STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bcop_2089Fructokinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: bfs:BF3175 putative fructokinase; PFAM: Carbohydrate/purine kinase; PRIAM: Fructokinase; SPTR: Fructokinase; IMG reference gene:2504107809; PFAM: pfkB family carbohydrate kinase. (292 aa)    
Predicted Functional Partners:
Bcop_2081
Glycoside hydrolase 97; InterPro IPR019563; KEGG: bvu:BVU_0620 glycoside hydrolase family protein; PFAM: Glycoside hydrolase, family 97; SPTR: Putative lipoprotein; IMG reference gene:2504107801; PFAM: Glycoside hydrolase 97.
  
  
  0.878
Bcop_2203
COGs: COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; InterPro IPR006148:IPR003737; KEGG: bfs:BF2953 glucosamine-6-phosphate deaminase-like protein; PFAM: Glucosamine/galactosamine-6-phosphate isomerase; N-acetylglucosaminyl phosphatidylinositol deacetylase; PRIAM: Glucosamine-6-phosphate deaminase; SPTR: Putative uncharacterized protein; IMG reference gene:2504107924; PFAM: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; GlcNAc-PI de-N-acetylase; TIGRFAM: glucosamine-6-phosphate isomerase.
  
 
 0.877
Bcop_1271
Glycoside hydrolase 97; InterPro IPR019563; KEGG: bth:BT_3294 putative alpha-glucosidase; PFAM: Glycoside hydrolase, family 97; SPTR: Putative uncharacterized protein; IMG reference gene:2504106977; PFAM: Glycoside hydrolase 97.
  
  
  0.876
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
   
 0.871
Bcop_0381
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate, the first committing step of glycolysis.
   
 0.871
pfp
Diphosphate/fructose-6-phosphate1- phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
   
 0.871
fbp
Fructose-1,6-bisphosphatase class 3; COGs: COG3855 conserved hypothetical protein; HAMAP: Fructose-1,6-bisphosphatase, Bacillus type; InterPro IPR009164; KEGG: bfs:BF1884 hypothetical protein; PFAM: Fructose-1,6-bisphosphatase, Bacillus type; PRIAM: Fructose-bisphosphatase; SPTR: Putative uncharacterized protein; IMG reference gene:2504108037; PFAM: Firmicute fructose-1,6-bisphosphatase.
     
 0.868
pgi
COGs: COG0166 Glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: bfs:BF3604 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); PRIAM: Glucose-6-phosphate isomerase; SPTR: Putative glucose-6-phosphate isomerase; IMG reference gene:2504108184; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
  
 
 0.868
Bcop_2176
Mannose-6-phosphate isomerase, class I; COGs: COG1482 Phosphomannose isomerase; InterPro IPR001250; KEGG: bth:BT_0373 mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type I; PRIAM: Mannose-6-phosphate isomerase; SPTR: Putative uncharacterized protein; TIGRFAM: Mannose-6-phosphate isomerase, type I; IMG reference gene:2504107897; PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I.
    
 0.861
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
   
 
 0.859
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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