| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bcop_0319 | Bcop_0625 | Bcop_0319 | Bcop_0625 | COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005856:IPR005859; KEGG: bfs:BF4362 putative cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; IMG reference gene:2504105980; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | 0.953 |
| Bcop_0319 | metG | Bcop_0319 | Bcop_0462 | COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005856:IPR005859; KEGG: bfs:BF4362 putative cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; IMG reference gene:2504105980; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.426 |
| Bcop_0319 | mnmA | Bcop_0319 | Bcop_0169 | COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005856:IPR005859; KEGG: bfs:BF4362 putative cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; IMG reference gene:2504105980; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. | tRNA-specific 2-thiouridylase mnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.464 |
| Bcop_0319 | mnmA-2 | Bcop_0319 | Bcop_0504 | COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005856:IPR005859; KEGG: bfs:BF4362 putative cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; IMG reference gene:2504105980; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. | tRNA-specific 2-thiouridylase mnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.587 |
| Bcop_0481 | mnmA-2 | Bcop_0481 | Bcop_0504 | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR015865:IPR015864:IPR002606; KEGG: bfs:BF4147 putative riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SMART: Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; IMG reference gene:2504106148; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | tRNA-specific 2-thiouridylase mnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.531 |
| Bcop_0505 | Bcop_0506 | Bcop_0505 | Bcop_0506 | Acetyltransferase; COGs: COG0663 Carbonic anhydrase/acetyltransferase isoleucine patch superfamily; InterPro IPR001451; KEGG: bvu:BVU_0829 acetyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106172. | Creatinase; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: bfr:BF4203 putative aminopeptidase; PFAM: Creatinase; Peptidase M24, structural domain; SPTR: Putative aminopeptidase; IMG reference gene:2504106173; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain. | 0.844 |
| Bcop_0505 | mnmA-2 | Bcop_0505 | Bcop_0504 | Acetyltransferase; COGs: COG0663 Carbonic anhydrase/acetyltransferase isoleucine patch superfamily; InterPro IPR001451; KEGG: bvu:BVU_0829 acetyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106172. | tRNA-specific 2-thiouridylase mnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.604 |
| Bcop_0505 | rpsU | Bcop_0505 | Bcop_0508 | Acetyltransferase; COGs: COG0663 Carbonic anhydrase/acetyltransferase isoleucine patch superfamily; InterPro IPR001451; KEGG: bvu:BVU_0829 acetyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106172. | HAMAP: Ribosomal protein S21; InterPro IPR001911; KEGG: bvu:BVU_0827 30S ribosomal protein S21; PFAM: Ribosomal protein S21; SPTR: 30S ribosomal protein S21; TIGRFAM: Ribosomal protein S21; IMG reference gene:2504106175; PFAM: Ribosomal protein S21; TIGRFAM: ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. | 0.707 |
| Bcop_0506 | Bcop_0505 | Bcop_0506 | Bcop_0505 | Creatinase; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: bfr:BF4203 putative aminopeptidase; PFAM: Creatinase; Peptidase M24, structural domain; SPTR: Putative aminopeptidase; IMG reference gene:2504106173; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain. | Acetyltransferase; COGs: COG0663 Carbonic anhydrase/acetyltransferase isoleucine patch superfamily; InterPro IPR001451; KEGG: bvu:BVU_0829 acetyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106172. | 0.844 |
| Bcop_0506 | Bcop_0625 | Bcop_0506 | Bcop_0625 | Creatinase; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: bfr:BF4203 putative aminopeptidase; PFAM: Creatinase; Peptidase M24, structural domain; SPTR: Putative aminopeptidase; IMG reference gene:2504106173; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain. | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | 0.441 |
| Bcop_0506 | mnmA-2 | Bcop_0506 | Bcop_0504 | Creatinase; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: bfr:BF4203 putative aminopeptidase; PFAM: Creatinase; Peptidase M24, structural domain; SPTR: Putative aminopeptidase; IMG reference gene:2504106173; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain. | tRNA-specific 2-thiouridylase mnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.599 |
| Bcop_0506 | rpsU | Bcop_0506 | Bcop_0508 | Creatinase; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: bfr:BF4203 putative aminopeptidase; PFAM: Creatinase; Peptidase M24, structural domain; SPTR: Putative aminopeptidase; IMG reference gene:2504106173; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain. | HAMAP: Ribosomal protein S21; InterPro IPR001911; KEGG: bvu:BVU_0827 30S ribosomal protein S21; PFAM: Ribosomal protein S21; SPTR: 30S ribosomal protein S21; TIGRFAM: Ribosomal protein S21; IMG reference gene:2504106175; PFAM: Ribosomal protein S21; TIGRFAM: ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. | 0.714 |
| Bcop_0625 | Bcop_0319 | Bcop_0625 | Bcop_0319 | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005856:IPR005859; KEGG: bfs:BF4362 putative cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; IMG reference gene:2504105980; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.953 |
| Bcop_0625 | Bcop_0506 | Bcop_0625 | Bcop_0506 | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | Creatinase; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: bfr:BF4203 putative aminopeptidase; PFAM: Creatinase; Peptidase M24, structural domain; SPTR: Putative aminopeptidase; IMG reference gene:2504106173; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain. | 0.441 |
| Bcop_0625 | metG | Bcop_0625 | Bcop_0462 | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.443 |
| Bcop_0625 | mnmA | Bcop_0625 | Bcop_0169 | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | tRNA-specific 2-thiouridylase mnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.633 |
| Bcop_0625 | mnmA-2 | Bcop_0625 | Bcop_0504 | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | tRNA-specific 2-thiouridylase mnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.633 |
| Bcop_0625 | mnmG | Bcop_0625 | Bcop_0347 | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.460 |
| metG | Bcop_0319 | Bcop_0462 | Bcop_0319 | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005856:IPR005859; KEGG: bfs:BF4362 putative cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; IMG reference gene:2504105980; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.426 |
| metG | Bcop_0625 | Bcop_0462 | Bcop_0625 | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | 0.443 |