| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bcop_0116 | miaB | Bcop_0116 | Bcop_0359 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | (Dimethylallyl)adenosine tRNA methylthiotransferase miaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.478 |
| Bcop_0116 | rlmN | Bcop_0116 | Bcop_2403 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.657 |
| Bcop_0357 | miaB | Bcop_0357 | Bcop_0359 | Succinate CoA transferase; COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR003702:IPR017821; KEGG: bfs:BF0025 putative CoA transferase; PFAM: Acetyl-CoA hydrolase/transferase; PRIAM: Acetyl-CoA hydrolase; SPTR: Putative uncharacterized protein; TIGRFAM: Succinate CoA transferase; IMG reference gene:2504106018; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain; TIGRFAM: succinate CoA transferases. | (Dimethylallyl)adenosine tRNA methylthiotransferase miaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.567 |
| Bcop_0360 | Bcop_0361 | Bcop_0360 | Bcop_0361 | Methyltransferase type 12; InterPro IPR013217; KEGG: bfr:BF0053 hypothetical protein; PFAM: Methyltransferase type 12; SPTR: Methyltransferase domain protein; IMG reference gene:2504106021; PFAM: Methyltransferase domain. | Protein of unknown function DUF214; COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: bfs:BF0066 putative cell division protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Efflux ABC transporter, permease protein; IMG reference gene:2504106022; PFAM: Predicted permease. | 0.848 |
| Bcop_0360 | Bcop_0362 | Bcop_0360 | Bcop_0362 | Methyltransferase type 12; InterPro IPR013217; KEGG: bfr:BF0053 hypothetical protein; PFAM: Methyltransferase type 12; SPTR: Methyltransferase domain protein; IMG reference gene:2504106021; PFAM: Methyltransferase domain. | KEGG: bvu:BVU_1170 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504106023; PFAM: Protein of unknown function (DUF3098). | 0.837 |
| Bcop_0360 | Bcop_0625 | Bcop_0360 | Bcop_0625 | Methyltransferase type 12; InterPro IPR013217; KEGG: bfr:BF0053 hypothetical protein; PFAM: Methyltransferase type 12; SPTR: Methyltransferase domain protein; IMG reference gene:2504106021; PFAM: Methyltransferase domain. | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | 0.657 |
| Bcop_0360 | miaB | Bcop_0360 | Bcop_0359 | Methyltransferase type 12; InterPro IPR013217; KEGG: bfr:BF0053 hypothetical protein; PFAM: Methyltransferase type 12; SPTR: Methyltransferase domain protein; IMG reference gene:2504106021; PFAM: Methyltransferase domain. | (Dimethylallyl)adenosine tRNA methylthiotransferase miaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.549 |
| Bcop_0360 | queA | Bcop_0360 | Bcop_0365 | Methyltransferase type 12; InterPro IPR013217; KEGG: bfr:BF0053 hypothetical protein; PFAM: Methyltransferase type 12; SPTR: Methyltransferase domain protein; IMG reference gene:2504106021; PFAM: Methyltransferase domain. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.697 |
| Bcop_0360 | truB | Bcop_0360 | Bcop_0364 | Methyltransferase type 12; InterPro IPR013217; KEGG: bfr:BF0053 hypothetical protein; PFAM: Methyltransferase type 12; SPTR: Methyltransferase domain protein; IMG reference gene:2504106021; PFAM: Methyltransferase domain. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.787 |
| Bcop_0360 | uppP | Bcop_0360 | Bcop_0363 | Methyltransferase type 12; InterPro IPR013217; KEGG: bfr:BF0053 hypothetical protein; PFAM: Methyltransferase type 12; SPTR: Methyltransferase domain protein; IMG reference gene:2504106021; PFAM: Methyltransferase domain. | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.788 |
| Bcop_0361 | Bcop_0360 | Bcop_0361 | Bcop_0360 | Protein of unknown function DUF214; COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: bfs:BF0066 putative cell division protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Efflux ABC transporter, permease protein; IMG reference gene:2504106022; PFAM: Predicted permease. | Methyltransferase type 12; InterPro IPR013217; KEGG: bfr:BF0053 hypothetical protein; PFAM: Methyltransferase type 12; SPTR: Methyltransferase domain protein; IMG reference gene:2504106021; PFAM: Methyltransferase domain. | 0.848 |
| Bcop_0361 | Bcop_0362 | Bcop_0361 | Bcop_0362 | Protein of unknown function DUF214; COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: bfs:BF0066 putative cell division protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Efflux ABC transporter, permease protein; IMG reference gene:2504106022; PFAM: Predicted permease. | KEGG: bvu:BVU_1170 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504106023; PFAM: Protein of unknown function (DUF3098). | 0.831 |
| Bcop_0361 | miaB | Bcop_0361 | Bcop_0359 | Protein of unknown function DUF214; COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: bfs:BF0066 putative cell division protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Efflux ABC transporter, permease protein; IMG reference gene:2504106022; PFAM: Predicted permease. | (Dimethylallyl)adenosine tRNA methylthiotransferase miaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.495 |
| Bcop_0361 | queA | Bcop_0361 | Bcop_0365 | Protein of unknown function DUF214; COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: bfs:BF0066 putative cell division protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Efflux ABC transporter, permease protein; IMG reference gene:2504106022; PFAM: Predicted permease. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.697 |
| Bcop_0361 | truB | Bcop_0361 | Bcop_0364 | Protein of unknown function DUF214; COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: bfs:BF0066 putative cell division protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Efflux ABC transporter, permease protein; IMG reference gene:2504106022; PFAM: Predicted permease. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.778 |
| Bcop_0361 | uppP | Bcop_0361 | Bcop_0363 | Protein of unknown function DUF214; COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: bfs:BF0066 putative cell division protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Efflux ABC transporter, permease protein; IMG reference gene:2504106022; PFAM: Predicted permease. | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.791 |
| Bcop_0362 | Bcop_0360 | Bcop_0362 | Bcop_0360 | KEGG: bvu:BVU_1170 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504106023; PFAM: Protein of unknown function (DUF3098). | Methyltransferase type 12; InterPro IPR013217; KEGG: bfr:BF0053 hypothetical protein; PFAM: Methyltransferase type 12; SPTR: Methyltransferase domain protein; IMG reference gene:2504106021; PFAM: Methyltransferase domain. | 0.837 |
| Bcop_0362 | Bcop_0361 | Bcop_0362 | Bcop_0361 | KEGG: bvu:BVU_1170 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504106023; PFAM: Protein of unknown function (DUF3098). | Protein of unknown function DUF214; COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: bfs:BF0066 putative cell division protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Efflux ABC transporter, permease protein; IMG reference gene:2504106022; PFAM: Predicted permease. | 0.831 |
| Bcop_0362 | miaB | Bcop_0362 | Bcop_0359 | KEGG: bvu:BVU_1170 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504106023; PFAM: Protein of unknown function (DUF3098). | (Dimethylallyl)adenosine tRNA methylthiotransferase miaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.476 |
| Bcop_0362 | queA | Bcop_0362 | Bcop_0365 | KEGG: bvu:BVU_1170 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504106023; PFAM: Protein of unknown function (DUF3098). | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.788 |