | Bcop_2300 | KEGG: fba:FIC_02486 aminodeoxychorismate lyase; SPTR: IlvE protein; IMG reference gene:2504105665; PFAM: Aminotransferase class IV. | COGs: COG0527 Aspartokinase; InterProIPR001341:IPR001048:IPR002912:IPR005106:IPR 001342; KEGG: fjo:Fjoh_2575 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase domain; IMG reference gene:2504108025; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; Amino acid kinase family; ACT domain; TIGRFAM: aspart [...] | 0.826 |
| Bcop_0010 | Bcop_2386 | Bcop_0010 | Bcop_2386 | KEGG: fba:FIC_02486 aminodeoxychorismate lyase; SPTR: IlvE protein; IMG reference gene:2504105665; PFAM: Aminotransferase class IV. | COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: bth:BT_1747 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain; SPTR: Pyru [...] | 0.933 |
| Bcop_0010 | hisI | Bcop_0010 | Bcop_0958 | KEGG: fba:FIC_02486 aminodeoxychorismate lyase; SPTR: IlvE protein; IMG reference gene:2504105665; PFAM: Aminotransferase class IV. | Phosphoribosyl-ATP pyrophosphatase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit; In the C-terminal section; belongs to the PRA-PH family. | 0.791 |
| Bcop_0010 | ilvD | Bcop_0010 | Bcop_1653 | KEGG: fba:FIC_02486 aminodeoxychorismate lyase; SPTR: IlvE protein; IMG reference gene:2504105665; PFAM: Aminotransferase class IV. | COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; HAMAP: Dihydroxy-acid dehydratase; InterPro IPR004404:IPR000581; KEGG: pdi:BDI_2073 dihydroxy-acid dehydratase; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Dihydroxy-acid dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; IMG reference gene:2504107369; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.827 |
| Bcop_0011 | Bcop_0010 | Bcop_0011 | Bcop_0010 | Chorismate binding domain-containing protein; COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR015890; KEGG: nis:NIS_0375 para-aminobenzoate synthase component I; PFAM: Chorismate binding, C-terminal; SPTR: Aminodeoxychorismate synthase subunit I; IMG reference gene:2504105666; PFAM: chorismate binding enzyme. | KEGG: fba:FIC_02486 aminodeoxychorismate lyase; SPTR: IlvE protein; IMG reference gene:2504105665; PFAM: Aminotransferase class IV. | 0.997 |
| Bcop_0011 | Bcop_0135 | Bcop_0011 | Bcop_0135 | Chorismate binding domain-containing protein; COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR015890; KEGG: nis:NIS_0375 para-aminobenzoate synthase component I; PFAM: Chorismate binding, C-terminal; SPTR: Aminodeoxychorismate synthase subunit I; IMG reference gene:2504105666; PFAM: chorismate binding enzyme. | COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR020822:IPR002701; KEGG: bfs:BF3717 putative chorismate mutase; PFAM: DAHP synthetase I/KDSA; Chorismate mutase, type II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SMART: Chorismate mutase; SPTR: Putative uncharacterized protein; IMG reference gene:2504105791; PFAM: Chorismate mutase type II; DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase. | 0.931 |
| Bcop_0011 | Bcop_0557 | Bcop_0011 | Bcop_0557 | Chorismate binding domain-containing protein; COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR015890; KEGG: nis:NIS_0375 para-aminobenzoate synthase component I; PFAM: Chorismate binding, C-terminal; SPTR: Aminodeoxychorismate synthase subunit I; IMG reference gene:2504105666; PFAM: chorismate binding enzyme. | COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489:IPR006390; KEGG: bvu:BVU_0517 dihydropteroate synthase; PFAM: Pterin-binding; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504106231; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | 0.643 |
| Bcop_0011 | hisI | Bcop_0011 | Bcop_0958 | Chorismate binding domain-containing protein; COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR015890; KEGG: nis:NIS_0375 para-aminobenzoate synthase component I; PFAM: Chorismate binding, C-terminal; SPTR: Aminodeoxychorismate synthase subunit I; IMG reference gene:2504105666; PFAM: chorismate binding enzyme. | Phosphoribosyl-ATP pyrophosphatase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit; In the C-terminal section; belongs to the PRA-PH family. | 0.614 |
| Bcop_0135 | Bcop_0010 | Bcop_0135 | Bcop_0010 | COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR020822:IPR002701; KEGG: bfs:BF3717 putative chorismate mutase; PFAM: DAHP synthetase I/KDSA; Chorismate mutase, type II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SMART: Chorismate mutase; SPTR: Putative uncharacterized protein; IMG reference gene:2504105791; PFAM: Chorismate mutase type II; DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase. | KEGG: fba:FIC_02486 aminodeoxychorismate lyase; SPTR: IlvE protein; IMG reference gene:2504105665; PFAM: Aminotransferase class IV. | 0.748 |
| Bcop_0135 | Bcop_0011 | Bcop_0135 | Bcop_0011 | COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR020822:IPR002701; KEGG: bfs:BF3717 putative chorismate mutase; PFAM: DAHP synthetase I/KDSA; Chorismate mutase, type II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SMART: Chorismate mutase; SPTR: Putative uncharacterized protein; IMG reference gene:2504105791; PFAM: Chorismate mutase type II; DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase. | Chorismate binding domain-containing protein; COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR015890; KEGG: nis:NIS_0375 para-aminobenzoate synthase component I; PFAM: Chorismate binding, C-terminal; SPTR: Aminodeoxychorismate synthase subunit I; IMG reference gene:2504105666; PFAM: chorismate binding enzyme. | 0.931 |
| Bcop_0135 | Bcop_0638 | Bcop_0135 | Bcop_0638 | COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR020822:IPR002701; KEGG: bfs:BF3717 putative chorismate mutase; PFAM: DAHP synthetase I/KDSA; Chorismate mutase, type II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SMART: Chorismate mutase; SPTR: Putative uncharacterized protein; IMG reference gene:2504105791; PFAM: Chorismate mutase type II; DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase. | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: bfs:BF0558 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Aspartokinase/homoserine dehydrogenase, threonine-sensitive; TIGRFAM: Aspartate kinase domain; IMG reference gene:2504106317; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; Amino acid ki [...] | 0.732 |
| Bcop_0135 | Bcop_1057 | Bcop_0135 | Bcop_1057 | COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR020822:IPR002701; KEGG: bfs:BF3717 putative chorismate mutase; PFAM: DAHP synthetase I/KDSA; Chorismate mutase, type II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SMART: Chorismate mutase; SPTR: Putative uncharacterized protein; IMG reference gene:2504105791; PFAM: Chorismate mutase type II; DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase. | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR002872:IPR015590; KEGG: bvu:BVU_3604 putative proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydraogenase; PFAM: Aldehyde dehydrogenase domain; Proline dehydrogenase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106759; PFAM: Proline dehydrogenase; Aldehyde dehydrogenase family. | 0.758 |
| Bcop_0135 | Bcop_1655 | Bcop_0135 | Bcop_1655 | COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR020822:IPR002701; KEGG: bfs:BF3717 putative chorismate mutase; PFAM: DAHP synthetase I/KDSA; Chorismate mutase, type II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SMART: Chorismate mutase; SPTR: Putative uncharacterized protein; IMG reference gene:2504105791; PFAM: Chorismate mutase type II; DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase. | (R)-citramalate synthase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR013709; KEGG: pdi:BDI_2061 2-isopropylmalate synthase LeuA; PFAM: Pyruvate carboxyltransferase; 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; PRIAM: (R)-citramalate synthase; SMART: 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; SPTR: 2-isopropylmalate synthase LeuA; IMG reference gene:2504107371; PFAM: LeuA allosteric (dimerisation) domain; HMGL-like; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.401 |
| Bcop_0135 | Bcop_2300 | Bcop_0135 | Bcop_2300 | COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR020822:IPR002701; KEGG: bfs:BF3717 putative chorismate mutase; PFAM: DAHP synthetase I/KDSA; Chorismate mutase, type II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SMART: Chorismate mutase; SPTR: Putative uncharacterized protein; IMG reference gene:2504105791; PFAM: Chorismate mutase type II; DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase. | COGs: COG0527 Aspartokinase; InterProIPR001341:IPR001048:IPR002912:IPR005106:IPR 001342; KEGG: fjo:Fjoh_2575 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase domain; IMG reference gene:2504108025; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; Amino acid kinase family; ACT domain; TIGRFAM: aspart [...] | 0.732 |