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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Bcop_1979Gluconate 5-dehydrogenase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: cpy:Cphy_2534 gluconate 5-dehydrogenase; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: Gluconate 5-dehydrogenase; SPTR: Gluconate 5-dehydrogenase; IMG reference gene:2504107695; PFAM: short chain dehydrogenase. (260 aa)    
Predicted Functional Partners:
kduI-2
4-deoxy-L-threo-5-hexosulose-uronateketol- isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
 
 0.954
Bcop_2386
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: bth:BT_1747 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain; SPTR: Pyru [...]
   
 0.923
Bcop_0427
COGs: COG4122 O-methyltransferase; InterPro IPR002935; KEGG: bfs:BF4276 putative O-methyltransferase; PFAM: O-methyltransferase, family 3; PRIAM: Caffeoyl-CoA O-methyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106090; PFAM: O-methyltransferase.
 
  
 
 0.894
Bcop_1980
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: pdi:BDI_3186 putative gluconate kinase; PFAM: Carbohydrate/purine kinase; SPTR: Putative uncharacterized protein; IMG reference gene:2504107696; PFAM: pfkB family carbohydrate kinase.
 
 0.891
Bcop_2439
NADH-ubiquinone oxidoreductase chain 49kDa; COGs: COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7; InterPro IPR001268:IPR001135; KEGG: bvu:BVU_1757 NADH dehydrogenase I, chain D; PFAM: NADH-quinone oxidoreductase, subunit D; NADH:ubiquinone oxidoreductase, 30kDa subunit; SPTR: Putative uncharacterized protein; IMG reference gene:2504108171; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit.
   
 
 0.885
Bcop_1978
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: pdi:BDI_3185 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; PFAM: KDPG/KHG aldolase; SPTR: Putative uncharacterized protein; TIGRFAM: KDPG/KHG aldolase; IMG reference gene:2504107694; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase.
 
  
 0.857
kduI
4-deoxy-L-threo-5-hexosulose-uronateketol- isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
 
 0.845
Bcop_1977
COGs: COG3775 Phosphotransferase system galactitol-specific IIC component; InterPro IPR004703; KEGG: bvu:BVU_1796 putative phosphotransferase enzyme II, C component; PFAM: Phosphotransferase system, sugar-specific permease component; SPTR: Putative phosphotransferase enzyme II, C component; IMG reference gene:2504107693; PFAM: PTS system sugar-specific permease component.
  
 
  0.828
fabZ
(3R)-hydroxymyristoyl-(acyl-carrier- protein)dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
  
 
 0.817
Bcop_0535
D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: bfs:BF0370 putative FAD-binding oxidoreductase; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Putative uncharacterized protein; IMG reference gene:2504106209; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain.
   
 0.759
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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