STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Bcop_0171Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: bvu:BVU_1638 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; PFAM: Fumarylacetoacetase, C-terminal-like; SPTR: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; IMG reference gene:2504105827; PFAM: Fumarylacetoacetate (FAA) hydrolase family. (200 aa)    
Predicted Functional Partners:
ispF
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
       0.844
rex
Redox-sensing transcriptional repressor rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
       0.844
Bcop_0448
COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953:IPR004112:IPR011280; KEGG: bfs:BF4340 succinate dehydrogenase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; PRIAM: Succinate dehydrogenase; SPTR: Fumarate reductase flavoprotein subunit; TIGRFAM: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, low-GC Gram-positive bacteria; IMG reference gene:2504106112; PFAM: domain; FAD binding domain; TIGRFAM: succina [...]
  
 
 0.768
Bcop_0173
COGs: COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related protein; InterPro IPR001950; KEGG: bfr:BF4009 putative translation initiation factor SUI1; PFAM: Translation initiation factor SUI1; SPTR: Putative uncharacterized protein; IMG reference gene:2504105829; PFAM: Translation initiation factor SUI1; TIGRFAM: translation initation factor SUI1, putative, prokaryotic.
 
     0.747
Bcop_0447
COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR001041:IPR001450:IPR004489; KEGG: bfs:BF4341 succinate dehydrogenase/fumarate reductase iron-sulfur subunit; PFAM: 4Fe-4S binding domain; Ferredoxin; SPTR: Fumarate reductase iron-sulfur cluster protein subunit; TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein; IMG reference gene:2504106111; PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein.
  
 
  0.745
Bcop_0535
D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: bfs:BF0370 putative FAD-binding oxidoreductase; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Putative uncharacterized protein; IMG reference gene:2504106209; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain.
 
 
 0.741
Bcop_0449
Succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; InterPro IPR011138; KEGG: bfs:BF4339 fumarate reductase transmembrane cytochrome b subunit; SPTR: Fumarate reductase cytochrome b subunit; TIGRFAM: Succinate dehydrogenase, cytochrome b558 subunit; IMG reference gene:2504106113; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family.
    
  0.737
Bcop_1057
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR002872:IPR015590; KEGG: bvu:BVU_3604 putative proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydraogenase; PFAM: Aldehyde dehydrogenase domain; Proline dehydrogenase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106759; PFAM: Proline dehydrogenase; Aldehyde dehydrogenase family.
 
 
 0.734
Bcop_0166
Exonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
   
   0.585
Bcop_1145
Glyoxylate reductase; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: bfs:BF1944 glycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; PRIAM: Glyoxylate reductase; SPTR: Glycerate dehydrogenase; IMG reference gene:2504106848; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
 
  0.549
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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