| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bcop_0450 | Bcop_0560 | Bcop_0450 | Bcop_0560 | KEGG: bvu:BVU_0830 hypothetical protein; SPTR: Putative lipoprotein; IMG reference gene:2504106114; PFAM: OmpW family. | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3649 putative modulator of DNA gyrase; PFAM: Peptidase U62, modulator of DNA gyrase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106234; PFAM: Putative modulator of DNA gyrase. | 0.441 |
| Bcop_0557 | Bcop_0559 | Bcop_0557 | Bcop_0559 | COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489:IPR006390; KEGG: bvu:BVU_0517 dihydropteroate synthase; PFAM: Pterin-binding; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504106231; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3648 putative modulator of DNA gyrase; PFAM: Peptidase U62, modulator of DNA gyrase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106233; PFAM: Putative modulator of DNA gyrase. | 0.732 |
| Bcop_0557 | Bcop_0560 | Bcop_0557 | Bcop_0560 | COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489:IPR006390; KEGG: bvu:BVU_0517 dihydropteroate synthase; PFAM: Pterin-binding; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504106231; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3649 putative modulator of DNA gyrase; PFAM: Peptidase U62, modulator of DNA gyrase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106234; PFAM: Putative modulator of DNA gyrase. | 0.696 |
| Bcop_0557 | dacA | Bcop_0557 | Bcop_0558 | COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489:IPR006390; KEGG: bvu:BVU_0517 dihydropteroate synthase; PFAM: Pterin-binding; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504106231; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | Conserved hypothetical protein CHP00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.753 |
| Bcop_0557 | murF | Bcop_0557 | Bcop_0556 | COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489:IPR006390; KEGG: bvu:BVU_0517 dihydropteroate synthase; PFAM: Pterin-binding; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504106231; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.594 |
| Bcop_0559 | Bcop_0557 | Bcop_0559 | Bcop_0557 | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3648 putative modulator of DNA gyrase; PFAM: Peptidase U62, modulator of DNA gyrase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106233; PFAM: Putative modulator of DNA gyrase. | COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489:IPR006390; KEGG: bvu:BVU_0517 dihydropteroate synthase; PFAM: Pterin-binding; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504106231; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | 0.732 |
| Bcop_0559 | Bcop_0560 | Bcop_0559 | Bcop_0560 | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3648 putative modulator of DNA gyrase; PFAM: Peptidase U62, modulator of DNA gyrase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106233; PFAM: Putative modulator of DNA gyrase. | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3649 putative modulator of DNA gyrase; PFAM: Peptidase U62, modulator of DNA gyrase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106234; PFAM: Putative modulator of DNA gyrase. | 0.840 |
| Bcop_0559 | dacA | Bcop_0559 | Bcop_0558 | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3648 putative modulator of DNA gyrase; PFAM: Peptidase U62, modulator of DNA gyrase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106233; PFAM: Putative modulator of DNA gyrase. | Conserved hypothetical protein CHP00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.796 |
| Bcop_0559 | murF | Bcop_0559 | Bcop_0556 | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3648 putative modulator of DNA gyrase; PFAM: Peptidase U62, modulator of DNA gyrase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106233; PFAM: Putative modulator of DNA gyrase. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.503 |
| Bcop_0560 | Bcop_0450 | Bcop_0560 | Bcop_0450 | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3649 putative modulator of DNA gyrase; PFAM: Peptidase U62, modulator of DNA gyrase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106234; PFAM: Putative modulator of DNA gyrase. | KEGG: bvu:BVU_0830 hypothetical protein; SPTR: Putative lipoprotein; IMG reference gene:2504106114; PFAM: OmpW family. | 0.441 |
| Bcop_0560 | Bcop_0557 | Bcop_0560 | Bcop_0557 | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3649 putative modulator of DNA gyrase; PFAM: Peptidase U62, modulator of DNA gyrase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106234; PFAM: Putative modulator of DNA gyrase. | COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489:IPR006390; KEGG: bvu:BVU_0517 dihydropteroate synthase; PFAM: Pterin-binding; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504106231; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | 0.696 |
| Bcop_0560 | Bcop_0559 | Bcop_0560 | Bcop_0559 | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3649 putative modulator of DNA gyrase; PFAM: Peptidase U62, modulator of DNA gyrase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106234; PFAM: Putative modulator of DNA gyrase. | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3648 putative modulator of DNA gyrase; PFAM: Peptidase U62, modulator of DNA gyrase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106233; PFAM: Putative modulator of DNA gyrase. | 0.840 |
| Bcop_0560 | dacA | Bcop_0560 | Bcop_0558 | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3649 putative modulator of DNA gyrase; PFAM: Peptidase U62, modulator of DNA gyrase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106234; PFAM: Putative modulator of DNA gyrase. | Conserved hypothetical protein CHP00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.754 |
| Bcop_0560 | murF | Bcop_0560 | Bcop_0556 | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3649 putative modulator of DNA gyrase; PFAM: Peptidase U62, modulator of DNA gyrase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106234; PFAM: Putative modulator of DNA gyrase. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.473 |
| dacA | Bcop_0557 | Bcop_0558 | Bcop_0557 | Conserved hypothetical protein CHP00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489:IPR006390; KEGG: bvu:BVU_0517 dihydropteroate synthase; PFAM: Pterin-binding; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504106231; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | 0.753 |
| dacA | Bcop_0559 | Bcop_0558 | Bcop_0559 | Conserved hypothetical protein CHP00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3648 putative modulator of DNA gyrase; PFAM: Peptidase U62, modulator of DNA gyrase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106233; PFAM: Putative modulator of DNA gyrase. | 0.796 |
| dacA | Bcop_0560 | Bcop_0558 | Bcop_0560 | Conserved hypothetical protein CHP00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3649 putative modulator of DNA gyrase; PFAM: Peptidase U62, modulator of DNA gyrase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106234; PFAM: Putative modulator of DNA gyrase. | 0.754 |
| dacA | murF | Bcop_0558 | Bcop_0556 | Conserved hypothetical protein CHP00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.561 |
| murF | Bcop_0557 | Bcop_0556 | Bcop_0557 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489:IPR006390; KEGG: bvu:BVU_0517 dihydropteroate synthase; PFAM: Pterin-binding; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504106231; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | 0.594 |
| murF | Bcop_0559 | Bcop_0556 | Bcop_0559 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3648 putative modulator of DNA gyrase; PFAM: Peptidase U62, modulator of DNA gyrase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106233; PFAM: Putative modulator of DNA gyrase. | 0.503 |