| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bcop_0008 | Bcop_0331 | Bcop_0008 | Bcop_0331 | Malic protein NAD-binding; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: bth:BT_1969 malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SMART: Malic enzyme, NAD-binding; SPTR: NADP-dependent malic enzyme; IMG reference gene:2504105663; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain. | Protein of unknown function DUF1730; COGs: COG1600 Uncharacterized Fe-S protein; InterPro IPR013542:IPR001450; KEGG: bfs:BF0085 putative iron-sulfur cluster-binding protein; PFAM: Domain of unknown function DUF1730; 4Fe-4S binding domain; SPTR: Putative iron-sulfur cluster-binding protein; IMG reference gene:2504105992; PFAM: Domain of unknown function (DUF1730); TIGRFAM: iron-sulfur cluster binding protein, putative. | 0.824 |
| Bcop_0008 | Bcop_0433 | Bcop_0008 | Bcop_0433 | Malic protein NAD-binding; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: bth:BT_1969 malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SMART: Malic enzyme, NAD-binding; SPTR: NADP-dependent malic enzyme; IMG reference gene:2504105663; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain. | 2-oxoacid:acceptor oxidoreductase, alpha subunit; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752:IPR002880:IPR022367; KEGG: bth:BT_2836 2-oxoglutarate synthase subunit KorA; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; PRIAM: 2-oxoglutarate synthase; SPTR: Pyruvate synthase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; IMG reference gene:2504106097; PFAM: domain; Transketolase, C-terminal domain; Pyruvate ferred [...] | 0.943 |
| Bcop_0008 | Bcop_0680 | Bcop_0008 | Bcop_0680 | Malic protein NAD-binding; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: bth:BT_1969 malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SMART: Malic enzyme, NAD-binding; SPTR: NADP-dependent malic enzyme; IMG reference gene:2504105663; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.522 |
| Bcop_0008 | Bcop_2180 | Bcop_0008 | Bcop_2180 | Malic protein NAD-binding; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: bth:BT_1969 malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SMART: Malic enzyme, NAD-binding; SPTR: NADP-dependent malic enzyme; IMG reference gene:2504105663; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain. | COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475:IPR005476; KEGG: bfs:BF1660 putative transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: Formaldehyde transketolase; SMART: Transketolase-like, pyrimidine-binding domain; SPTR: Transketolase; IMG reference gene:2504107901; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; Belongs to the transketolase family. | 0.851 |
| Bcop_0008 | Bcop_2386 | Bcop_0008 | Bcop_2386 | Malic protein NAD-binding; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: bth:BT_1969 malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SMART: Malic enzyme, NAD-binding; SPTR: NADP-dependent malic enzyme; IMG reference gene:2504105663; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain. | COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: bth:BT_1747 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain; SPTR: Pyru [...] | 0.995 |
| Bcop_0328 | Bcop_0329 | Bcop_0328 | Bcop_0329 | ABC transporter related protein; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: bth:BT_3248 putative metal ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504105989; PFAM: ABC transporter. | KEGG: bth:BT_3247 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504105990; PFAM: Protein of unknown function (DUF2723). | 0.629 |
| Bcop_0328 | Bcop_0330 | Bcop_0328 | Bcop_0330 | ABC transporter related protein; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: bth:BT_3248 putative metal ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504105989; PFAM: ABC transporter. | COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: bfs:BF0086 putative polysaccharide deacetylase; PFAM: Polysaccharide deacetylase; SPTR: Polysaccharide deacetylase; IMG reference gene:2504105991; PFAM: Polysaccharide deacetylase. | 0.553 |
| Bcop_0328 | Bcop_0331 | Bcop_0328 | Bcop_0331 | ABC transporter related protein; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: bth:BT_3248 putative metal ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504105989; PFAM: ABC transporter. | Protein of unknown function DUF1730; COGs: COG1600 Uncharacterized Fe-S protein; InterPro IPR013542:IPR001450; KEGG: bfs:BF0085 putative iron-sulfur cluster-binding protein; PFAM: Domain of unknown function DUF1730; 4Fe-4S binding domain; SPTR: Putative iron-sulfur cluster-binding protein; IMG reference gene:2504105992; PFAM: Domain of unknown function (DUF1730); TIGRFAM: iron-sulfur cluster binding protein, putative. | 0.502 |
| Bcop_0329 | Bcop_0328 | Bcop_0329 | Bcop_0328 | KEGG: bth:BT_3247 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504105990; PFAM: Protein of unknown function (DUF2723). | ABC transporter related protein; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: bth:BT_3248 putative metal ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504105989; PFAM: ABC transporter. | 0.629 |
| Bcop_0329 | Bcop_0330 | Bcop_0329 | Bcop_0330 | KEGG: bth:BT_3247 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504105990; PFAM: Protein of unknown function (DUF2723). | COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: bfs:BF0086 putative polysaccharide deacetylase; PFAM: Polysaccharide deacetylase; SPTR: Polysaccharide deacetylase; IMG reference gene:2504105991; PFAM: Polysaccharide deacetylase. | 0.687 |
| Bcop_0329 | Bcop_0331 | Bcop_0329 | Bcop_0331 | KEGG: bth:BT_3247 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504105990; PFAM: Protein of unknown function (DUF2723). | Protein of unknown function DUF1730; COGs: COG1600 Uncharacterized Fe-S protein; InterPro IPR013542:IPR001450; KEGG: bfs:BF0085 putative iron-sulfur cluster-binding protein; PFAM: Domain of unknown function DUF1730; 4Fe-4S binding domain; SPTR: Putative iron-sulfur cluster-binding protein; IMG reference gene:2504105992; PFAM: Domain of unknown function (DUF1730); TIGRFAM: iron-sulfur cluster binding protein, putative. | 0.687 |
| Bcop_0330 | Bcop_0328 | Bcop_0330 | Bcop_0328 | COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: bfs:BF0086 putative polysaccharide deacetylase; PFAM: Polysaccharide deacetylase; SPTR: Polysaccharide deacetylase; IMG reference gene:2504105991; PFAM: Polysaccharide deacetylase. | ABC transporter related protein; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: bth:BT_3248 putative metal ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504105989; PFAM: ABC transporter. | 0.553 |
| Bcop_0330 | Bcop_0329 | Bcop_0330 | Bcop_0329 | COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: bfs:BF0086 putative polysaccharide deacetylase; PFAM: Polysaccharide deacetylase; SPTR: Polysaccharide deacetylase; IMG reference gene:2504105991; PFAM: Polysaccharide deacetylase. | KEGG: bth:BT_3247 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504105990; PFAM: Protein of unknown function (DUF2723). | 0.687 |
| Bcop_0330 | Bcop_0331 | Bcop_0330 | Bcop_0331 | COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: bfs:BF0086 putative polysaccharide deacetylase; PFAM: Polysaccharide deacetylase; SPTR: Polysaccharide deacetylase; IMG reference gene:2504105991; PFAM: Polysaccharide deacetylase. | Protein of unknown function DUF1730; COGs: COG1600 Uncharacterized Fe-S protein; InterPro IPR013542:IPR001450; KEGG: bfs:BF0085 putative iron-sulfur cluster-binding protein; PFAM: Domain of unknown function DUF1730; 4Fe-4S binding domain; SPTR: Putative iron-sulfur cluster-binding protein; IMG reference gene:2504105992; PFAM: Domain of unknown function (DUF1730); TIGRFAM: iron-sulfur cluster binding protein, putative. | 0.821 |
| Bcop_0331 | Bcop_0008 | Bcop_0331 | Bcop_0008 | Protein of unknown function DUF1730; COGs: COG1600 Uncharacterized Fe-S protein; InterPro IPR013542:IPR001450; KEGG: bfs:BF0085 putative iron-sulfur cluster-binding protein; PFAM: Domain of unknown function DUF1730; 4Fe-4S binding domain; SPTR: Putative iron-sulfur cluster-binding protein; IMG reference gene:2504105992; PFAM: Domain of unknown function (DUF1730); TIGRFAM: iron-sulfur cluster binding protein, putative. | Malic protein NAD-binding; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: bth:BT_1969 malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SMART: Malic enzyme, NAD-binding; SPTR: NADP-dependent malic enzyme; IMG reference gene:2504105663; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain. | 0.824 |
| Bcop_0331 | Bcop_0328 | Bcop_0331 | Bcop_0328 | Protein of unknown function DUF1730; COGs: COG1600 Uncharacterized Fe-S protein; InterPro IPR013542:IPR001450; KEGG: bfs:BF0085 putative iron-sulfur cluster-binding protein; PFAM: Domain of unknown function DUF1730; 4Fe-4S binding domain; SPTR: Putative iron-sulfur cluster-binding protein; IMG reference gene:2504105992; PFAM: Domain of unknown function (DUF1730); TIGRFAM: iron-sulfur cluster binding protein, putative. | ABC transporter related protein; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: bth:BT_3248 putative metal ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504105989; PFAM: ABC transporter. | 0.502 |
| Bcop_0331 | Bcop_0329 | Bcop_0331 | Bcop_0329 | Protein of unknown function DUF1730; COGs: COG1600 Uncharacterized Fe-S protein; InterPro IPR013542:IPR001450; KEGG: bfs:BF0085 putative iron-sulfur cluster-binding protein; PFAM: Domain of unknown function DUF1730; 4Fe-4S binding domain; SPTR: Putative iron-sulfur cluster-binding protein; IMG reference gene:2504105992; PFAM: Domain of unknown function (DUF1730); TIGRFAM: iron-sulfur cluster binding protein, putative. | KEGG: bth:BT_3247 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504105990; PFAM: Protein of unknown function (DUF2723). | 0.687 |
| Bcop_0331 | Bcop_0330 | Bcop_0331 | Bcop_0330 | Protein of unknown function DUF1730; COGs: COG1600 Uncharacterized Fe-S protein; InterPro IPR013542:IPR001450; KEGG: bfs:BF0085 putative iron-sulfur cluster-binding protein; PFAM: Domain of unknown function DUF1730; 4Fe-4S binding domain; SPTR: Putative iron-sulfur cluster-binding protein; IMG reference gene:2504105992; PFAM: Domain of unknown function (DUF1730); TIGRFAM: iron-sulfur cluster binding protein, putative. | COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: bfs:BF0086 putative polysaccharide deacetylase; PFAM: Polysaccharide deacetylase; SPTR: Polysaccharide deacetylase; IMG reference gene:2504105991; PFAM: Polysaccharide deacetylase. | 0.821 |
| Bcop_0331 | Bcop_0433 | Bcop_0331 | Bcop_0433 | Protein of unknown function DUF1730; COGs: COG1600 Uncharacterized Fe-S protein; InterPro IPR013542:IPR001450; KEGG: bfs:BF0085 putative iron-sulfur cluster-binding protein; PFAM: Domain of unknown function DUF1730; 4Fe-4S binding domain; SPTR: Putative iron-sulfur cluster-binding protein; IMG reference gene:2504105992; PFAM: Domain of unknown function (DUF1730); TIGRFAM: iron-sulfur cluster binding protein, putative. | 2-oxoacid:acceptor oxidoreductase, alpha subunit; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752:IPR002880:IPR022367; KEGG: bth:BT_2836 2-oxoglutarate synthase subunit KorA; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; PRIAM: 2-oxoglutarate synthase; SPTR: Pyruvate synthase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; IMG reference gene:2504106097; PFAM: domain; Transketolase, C-terminal domain; Pyruvate ferred [...] | 0.698 |
| Bcop_0331 | Bcop_0680 | Bcop_0331 | Bcop_0680 | Protein of unknown function DUF1730; COGs: COG1600 Uncharacterized Fe-S protein; InterPro IPR013542:IPR001450; KEGG: bfs:BF0085 putative iron-sulfur cluster-binding protein; PFAM: Domain of unknown function DUF1730; 4Fe-4S binding domain; SPTR: Putative iron-sulfur cluster-binding protein; IMG reference gene:2504105992; PFAM: Domain of unknown function (DUF1730); TIGRFAM: iron-sulfur cluster binding protein, putative. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.533 |