| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bcop_0205 | Bcop_2008 | Bcop_0205 | Bcop_2008 | Trigger factor; COGs: COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); InterPro IPR005215:IPR008881; KEGG: bfs:BF3895 putative cell division trigger factor; PFAM: Trigger factor, ribosome-binding, bacterial; SPTR: FKBP-type peptidyl-prolyl cis-transisomerase; TIGRFAM: Trigger factor; IMG reference gene:2504105864; PFAM: Bacterial trigger factor protein (TF); TIGRFAM: trigger factor. | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR005946:IPR000836; KEGG: bth:BT_0748 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase; IMG reference gene:2504107727; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | 0.783 |
| Bcop_0205 | guaA | Bcop_0205 | Bcop_0946 | Trigger factor; COGs: COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); InterPro IPR005215:IPR008881; KEGG: bfs:BF3895 putative cell division trigger factor; PFAM: Trigger factor, ribosome-binding, bacterial; SPTR: FKBP-type peptidyl-prolyl cis-transisomerase; TIGRFAM: Trigger factor; IMG reference gene:2504105864; PFAM: Bacterial trigger factor protein (TF); TIGRFAM: trigger factor. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.537 |
| Bcop_0400 | Bcop_2008 | Bcop_0400 | Bcop_2008 | COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027:IPR004099:IPR006258; KEGG: bfs:BF0023 putative dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: Dihydrolipoyl dehydrogenase; SPTR: Putative dihydrolipoamide dehydrogenase; TIGRFAM: Dihydrolipoamide dehydrogenase; IMG reference gene:2504106063; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation d [...] | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR005946:IPR000836; KEGG: bth:BT_0748 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase; IMG reference gene:2504107727; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | 0.938 |
| Bcop_0400 | Bcop_2180 | Bcop_0400 | Bcop_2180 | COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027:IPR004099:IPR006258; KEGG: bfs:BF0023 putative dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: Dihydrolipoyl dehydrogenase; SPTR: Putative dihydrolipoamide dehydrogenase; TIGRFAM: Dihydrolipoamide dehydrogenase; IMG reference gene:2504106063; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation d [...] | COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475:IPR005476; KEGG: bfs:BF1660 putative transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: Formaldehyde transketolase; SMART: Transketolase-like, pyrimidine-binding domain; SPTR: Transketolase; IMG reference gene:2504107901; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; Belongs to the transketolase family. | 0.651 |
| Bcop_0400 | Bcop_2181 | Bcop_0400 | Bcop_2181 | COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027:IPR004099:IPR006258; KEGG: bfs:BF0023 putative dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: Dihydrolipoyl dehydrogenase; SPTR: Putative dihydrolipoamide dehydrogenase; TIGRFAM: Dihydrolipoamide dehydrogenase; IMG reference gene:2504106063; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation d [...] | Sugar-phosphate isomerase, RpiB/LacA/LacB family; COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR004785:IPR003500; KEGG: bfs:BF1659 putative ribose 5-phosphate isomerase; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Putative ribose 5-phosphate isomerase; TIGRFAM: Ribose/galactose isomerase; Ribose 5-phosphate isomerase B; IMG reference gene:2504107902; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family. | 0.447 |
| Bcop_0400 | guaA | Bcop_0400 | Bcop_0946 | COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027:IPR004099:IPR006258; KEGG: bfs:BF0023 putative dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: Dihydrolipoyl dehydrogenase; SPTR: Putative dihydrolipoamide dehydrogenase; TIGRFAM: Dihydrolipoamide dehydrogenase; IMG reference gene:2504106063; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation d [...] | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.404 |
| Bcop_1027 | Bcop_2008 | Bcop_1027 | Bcop_2008 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: bfs:BF2659 putative phosphoribosylpyrophosphate amidotransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106729. | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR005946:IPR000836; KEGG: bth:BT_0748 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase; IMG reference gene:2504107727; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | 0.902 |
| Bcop_1027 | guaA | Bcop_1027 | Bcop_0946 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: bfs:BF2659 putative phosphoribosylpyrophosphate amidotransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106729. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.789 |
| Bcop_1027 | pyrE | Bcop_1027 | Bcop_0603 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: bfs:BF2659 putative phosphoribosylpyrophosphate amidotransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106729. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.479 |
| Bcop_1081 | Bcop_2008 | Bcop_1081 | Bcop_2008 | Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845:IPR005846; KEGG: bth:BT_1548 phosphoglucomutase phosphomannomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; SPTR: Phosphoglucomutase; IMG reference gene:2504106783; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphom [...] | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR005946:IPR000836; KEGG: bth:BT_0748 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase; IMG reference gene:2504107727; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | 0.881 |
| Bcop_1081 | Bcop_2180 | Bcop_1081 | Bcop_2180 | Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845:IPR005846; KEGG: bth:BT_1548 phosphoglucomutase phosphomannomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; SPTR: Phosphoglucomutase; IMG reference gene:2504106783; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphom [...] | COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475:IPR005476; KEGG: bfs:BF1660 putative transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: Formaldehyde transketolase; SMART: Transketolase-like, pyrimidine-binding domain; SPTR: Transketolase; IMG reference gene:2504107901; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; Belongs to the transketolase family. | 0.878 |
| Bcop_1081 | Bcop_2181 | Bcop_1081 | Bcop_2181 | Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845:IPR005846; KEGG: bth:BT_1548 phosphoglucomutase phosphomannomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; SPTR: Phosphoglucomutase; IMG reference gene:2504106783; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphom [...] | Sugar-phosphate isomerase, RpiB/LacA/LacB family; COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR004785:IPR003500; KEGG: bfs:BF1659 putative ribose 5-phosphate isomerase; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Putative ribose 5-phosphate isomerase; TIGRFAM: Ribose/galactose isomerase; Ribose 5-phosphate isomerase B; IMG reference gene:2504107902; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family. | 0.860 |
| Bcop_1081 | rbsK | Bcop_1081 | Bcop_1796 | Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845:IPR005846; KEGG: bth:BT_1548 phosphoglucomutase phosphomannomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; SPTR: Phosphoglucomutase; IMG reference gene:2504106783; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphom [...] | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.859 |
| Bcop_2008 | Bcop_0205 | Bcop_2008 | Bcop_0205 | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR005946:IPR000836; KEGG: bth:BT_0748 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase; IMG reference gene:2504107727; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | Trigger factor; COGs: COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); InterPro IPR005215:IPR008881; KEGG: bfs:BF3895 putative cell division trigger factor; PFAM: Trigger factor, ribosome-binding, bacterial; SPTR: FKBP-type peptidyl-prolyl cis-transisomerase; TIGRFAM: Trigger factor; IMG reference gene:2504105864; PFAM: Bacterial trigger factor protein (TF); TIGRFAM: trigger factor. | 0.783 |
| Bcop_2008 | Bcop_0400 | Bcop_2008 | Bcop_0400 | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR005946:IPR000836; KEGG: bth:BT_0748 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase; IMG reference gene:2504107727; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027:IPR004099:IPR006258; KEGG: bfs:BF0023 putative dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: Dihydrolipoyl dehydrogenase; SPTR: Putative dihydrolipoamide dehydrogenase; TIGRFAM: Dihydrolipoamide dehydrogenase; IMG reference gene:2504106063; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation d [...] | 0.938 |
| Bcop_2008 | Bcop_1027 | Bcop_2008 | Bcop_1027 | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR005946:IPR000836; KEGG: bth:BT_0748 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase; IMG reference gene:2504107727; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: bfs:BF2659 putative phosphoribosylpyrophosphate amidotransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504106729. | 0.902 |
| Bcop_2008 | Bcop_1081 | Bcop_2008 | Bcop_1081 | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR005946:IPR000836; KEGG: bth:BT_0748 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase; IMG reference gene:2504107727; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845:IPR005846; KEGG: bth:BT_1548 phosphoglucomutase phosphomannomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; SPTR: Phosphoglucomutase; IMG reference gene:2504106783; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphom [...] | 0.881 |
| Bcop_2008 | Bcop_2180 | Bcop_2008 | Bcop_2180 | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR005946:IPR000836; KEGG: bth:BT_0748 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase; IMG reference gene:2504107727; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475:IPR005476; KEGG: bfs:BF1660 putative transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: Formaldehyde transketolase; SMART: Transketolase-like, pyrimidine-binding domain; SPTR: Transketolase; IMG reference gene:2504107901; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; Belongs to the transketolase family. | 0.924 |
| Bcop_2008 | Bcop_2181 | Bcop_2008 | Bcop_2181 | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR005946:IPR000836; KEGG: bth:BT_0748 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase; IMG reference gene:2504107727; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | Sugar-phosphate isomerase, RpiB/LacA/LacB family; COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR004785:IPR003500; KEGG: bfs:BF1659 putative ribose 5-phosphate isomerase; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Putative ribose 5-phosphate isomerase; TIGRFAM: Ribose/galactose isomerase; Ribose 5-phosphate isomerase B; IMG reference gene:2504107902; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family. | 0.897 |
| Bcop_2008 | guaA | Bcop_2008 | Bcop_0946 | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR005946:IPR000836; KEGG: bth:BT_0748 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase; IMG reference gene:2504107727; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.800 |