STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (260 aa)    
Predicted Functional Partners:
Bcop_0774
Protein of unknown function DUF6 transmembrane; InterPro IPR000620; KEGG: bth:BT_4238 putative permease; PFAM: Drug/metabolite transporter; SPTR: Permease; IMG reference gene:2504106462; PFAM: EamA-like transporter family.
       0.779
Bcop_0775
KEGG: bth:BT_4239 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504106463; PFAM: Protein of unknown function (DUF3256).
       0.779
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.773
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
 
 0.726
rplQ
COGs: COG0203 Ribosomal protein L17; HAMAP: Ribosomal protein L17; InterPro IPR000456; KEGG: bfs:BF3975 50S ribosomal protein L17; PFAM: Ribosomal protein L17; SPTR: 50S ribosomal protein L17; TIGRFAM: Ribosomal protein L17; IMG reference gene:2504105874; PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17.
  
  
 0.718
Bcop_0625
CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...]
   
 
 0.588
rsmH
Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
   
 
 0.585
Bcop_1298
Beta-lactamase domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279; KEGG: bfr:BF2026 putative metallo-beta-lactamase; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: Putative metallo-beta-lactamase; IMG reference gene:2504107005; PFAM: Metallo-beta-lactamase superfamily.
   
 
 0.551
ybeY
Metalloprotease ybeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
   0.549
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.546
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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