STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Bcop_1206Nicotinate-nucleotide/dimethylbenzimidazolephosp horibosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (346 aa)    
Predicted Functional Partners:
Bcop_1207
Adenosylcobinamide-phosphateguanylyltransferase; COGs: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; InterPro IPR003203; KEGG: bvu:BVU_3151 cobinamide kinase; PFAM: Cobinamide kinase/cobinamide phosphate guanyltransferase; PRIAM: Adenosylcobinamide-phosphate guanylyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106910; PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase.
 
 0.995
Bcop_1204
COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078:IPR017578; KEGG: pdi:BDI_3954 phosphoglycerate mutase; PFAM: Histidine phosphatase superfamily, clade-1; SMART: Histidine phosphatase superfamily, clade-1; SPTR: Putative uncharacterized protein; TIGRFAM: Alpha-ribazole phosphatase, CobC; IMG reference gene:2504106907; PFAM: Phosphoglycerate mutase family; TIGRFAM: alpha-ribazole phosphatase.
 
 
 0.994
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
 
 0.987
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.970
cobD
Cobalamin biosynthesis protein cbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.958
Bcop_1208
COGs: COG2875 Precorrin-4 methylase; InterPro IPR002750:IPR000878:IPR006362; KEGG: bvu:BVU_3081 precorrin-4 C11-methyltransferase; PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; Tetrapyrrole methylase; PRIAM: Precorrin-4 C(11)-methyltransferase; SPTR: Precorrin-4 C11-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; IMG reference gene:2504106911; PFAM: Cobalamin biosynthesis central region; Cobalamin synthesis G C-terminus; Tetrapyrrole (Corrin/Porphyrin) Methylases; Cobalamin synthesis G N-terminal; TIGRFAM: pr [...]
 
  
 0.957
Bcop_1213
COGs: COG1010 Precorrin-3B methylase; InterPro IPR000878:IPR003722:IPR006363; KEGG: pdi:BDI_1067 precorrin-3B C17-methyltransferase; PFAM: Tetrapyrrole methylase; Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; PRIAM: Precorrin-3B C(17)-methyltransferase., Precorrin-8X methylmutase; SPTR: Precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; IMG reference gene:2504106916; PFAM: Precorrin-8X methylmutase; Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17- [...]
 
  
 0.944
cbiA
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.934
Bcop_1209
Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR012818:IPR014008; KEGG: bvu:BVU_3082 decarboxylating precorrin-6y C5,15-methyltransferase; PRIAM: Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); SPTR: Decarboxylating precorrin-6y C5,15-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core; Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core; IMG reference gene:2504106912; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIG [...]
 
  
 0.926
Bcop_1211
Threonine-phosphate decarboxylase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839; KEGG: bfr:BF2490 aminotransferase; PFAM: Aminotransferase, class I/classII; PRIAM: Threonine-phosphate decarboxylase; SPTR: Aminotransferase involved in cobalamin biosynthesis CobC; IMG reference gene:2504106914; PFAM: Aminotransferase class I and II.
 
  
 0.919
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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