| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bcop_0361 | Bcop_0362 | Bcop_0361 | Bcop_0362 | Protein of unknown function DUF214; COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: bfs:BF0066 putative cell division protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Efflux ABC transporter, permease protein; IMG reference gene:2504106022; PFAM: Predicted permease. | KEGG: bvu:BVU_1170 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504106023; PFAM: Protein of unknown function (DUF3098). | 0.808 |
| Bcop_0361 | queA | Bcop_0361 | Bcop_0365 | Protein of unknown function DUF214; COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: bfs:BF0066 putative cell division protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Efflux ABC transporter, permease protein; IMG reference gene:2504106022; PFAM: Predicted permease. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.723 |
| Bcop_0361 | truB | Bcop_0361 | Bcop_0364 | Protein of unknown function DUF214; COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: bfs:BF0066 putative cell division protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Efflux ABC transporter, permease protein; IMG reference gene:2504106022; PFAM: Predicted permease. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.796 |
| Bcop_0361 | uppP | Bcop_0361 | Bcop_0363 | Protein of unknown function DUF214; COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: bfs:BF0066 putative cell division protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Efflux ABC transporter, permease protein; IMG reference gene:2504106022; PFAM: Predicted permease. | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.796 |
| Bcop_0362 | Bcop_0361 | Bcop_0362 | Bcop_0361 | KEGG: bvu:BVU_1170 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504106023; PFAM: Protein of unknown function (DUF3098). | Protein of unknown function DUF214; COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: bfs:BF0066 putative cell division protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Efflux ABC transporter, permease protein; IMG reference gene:2504106022; PFAM: Predicted permease. | 0.808 |
| Bcop_0362 | queA | Bcop_0362 | Bcop_0365 | KEGG: bvu:BVU_1170 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504106023; PFAM: Protein of unknown function (DUF3098). | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.761 |
| Bcop_0362 | truB | Bcop_0362 | Bcop_0364 | KEGG: bvu:BVU_1170 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504106023; PFAM: Protein of unknown function (DUF3098). | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.821 |
| Bcop_0362 | uppP | Bcop_0362 | Bcop_0363 | KEGG: bvu:BVU_1170 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504106023; PFAM: Protein of unknown function (DUF3098). | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.821 |
| Bcop_0481 | guaA | Bcop_0481 | Bcop_0946 | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR015865:IPR015864:IPR002606; KEGG: bfs:BF4147 putative riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SMART: Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; IMG reference gene:2504106148; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.404 |
| Bcop_0481 | truA | Bcop_0481 | Bcop_0773 | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR015865:IPR015864:IPR002606; KEGG: bfs:BF4147 putative riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SMART: Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; IMG reference gene:2504106148; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.437 |
| Bcop_0481 | truB | Bcop_0481 | Bcop_0364 | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR015865:IPR015864:IPR002606; KEGG: bfs:BF4147 putative riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SMART: Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; IMG reference gene:2504106148; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.835 |
| guaA | Bcop_0481 | Bcop_0946 | Bcop_0481 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR015865:IPR015864:IPR002606; KEGG: bfs:BF4147 putative riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SMART: Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; IMG reference gene:2504106148; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 0.404 |
| guaA | infB | Bcop_0946 | Bcop_0287 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.801 |
| guaA | nusA | Bcop_0946 | Bcop_0288 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | NusA antitermination factor; Participates in both transcription termination and antitermination. | 0.487 |
| guaA | truB | Bcop_0946 | Bcop_0364 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.910 |
| infB | guaA | Bcop_0287 | Bcop_0946 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.801 |
| infB | nusA | Bcop_0287 | Bcop_0288 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | NusA antitermination factor; Participates in both transcription termination and antitermination. | 0.977 |
| infB | rbfA | Bcop_0287 | Bcop_0426 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.945 |
| infB | truA | Bcop_0287 | Bcop_0773 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.409 |
| infB | truB | Bcop_0287 | Bcop_0364 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.961 |