STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bcop_0445DNA protecting protein DprA; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: bfr:BF4562 smf protein DNA processing chain A; PFAM: DNA recombination-mediator protein A; SPTR: Putative DNA processing Smf-like protein; TIGRFAM: DNA recombination-mediator protein A; IMG reference gene:2504106109; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA. (372 aa)    
Predicted Functional Partners:
Bcop_0444
Thioesterase superfamily protein; COGs: COG0824 thioesterase; InterPro IPR006683; KEGG: bth:BT_3071 hypothetical protein; PFAM: Thioesterase superfamily; SPTR: Thioesterase family-like protein; IMG reference gene:2504106108; PFAM: Thioesterase superfamily; TIGRFAM: acyl-CoA thioester hydrolase, YbgC/YbaW family.
  
    0.860
Bcop_0443
Peptidase U32; COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: bfs:BF4351 putative peptidase; PFAM: Peptidase U32; SPTR: Collagenase; IMG reference gene:2504106107; PFAM: Peptidase family U32.
  
    0.846
Bcop_0123
COGs: COG0658 membrane metal-binding protein; InterPro IPR004477; KEGG: bfs:BF3671 putative competence related membrane protein; PFAM: ComEC/Rec2-related protein; SPTR: Putative competence related membrane protein; TIGRFAM: ComEC/Rec2-related protein; IMG reference gene:2504105779; PFAM: Competence protein; TIGRFAM: ComEC/Rec2-related protein.
 
  
 0.826
Bcop_0463
Mg chelatase, subunit ChlI; COGs: COG0606 ATPase with chaperone activity; InterPro IPR003593:IPR000523:IPR004482; KEGG: bth:BT_2846 magnesium chelatase, subunit ChlI; PFAM: Magnesium chelatase, ChlI subunit; SMART: ATPase, AAA+ type, core; SPTR: Putative uncharacterized protein; TIGRFAM: Mg chelatase-related protein; IMG reference gene:2504106130; PFAM: Magnesium chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein.
 
 0.821
Bcop_0435
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: bth:BT_2800 putative amidophosphoribosyl-transferase; PFAM: Phosphoribosyltransferase; SPTR: Predicted amidophosphoribosyltransferases; IMG reference gene:2504106099; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein.
 
 
 0.805
Bcop_0442
TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
       0.611
Bcop_0664
UPF0102 protein yraN; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; HAMAP: Uncharacterised protein family UPF0102; InterPro IPR003509; KEGG: fps:FP0059 hypothetical protein; PFAM: Uncharacterised protein family UPF0102; SPTR: UPF0102 protein FP0059; IMG reference gene:2504106344; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: TIGR00252 family protein.
 
    0.608
Bcop_0892
COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: bfs:BF1571 putative single-strand binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-stranded DNA-binding protein; TIGRFAM: Single-strand DNA-binding; IMG reference gene:2504106587; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb).
 
  
 0.517
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.515
Bcop_0582
UPF0758 protein yicR; COGs: COG2003 DNA repair protein; HAMAP: Uncharacterised protein family UPF0758, YicR subfamily; InterPro IPR022820:IPR001405; KEGG: bfr:BF0483 putative DNA repair protein; PFAM: Uncharacterised protein family UPF0758; SPTR: Putative DNA repair protein; TIGRFAM: Uncharacterised protein family UPF0758; IMG reference gene:2504106256; PFAM: Protein of unknown function (DUF2466); TIGRFAM: DNA repair protein radc; Belongs to the UPF0758 family.
  
  
 0.509
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
Server load: medium (68%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.