STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (189 aa)    
Predicted Functional Partners:
Bcop_0781
COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR000836:IPR005904; KEGG: bfs:BF1031 putative hypoxanthine guanine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Putative hypoxanthine guanine phosphoribosyltransferase; TIGRFAM: Hypoxanthine phosphoribosyl transferase; IMG reference gene:2504106469; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 
 0.989
Bcop_0181
COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR022761:IPR013539; KEGG: bfs:BF3792 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal/plant; Lyase 1, N-terminal; PRIAM: Adenylosuccinate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504105838; PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
 0.961
Bcop_1354
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
     
 0.921
Bcop_0145
COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: bfs:BF3733 nucleoside diphosphate kinase; PFAM: Nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: Nucleoside diphosphate kinase; SPTR: Nucleoside diphosphate kinase; IMG reference gene:2504105801; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family.
  
 0.917
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.906
Bcop_1355
Ribonucleotide reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
     
 0.903
Bcop_0428
COGs: COG0469 Pyruvate kinase; InterPro IPR015793:IPR015795:IPR001697; KEGG: bfs:BF4277 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase; IMG reference gene:2504106091; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.899
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.899
Bcop_0002
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
     
 0.891
Bcop_0641
COGs: COG1564 Thiamine pyrophosphokinase; InterPro IPR007371:IPR006282; KEGG: bth:BT_2397 hypothetical protein; PFAM: Thiamin pyrophosphokinase, catalytic domain; SPTR: Putative uncharacterized protein; TIGRFAM: Thiamin pyrophosphokinase; IMG reference gene:2504106320; PFAM: Thiamin pyrophosphokinase, catalytic domain; TIGRFAM: thiamine pyrophosphokinase.
     
 0.881
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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