| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bcop_0193 | Bcop_0837 | Bcop_0193 | Bcop_0837 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: bth:BT_3866 glutamine-dependent carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Glutamine-dependent carbamyl phosphate synthetase; TIGRFAM: Carbamoy [...] | Allantoinase; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680; KEGG: bth:BT_0250 dihydroorotase; PFAM: Amidohydrolase 1; PRIAM: Allantoinase; SPTR: Dihydroorotase; IMG reference gene:2504106526; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type. | 0.986 |
| Bcop_0193 | Bcop_0971 | Bcop_0193 | Bcop_0971 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: bth:BT_3866 glutamine-dependent carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Glutamine-dependent carbamyl phosphate synthetase; TIGRFAM: Carbamoy [...] | COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043; KEGG: drm:Dred_1236 xanthine/uracil/vitamin C permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Xanthine/uracil/vitamin C permease; IMG reference gene:2504106672; PFAM: Permease family. | 0.548 |
| Bcop_0193 | Bcop_1564 | Bcop_0193 | Bcop_1564 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: bth:BT_3866 glutamine-dependent carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Glutamine-dependent carbamyl phosphate synthetase; TIGRFAM: Carbamoy [...] | Oxidoreductase FAD/NAD(P)-binding domain protein; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR008333:IPR001433:IPR019480; KEGG: bth:BT_0891 dihydroorotate dehydrogenase electron transfer subunit; PFAM: Oxidoreductase FAD/NAD(P)-binding; Oxidoreductase, FAD-binding domain; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: Putative dihydroorotate dehydrogenase; IMG reference gene:2504107279; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate deh [...] | 0.908 |
| Bcop_0193 | Bcop_1660 | Bcop_0193 | Bcop_1660 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: bth:BT_3866 glutamine-dependent carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Glutamine-dependent carbamyl phosphate synthetase; TIGRFAM: Carbamoy [...] | COGs: COG2233 Xanthine/uracil permease; InterPro IPR006042:IPR017588:IPR006043; KEGG: bvu:BVU_2531 putative purine permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Putative uncharacterized protein; TIGRFAM: Xanthine permease; Xanthine/uracil permease; IMG reference gene:2504107376; PFAM: Permease family; TIGRFAM: uracil-xanthine permease; xanthine permease. | 0.548 |
| Bcop_0193 | purL | Bcop_0193 | Bcop_2375 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: bth:BT_3866 glutamine-dependent carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Glutamine-dependent carbamyl phosphate synthetase; TIGRFAM: Carbamoy [...] | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.852 |
| Bcop_0193 | pyrB | Bcop_0193 | Bcop_2029 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: bth:BT_3866 glutamine-dependent carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Glutamine-dependent carbamyl phosphate synthetase; TIGRFAM: Carbamoy [...] | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase, eukaryotic; InterPro IPR002082:IPR006132:IPR006131; KEGG: bth:BT_0742 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; IMG reference gene:2504107748; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; [...] | 0.999 |
| Bcop_0193 | pyrE | Bcop_0193 | Bcop_0603 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: bth:BT_3866 glutamine-dependent carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Glutamine-dependent carbamyl phosphate synthetase; TIGRFAM: Carbamoy [...] | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.856 |
| Bcop_0193 | pyrF | Bcop_0193 | Bcop_0756 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: bth:BT_3866 glutamine-dependent carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Glutamine-dependent carbamyl phosphate synthetase; TIGRFAM: Carbamoy [...] | COGs: COG0284 Orotidine-5'-phosphate decarboxylase; HAMAP: Orotidine 5'-phosphate decarboxylase, type 2; InterPro IPR001754:IPR011995; KEGG: bth:BT_4209 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase domain; PRIAM: Orotidine-5'-phosphate decarboxylase; SMART: Orotidine 5'-phosphate decarboxylase domain; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: Orotidine 5'-phosphate decarboxylase, type 2; IMG reference gene:2504106444; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belo [...] | 0.842 |
| Bcop_0837 | Bcop_0193 | Bcop_0837 | Bcop_0193 | Allantoinase; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680; KEGG: bth:BT_0250 dihydroorotase; PFAM: Amidohydrolase 1; PRIAM: Allantoinase; SPTR: Dihydroorotase; IMG reference gene:2504106526; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type. | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: bth:BT_3866 glutamine-dependent carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Glutamine-dependent carbamyl phosphate synthetase; TIGRFAM: Carbamoy [...] | 0.986 |
| Bcop_0837 | Bcop_0971 | Bcop_0837 | Bcop_0971 | Allantoinase; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680; KEGG: bth:BT_0250 dihydroorotase; PFAM: Amidohydrolase 1; PRIAM: Allantoinase; SPTR: Dihydroorotase; IMG reference gene:2504106526; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type. | COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043; KEGG: drm:Dred_1236 xanthine/uracil/vitamin C permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Xanthine/uracil/vitamin C permease; IMG reference gene:2504106672; PFAM: Permease family. | 0.596 |
| Bcop_0837 | Bcop_1564 | Bcop_0837 | Bcop_1564 | Allantoinase; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680; KEGG: bth:BT_0250 dihydroorotase; PFAM: Amidohydrolase 1; PRIAM: Allantoinase; SPTR: Dihydroorotase; IMG reference gene:2504106526; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type. | Oxidoreductase FAD/NAD(P)-binding domain protein; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR008333:IPR001433:IPR019480; KEGG: bth:BT_0891 dihydroorotate dehydrogenase electron transfer subunit; PFAM: Oxidoreductase FAD/NAD(P)-binding; Oxidoreductase, FAD-binding domain; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: Putative dihydroorotate dehydrogenase; IMG reference gene:2504107279; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate deh [...] | 0.986 |
| Bcop_0837 | Bcop_1660 | Bcop_0837 | Bcop_1660 | Allantoinase; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680; KEGG: bth:BT_0250 dihydroorotase; PFAM: Amidohydrolase 1; PRIAM: Allantoinase; SPTR: Dihydroorotase; IMG reference gene:2504106526; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type. | COGs: COG2233 Xanthine/uracil permease; InterPro IPR006042:IPR017588:IPR006043; KEGG: bvu:BVU_2531 putative purine permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Putative uncharacterized protein; TIGRFAM: Xanthine permease; Xanthine/uracil permease; IMG reference gene:2504107376; PFAM: Permease family; TIGRFAM: uracil-xanthine permease; xanthine permease. | 0.596 |
| Bcop_0837 | purL | Bcop_0837 | Bcop_2375 | Allantoinase; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680; KEGG: bth:BT_0250 dihydroorotase; PFAM: Amidohydrolase 1; PRIAM: Allantoinase; SPTR: Dihydroorotase; IMG reference gene:2504106526; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.601 |
| Bcop_0837 | pyrB | Bcop_0837 | Bcop_2029 | Allantoinase; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680; KEGG: bth:BT_0250 dihydroorotase; PFAM: Amidohydrolase 1; PRIAM: Allantoinase; SPTR: Dihydroorotase; IMG reference gene:2504106526; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type. | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase, eukaryotic; InterPro IPR002082:IPR006132:IPR006131; KEGG: bth:BT_0742 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; IMG reference gene:2504107748; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; [...] | 0.999 |
| Bcop_0837 | pyrE | Bcop_0837 | Bcop_0603 | Allantoinase; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680; KEGG: bth:BT_0250 dihydroorotase; PFAM: Amidohydrolase 1; PRIAM: Allantoinase; SPTR: Dihydroorotase; IMG reference gene:2504106526; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.930 |
| Bcop_0837 | pyrF | Bcop_0837 | Bcop_0756 | Allantoinase; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680; KEGG: bth:BT_0250 dihydroorotase; PFAM: Amidohydrolase 1; PRIAM: Allantoinase; SPTR: Dihydroorotase; IMG reference gene:2504106526; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type. | COGs: COG0284 Orotidine-5'-phosphate decarboxylase; HAMAP: Orotidine 5'-phosphate decarboxylase, type 2; InterPro IPR001754:IPR011995; KEGG: bth:BT_4209 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase domain; PRIAM: Orotidine-5'-phosphate decarboxylase; SMART: Orotidine 5'-phosphate decarboxylase domain; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: Orotidine 5'-phosphate decarboxylase, type 2; IMG reference gene:2504106444; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belo [...] | 0.842 |
| Bcop_0970 | Bcop_0971 | Bcop_0970 | Bcop_0971 | COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910:IPR000531; KEGG: bfr:BF0601 putative TonB-dependent outer membrane protein; PFAM: TonB-dependent receptor, beta-barrel; TonB-dependent receptor, plug; SPTR: Putative TonB-dependent outer membrane protein; IMG reference gene:2504106671; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor. | COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043; KEGG: drm:Dred_1236 xanthine/uracil/vitamin C permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Xanthine/uracil/vitamin C permease; IMG reference gene:2504106672; PFAM: Permease family. | 0.570 |
| Bcop_0971 | Bcop_0193 | Bcop_0971 | Bcop_0193 | COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043; KEGG: drm:Dred_1236 xanthine/uracil/vitamin C permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Xanthine/uracil/vitamin C permease; IMG reference gene:2504106672; PFAM: Permease family. | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: bth:BT_3866 glutamine-dependent carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Glutamine-dependent carbamyl phosphate synthetase; TIGRFAM: Carbamoy [...] | 0.548 |
| Bcop_0971 | Bcop_0837 | Bcop_0971 | Bcop_0837 | COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043; KEGG: drm:Dred_1236 xanthine/uracil/vitamin C permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Xanthine/uracil/vitamin C permease; IMG reference gene:2504106672; PFAM: Permease family. | Allantoinase; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680; KEGG: bth:BT_0250 dihydroorotase; PFAM: Amidohydrolase 1; PRIAM: Allantoinase; SPTR: Dihydroorotase; IMG reference gene:2504106526; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type. | 0.596 |
| Bcop_0971 | Bcop_0970 | Bcop_0971 | Bcop_0970 | COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043; KEGG: drm:Dred_1236 xanthine/uracil/vitamin C permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Xanthine/uracil/vitamin C permease; IMG reference gene:2504106672; PFAM: Permease family. | COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910:IPR000531; KEGG: bfr:BF0601 putative TonB-dependent outer membrane protein; PFAM: TonB-dependent receptor, beta-barrel; TonB-dependent receptor, plug; SPTR: Putative TonB-dependent outer membrane protein; IMG reference gene:2504106671; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor. | 0.570 |