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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bcop_1007COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR001341; KEGG: bth:BT_1375 aspartokinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Putative uncharacterized protein; TIGRFAM: Aspartate kinase domain; IMG reference gene:2504106709; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. (440 aa)    
Predicted Functional Partners:
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 
 0.977
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 0.975
Bcop_0611
COGs: COG0137 Argininosuccinate synthase; InterPro IPR001518; KEGG: aps:CFPG_348 argininosuccinate synthase; PFAM: Argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; IMG reference gene:2504106288; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase.
 
 
 0.910
Bcop_0948
L-asparaginase, type I; COGs: COG0252 L-asparaginase/ Glu-tRNAGln amidotransferase subunit D; InterPro IPR006034:IPR006033; KEGG: bfs:BF2680 putative L-asparaginase I; PFAM: Asparaginase/glutaminase; PRIAM: 1-alkyl-2-acetylglycerophosphocholine esterase; SMART: Asparaginase/glutaminase; SPTR: Putative L-asparaginase I; TIGRFAM: L-asparaginase, type I; IMG reference gene:2504106649; PFAM: Asparaginase; TIGRFAM: L-asparaginases, type I.
  
  
 0.893
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
   
 
  0.889
Bcop_1325
COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: bth:BT_2415 aspartate aminotransferase; PFAM: Aminotransferase, class I/classII; PRIAM: Aspartate transaminase; SPTR: Aspartate aminotransferase; IMG reference gene:2504107033; PFAM: Aminotransferase class I and II.
  
 
 0.889
Bcop_2236
COGs: COG1027 Aspartate ammonia-lyase; InterPro IPR022761:IPR018951; KEGG: bfs:BF4037 aspartate ammonia-lyase; PFAM: Lyase 1, N-terminal; Fumarase C, C-terminal; PRIAM: Aspartate ammonia-lyase; SPTR: Putative uncharacterized protein; IMG reference gene:2504107957; PFAM: Fumarase C C-terminus; Lyase; TIGRFAM: aspartate ammonia-lyase.
     
 0.877
hisI
Phosphoribosyl-ATP pyrophosphatase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit; In the C-terminal section; belongs to the PRA-PH family.
  
  
 0.805
Bcop_1006
COGs: COG2884 ATPase involved in cell division; InterPro IPR003593:IPR003439; KEGG: bvu:BVU_3855 putative ATP-binding protein involved in cell division; PFAM: ABC transporter-like; PRIAM: Fe(3+)-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Putative ATP-binding protein involved in cell division; IMG reference gene:2504106708; PFAM: ABC transporter.
       0.760
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
 0.746
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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