| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bcop_0181 | Bcop_0193 | Bcop_0181 | Bcop_0193 | COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR022761:IPR013539; KEGG: bfs:BF3792 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal/plant; Lyase 1, N-terminal; PRIAM: Adenylosuccinate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504105838; PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: bth:BT_3866 glutamine-dependent carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Glutamine-dependent carbamyl phosphate synthetase; TIGRFAM: Carbamoy [...] | 0.557 |
| Bcop_0181 | Bcop_0758 | Bcop_0181 | Bcop_0758 | COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR022761:IPR013539; KEGG: bfs:BF3792 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal/plant; Lyase 1, N-terminal; PRIAM: Adenylosuccinate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504105838; PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine cyclo-ligase; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918; KEGG: bvu:BVU_0092 putative phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase-related protein, C-terminal; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106446; PFAM: AIR synthase related protein, C-terminal domain. | 0.990 |
| Bcop_0181 | Bcop_1027 | Bcop_0181 | Bcop_1027 | COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR022761:IPR013539; KEGG: bfs:BF3792 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal/plant; Lyase 1, N-terminal; PRIAM: Adenylosuccinate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504105838; PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: bfs:BF2659 putative phosphoribosylpyrophosphate amidotransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106729. | 0.991 |
| Bcop_0181 | Bcop_2008 | Bcop_0181 | Bcop_2008 | COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR022761:IPR013539; KEGG: bfs:BF3792 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal/plant; Lyase 1, N-terminal; PRIAM: Adenylosuccinate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504105838; PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR005946:IPR000836; KEGG: bth:BT_0748 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase; IMG reference gene:2504107727; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | 0.504 |
| Bcop_0181 | purC | Bcop_0181 | Bcop_0765 | COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR022761:IPR013539; KEGG: bfs:BF3792 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal/plant; Lyase 1, N-terminal; PRIAM: Adenylosuccinate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504105838; PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; HAMAP: SAICAR synthetase; InterPro IPR001636; KEGG: pgn:PGN_0976 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: Phosphoribosylaminoimidazole-succinocarboxamide synthase; IMG reference gene:2504106453; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. | 0.998 |
| Bcop_0181 | purD | Bcop_0181 | Bcop_0323 | COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR022761:IPR013539; KEGG: bfs:BF3792 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal/plant; Lyase 1, N-terminal; PRIAM: Adenylosuccinate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504105838; PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | COGs: COG0151 Phosphoribosylamine-glycine ligase; HAMAP: Phosphoribosylglycinamide synthetase; InterPro IPR000115:IPR020562:IPR020561:IPR020560; KEGG: bth:BT_3253 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: Phosphoribosylamine--glycine ligase; TIGRFAM: Phosphoribosylglycinamide synthetase; IMG reference gene:2504105984; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribo [...] | 0.986 |
| Bcop_0181 | purE | Bcop_0181 | Bcop_0495 | COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR022761:IPR013539; KEGG: bfs:BF3792 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal/plant; Lyase 1, N-terminal; PRIAM: Adenylosuccinate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504105838; PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.993 |
| Bcop_0181 | purL | Bcop_0181 | Bcop_2375 | COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR022761:IPR013539; KEGG: bfs:BF3792 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal/plant; Lyase 1, N-terminal; PRIAM: Adenylosuccinate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504105838; PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.995 |
| Bcop_0181 | purN | Bcop_0181 | Bcop_0385 | COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR022761:IPR013539; KEGG: bfs:BF3792 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal/plant; Lyase 1, N-terminal; PRIAM: Adenylosuccinate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504105838; PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.941 |
| Bcop_0193 | Bcop_0181 | Bcop_0193 | Bcop_0181 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: bth:BT_3866 glutamine-dependent carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Glutamine-dependent carbamyl phosphate synthetase; TIGRFAM: Carbamoy [...] | COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR022761:IPR013539; KEGG: bfs:BF3792 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal/plant; Lyase 1, N-terminal; PRIAM: Adenylosuccinate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504105838; PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.557 |
| Bcop_0193 | Bcop_0758 | Bcop_0193 | Bcop_0758 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: bth:BT_3866 glutamine-dependent carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Glutamine-dependent carbamyl phosphate synthetase; TIGRFAM: Carbamoy [...] | Phosphoribosylformylglycinamidine cyclo-ligase; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918; KEGG: bvu:BVU_0092 putative phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase-related protein, C-terminal; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106446; PFAM: AIR synthase related protein, C-terminal domain. | 0.412 |
| Bcop_0193 | Bcop_1027 | Bcop_0193 | Bcop_1027 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: bth:BT_3866 glutamine-dependent carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Glutamine-dependent carbamyl phosphate synthetase; TIGRFAM: Carbamoy [...] | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: bfs:BF2659 putative phosphoribosylpyrophosphate amidotransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106729. | 0.955 |
| Bcop_0193 | purD | Bcop_0193 | Bcop_0323 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: bth:BT_3866 glutamine-dependent carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Glutamine-dependent carbamyl phosphate synthetase; TIGRFAM: Carbamoy [...] | COGs: COG0151 Phosphoribosylamine-glycine ligase; HAMAP: Phosphoribosylglycinamide synthetase; InterPro IPR000115:IPR020562:IPR020561:IPR020560; KEGG: bth:BT_3253 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: Phosphoribosylamine--glycine ligase; TIGRFAM: Phosphoribosylglycinamide synthetase; IMG reference gene:2504105984; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribo [...] | 0.623 |
| Bcop_0193 | purE | Bcop_0193 | Bcop_0495 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: bth:BT_3866 glutamine-dependent carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Glutamine-dependent carbamyl phosphate synthetase; TIGRFAM: Carbamoy [...] | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.475 |
| Bcop_0193 | purL | Bcop_0193 | Bcop_2375 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: bth:BT_3866 glutamine-dependent carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Glutamine-dependent carbamyl phosphate synthetase; TIGRFAM: Carbamoy [...] | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.899 |
| Bcop_0193 | purN | Bcop_0193 | Bcop_0385 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: bth:BT_3866 glutamine-dependent carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Glutamine-dependent carbamyl phosphate synthetase; TIGRFAM: Carbamoy [...] | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.494 |
| Bcop_0286 | Bcop_0758 | Bcop_0286 | Bcop_0758 | Colicin V production protein; InterPro IPR003825; KEGG: bth:BT_3405 hypothetical protein; PFAM: Colicin V production, CvpA; SPTR: Colicin V production protein; IMG reference gene:2504105947; PFAM: Colicin V production protein. | Phosphoribosylformylglycinamidine cyclo-ligase; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918; KEGG: bvu:BVU_0092 putative phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase-related protein, C-terminal; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106446; PFAM: AIR synthase related protein, C-terminal domain. | 0.829 |
| Bcop_0286 | Bcop_1027 | Bcop_0286 | Bcop_1027 | Colicin V production protein; InterPro IPR003825; KEGG: bth:BT_3405 hypothetical protein; PFAM: Colicin V production, CvpA; SPTR: Colicin V production protein; IMG reference gene:2504105947; PFAM: Colicin V production protein. | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: bfs:BF2659 putative phosphoribosylpyrophosphate amidotransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106729. | 0.913 |
| Bcop_0286 | purC | Bcop_0286 | Bcop_0765 | Colicin V production protein; InterPro IPR003825; KEGG: bth:BT_3405 hypothetical protein; PFAM: Colicin V production, CvpA; SPTR: Colicin V production protein; IMG reference gene:2504105947; PFAM: Colicin V production protein. | COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; HAMAP: SAICAR synthetase; InterPro IPR001636; KEGG: pgn:PGN_0976 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: Phosphoribosylaminoimidazole-succinocarboxamide synthase; IMG reference gene:2504106453; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. | 0.803 |
| Bcop_0286 | purD | Bcop_0286 | Bcop_0323 | Colicin V production protein; InterPro IPR003825; KEGG: bth:BT_3405 hypothetical protein; PFAM: Colicin V production, CvpA; SPTR: Colicin V production protein; IMG reference gene:2504105947; PFAM: Colicin V production protein. | COGs: COG0151 Phosphoribosylamine-glycine ligase; HAMAP: Phosphoribosylglycinamide synthetase; InterPro IPR000115:IPR020562:IPR020561:IPR020560; KEGG: bth:BT_3253 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: Phosphoribosylamine--glycine ligase; TIGRFAM: Phosphoribosylglycinamide synthetase; IMG reference gene:2504105984; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribo [...] | 0.446 |