Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Bcop_1102Export-related chaperone CsaA; COGs: COG0073 EMAP domain; InterPro IPR002547:IPR008231; KEGG: chu:CHU_3785 methionine--tRNA ligase (methionine tRNA synthetase); PFAM: tRNA-binding domain; SPTR: Methionine--tRNA ligase (Methionine tRNA synthetase); TIGRFAM: Secretion chaperone CsaA; IMG reference gene:2504106804; PFAM: Putative tRNA binding domain; TIGRFAM: methionyl-tRNA synthetase C-terminal region/beta chain; export-related chaperone CsaA. (110 aa)    
Predicted Functional Partners:
pheS
COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; HAMAP: Phenylalanyl-tRNA synthetase alpha chain 1, bacterial; InterPro IPR004529:IPR004188:IPR002319:IPR022911; KEGG: bth:BT_1669 phenylalanyl-tRNA synthetase subunit alpha; PFAM: Phenylalanyl-tRNA synthetase; Phenylalanyl-tRNA synthetase, class II, N-terminal; SPTR: Phenylalanyl-tRNA synthetase alpha chain; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, alpha subunit; IMG reference gene:2504107960; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tR [...]
  
 0.904
Bcop_1101
Hypothetical protein; KEGG: fnu:FN0180 TPR repeat-containing protein; SPTR: Tetratricopeptide repeat family protein; IMG reference gene:2504106803.
       0.574
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.526
Bcop_0680
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
  0.521
Bcop_0836
KEGG: bth:BT_0249 5-methyltetrahydrofolate--homocysteine methyltransferase or methionine synthase; SPTR: 5-methyltetrahydrofolate--homocysteine methyltransferase or methionine synthase; IMG reference gene:2504106525.
     
  0.521
Bcop_1103
Protein of unknown function DUF1731; COGs: COG1090 nucleoside-diphosphate sugar epimerase; InterPro IPR008030:IPR013549:IPR010099; KEGG: lip:LI0081 nucleoside-diphosphate sugar epimerase; PFAM: Domain of unknown function DUF1731, C-terminal; NmrA-like; SPTR: Predicted nucleoside-diphosphate sugar epimerase; IMG reference gene:2504106805; PFAM: NAD dependent epimerase/dehydratase family; Domain of unknown function (DUF1731); TIGRFAM: TIGR01777 family protein.
       0.470
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.454
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 
 0.430
secD
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
 
 0.409
Bcop_1100
KEGG: pph:Ppha_1411 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504106802.
       0.407
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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