STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (698 aa)    
Predicted Functional Partners:
Bcop_0149
TonB family protein; InterPro IPR006260; KEGG: bfs:BF3737 putative TonB exported protein; SPTR: Putative TonB exported protein; TIGRFAM: TonB, C-terminal; IMG reference gene:2504105805; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain.
  
    0.845
ispD
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
       0.844
Bcop_0148
DJ-1 family protein; COGs: COG0693 Putative intracellular protease/amidase; InterPro IPR006287:IPR002818; KEGG: bfs:BF3736 putative thiamine biosynthesis-like protein; PFAM: ThiJ/PfpI; SPTR: ThiJ/PfpI family protein; TIGRFAM: DJ-1; IMG reference gene:2504105804; PFAM: DJ-1/PfpI family; TIGRFAM: DJ-1 family protein.
       0.844
Bcop_0150
COGs: COG0848 Biopolymer transport protein; InterPro IPR003400; KEGG: bfs:BF3738 putative tansport-like protein; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: Putative biopolymer transport protein ExbD; IMG reference gene:2504105806; PFAM: Biopolymer transport protein ExbD/TolR.
       0.844
pdxJ
Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
     
 0.722
Bcop_0151
MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: bfs:BF3739 putative transport related membrane protein; PFAM: MotA/TolQ/ExbB proton channel; SPTR: Putative uncharacterized protein; IMG reference gene:2504105807; PFAM: MotA/TolQ/ExbB proton channel family.
     
 0.689
Bcop_0145
COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: bfs:BF3733 nucleoside diphosphate kinase; PFAM: Nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: Nucleoside diphosphate kinase; SPTR: Nucleoside diphosphate kinase; IMG reference gene:2504105801; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family.
  
    0.670
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
   
 0.616
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.604
miaA
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
  
     0.593
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
Server load: medium (64%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.