STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bcop_0104COGs: COG1560 Lauroyl/myristoyl acyltransferase; InterPro IPR004960; KEGG: bfs:BF3626 putative LipD A biosynthesis related exported protein; PFAM: Bacterial lipid A biosynthesis acyltransferase; SPTR: Putative acetyltransferase; IMG reference gene:2504105760; PFAM: Bacterial lipid A biosynthesis acyltransferase. (297 aa)    
Predicted Functional Partners:
Bcop_0503
Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
  
 0.963
Bcop_0103
COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: bth:BT_2151 glycosyltransferase; PFAM: Glycosyl transferase, family 2; SPTR: Putative uncharacterized protein; IMG reference gene:2504105759; PFAM: Glycosyl transferase family 2.
 
  
 0.881
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
       0.844
Bcop_0105
MiaB-like tRNA modifying enzyme; COGs: COG0621 2-methylthioadenine synthetase; InterProIPR005839:IPR006467:IPR013848:IPR007197:IPR 006638; KEGG: bth:BT_2153 putative Fe-S oxidoreductase; PFAM: Methylthiotransferase, N-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; TIGRFAM: MiaB-like tRNA modifying enzyme; Methylthiotransferase; IMG reference gene:2504105761; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme; radical SAM methylthiotransferase, MiaB/RimO family.
       0.844
Bcop_0309
COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201; KEGG: bth:BT_3362 heptosyltransferase; PFAM: Glycosyl transferase, family 9; SPTR: Putative ADP-heptose--LPS heptosyltransferase; IMG reference gene:2504105970; PFAM: Glycosyltransferase family 9 (heptosyltransferase).
 
  
 0.762
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
 
 0.759
Bcop_0701
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.705
Bcop_0752
acyl-(acyl-carrier-protein)--UDP-N-acetylglucosa mineO-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.704
lpxD
UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
   
 0.701
fabZ
(3R)-hydroxymyristoyl-(acyl-carrier- protein)dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
 
   
 0.661
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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