STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bcop_0187COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: fjo:Fjoh_2879 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504105844; PFAM: HAMP domain; Histi [...] (464 aa)    
Predicted Functional Partners:
Bcop_0188
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: fjo:Fjoh_2880 two component transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Two component transcriptional regulator, winged helix family protein; IMG reference gen [...]
  0.977
Bcop_1805
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: fjo:Fjoh_4291 two component transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Two component transcriptional regulator, winged helix family; manually curated; IMG ref [...]
 
  0.896
Bcop_0870
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: bfr:BF0209 two-component system response regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504106560; PFAM: Response regulator [...]
 
  0.894
Bcop_1492
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: cpi:Cpin_4882 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Two-component system response regulator; IMG reference gene:250410 [...]
 
  0.873
Bcop_0897
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: bfs:BF1590 putative two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504106592; PFAM: Response regulato [...]
  
   0.843
Bcop_2322
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: bth:BT_1482 two-component system response regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504108053; PFAM: Response regulator [...]
  
   0.843
Bcop_0113
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: bfs:BF3634 two-component system, transcriptional regulatory protein; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Transcriptional regulator; IMG reference gene:2504105769; PFAM: Response [...]
  
  0.837
Bcop_2376
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR011110:IPR011123:IPR003594:IPR001789:IPR 000005:IPR018060; KEGG: bfs:BF3155 putative two-component system sensor kinase/response regulator fusion protein; PFAM: Signal transduction response regulator, receiver domain; Two component regulator three Y; Two component regulator propeller; ATPase-like, ATP-binding domain; HTH transcriptional regulator, AraC; SMART: Helix-turn-helix, AraC type, DNA binding domain; Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; SPTR: Two [...]
  
 0.795
Bcop_1264
Two component transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterProIPR011110:IPR011123:IPR003661:IPR001789:IPR 000005:IPR018060; KEGG: bth:BT_2628 two-component system sensor histidine kinase/response regulator, hybrid ('one-component system'); PFAM: HTH transcriptional regulator, AraC; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Two component regulator three Y; Two component regulator propeller; Signal transduction response regulator, receiver domain; SMART: Helix-turn-helix, AraC type [...]
  
 0.784
Bcop_1683
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR011123:IPR003661:IPR003594:IPR001789:IPR 000005:IPR018060; KEGG: bth:BT_3678 two-component system sensor histidine kinase/response regulator, hybrid ('one-component system'); PFAM: ATPase-like, ATP-binding domain; Two component regulator three Y; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; HTH transcriptional regulator, AraC; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgr [...]
  
0.784
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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