STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Coexpression
Experiments
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[Homology]
Score
Bcop_03662-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: bfs:BF0071 putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (HppK); PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: Putative uncharacterized protein; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; IMG reference gene:2504106027; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [...] (160 aa)    
Predicted Functional Partners:
Bcop_0557
COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489:IPR006390; KEGG: bvu:BVU_0517 dihydropteroate synthase; PFAM: Pterin-binding; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504106231; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase.
 
 0.999
Bcop_0004
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.997
folE
COGs: COG0302 GTP cyclohydrolase I; HAMAP: GTP cyclohydrolase I; InterPro IPR001474:IPR020602; KEGG: bfs:BF3727 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I; IMG reference gene:2504105794; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I.
 
  
 0.970
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.911
Bcop_1576
NGG1p interacting factor 3 protein, NIF3; COGs: COG3323 conserved hypothetical protein; InterPro IPR002678; KEGG: bfs:BF2473 hypothetical protein; PFAM: NGG1p interacting factor 3, NIF3; SPTR: Putative uncharacterized protein; TIGRFAM: NGG1p interacting factor 3, NIF3; IMG reference gene:2504107291; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: dinuclear metal center protein, YbgI/SA1388 family; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
    
  0.838
queA
S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
  
    0.822
Bcop_1093
FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221:IPR001645; KEGG: bvu:BVU_2328 putative folylpolyglutamate synthase; PFAM: Mur ligase, central; PRIAM: Tetrahydrofolate synthase; SPTR: Folylpolyglutamate synthase; TIGRFAM: Folylpolyglutamate synthetase; IMG reference gene:2504106795; PFAM: Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase.
 
 
 0.773
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
    0.762
Bcop_0362
KEGG: bvu:BVU_1170 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504106023; PFAM: Protein of unknown function (DUF3098).
       0.761
uppP
Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
       0.761
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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