STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Bcop_0481Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR015865:IPR015864:IPR002606; KEGG: bfs:BF4147 putative riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SMART: Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; IMG reference gene:2504106148; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. (309 aa)    
Predicted Functional Partners:
Bcop_1153
COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: bth:BT_1317 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; IMG reference gene:2504106856; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit.
  
 
 0.954
Bcop_0480
HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834:IPR006402; KEGG: bfs:BF4148 putative haloacid dehalogenase-type hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Putative haloacid dehalogenase-type hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2504106147; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED.
  
 
 0.905
Bcop_0479
Calcium-translocating P-type ATPase, PMCA-type; COGs: COG0474 Cation transport ATPase; InterProIPR004014:IPR008250:IPR005834:IPR006068:IPR 006408:IPR001757; KEGG: bvu:BVU_1302 putative transmembrane calcium-transporting ATPase; PFAM: ATPase, P-type, ATPase-associated domain; ATPase, P-type cation-transporter, N-terminal; Haloacid dehalogenase-like hydrolase; ATPase, P-type cation-transporter, C-terminal; PRIAM: Calcium-transporting ATPase; SMART: ATPase, P-type cation-transporter, N-terminal; SPTR: Calcium-translocating P-type ATPase, PMCA-type; TIGRFAM: ATPase, P-type, calcium-transpo [...]
       0.844
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
 
  
 0.812
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
  
 0.807
cmk
COGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR003136:IPR011994; KEGG: bth:BT_2060 cytidylate kinase; PFAM: Cytidylate kinase domain; PRIAM: Cytidylate kinase; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase; IMG reference gene:2504105733; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
 
  
 0.772
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.763
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
   
 0.733
Bcop_0600
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
  
 0.696
Bcop_0103
COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: bth:BT_2151 glycosyltransferase; PFAM: Glycosyl transferase, family 2; SPTR: Putative uncharacterized protein; IMG reference gene:2504105759; PFAM: Glycosyl transferase family 2.
      0.630
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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