| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bcop_0381 | Bcop_2089 | Bcop_0381 | Bcop_2089 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate, the first committing step of glycolysis. | Fructokinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: bfs:BF3175 putative fructokinase; PFAM: Carbohydrate/purine kinase; PRIAM: Fructokinase; SPTR: Fructokinase; IMG reference gene:2504107809; PFAM: pfkB family carbohydrate kinase. | 0.871 |
| Bcop_0381 | Bcop_2176 | Bcop_0381 | Bcop_2176 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate, the first committing step of glycolysis. | Mannose-6-phosphate isomerase, class I; COGs: COG1482 Phosphomannose isomerase; InterPro IPR001250; KEGG: bth:BT_0373 mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type I; PRIAM: Mannose-6-phosphate isomerase; SPTR: Putative uncharacterized protein; TIGRFAM: Mannose-6-phosphate isomerase, type I; IMG reference gene:2504107897; PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I. | 0.864 |
| Bcop_0381 | fbp | Bcop_0381 | Bcop_2312 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate, the first committing step of glycolysis. | Fructose-1,6-bisphosphatase class 3; COGs: COG3855 conserved hypothetical protein; HAMAP: Fructose-1,6-bisphosphatase, Bacillus type; InterPro IPR009164; KEGG: bfs:BF1884 hypothetical protein; PFAM: Fructose-1,6-bisphosphatase, Bacillus type; PRIAM: Fructose-bisphosphatase; SPTR: Putative uncharacterized protein; IMG reference gene:2504108037; PFAM: Firmicute fructose-1,6-bisphosphatase. | 0.866 |
| Bcop_0381 | pfkA | Bcop_0381 | Bcop_0079 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate, the first committing step of glycolysis. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.940 |
| Bcop_0381 | pfp | Bcop_0381 | Bcop_2196 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate, the first committing step of glycolysis. | Diphosphate/fructose-6-phosphate1- phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.857 |
| Bcop_0381 | pgi | Bcop_0381 | Bcop_2452 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate, the first committing step of glycolysis. | COGs: COG0166 Glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: bfs:BF3604 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); PRIAM: Glucose-6-phosphate isomerase; SPTR: Putative glucose-6-phosphate isomerase; IMG reference gene:2504108184; PFAM: Phosphoglucose isomerase; Belongs to the GPI family. | 0.935 |
| Bcop_1271 | Bcop_2081 | Bcop_1271 | Bcop_2081 | Glycoside hydrolase 97; InterPro IPR019563; KEGG: bth:BT_3294 putative alpha-glucosidase; PFAM: Glycoside hydrolase, family 97; SPTR: Putative uncharacterized protein; IMG reference gene:2504106977; PFAM: Glycoside hydrolase 97. | Glycoside hydrolase 97; InterPro IPR019563; KEGG: bvu:BVU_0620 glycoside hydrolase family protein; PFAM: Glycoside hydrolase, family 97; SPTR: Putative lipoprotein; IMG reference gene:2504107801; PFAM: Glycoside hydrolase 97. | 0.896 |
| Bcop_1271 | Bcop_2089 | Bcop_1271 | Bcop_2089 | Glycoside hydrolase 97; InterPro IPR019563; KEGG: bth:BT_3294 putative alpha-glucosidase; PFAM: Glycoside hydrolase, family 97; SPTR: Putative uncharacterized protein; IMG reference gene:2504106977; PFAM: Glycoside hydrolase 97. | Fructokinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: bfs:BF3175 putative fructokinase; PFAM: Carbohydrate/purine kinase; PRIAM: Fructokinase; SPTR: Fructokinase; IMG reference gene:2504107809; PFAM: pfkB family carbohydrate kinase. | 0.876 |
| Bcop_2081 | Bcop_1271 | Bcop_2081 | Bcop_1271 | Glycoside hydrolase 97; InterPro IPR019563; KEGG: bvu:BVU_0620 glycoside hydrolase family protein; PFAM: Glycoside hydrolase, family 97; SPTR: Putative lipoprotein; IMG reference gene:2504107801; PFAM: Glycoside hydrolase 97. | Glycoside hydrolase 97; InterPro IPR019563; KEGG: bth:BT_3294 putative alpha-glucosidase; PFAM: Glycoside hydrolase, family 97; SPTR: Putative uncharacterized protein; IMG reference gene:2504106977; PFAM: Glycoside hydrolase 97. | 0.896 |
| Bcop_2081 | Bcop_2089 | Bcop_2081 | Bcop_2089 | Glycoside hydrolase 97; InterPro IPR019563; KEGG: bvu:BVU_0620 glycoside hydrolase family protein; PFAM: Glycoside hydrolase, family 97; SPTR: Putative lipoprotein; IMG reference gene:2504107801; PFAM: Glycoside hydrolase 97. | Fructokinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: bfs:BF3175 putative fructokinase; PFAM: Carbohydrate/purine kinase; PRIAM: Fructokinase; SPTR: Fructokinase; IMG reference gene:2504107809; PFAM: pfkB family carbohydrate kinase. | 0.878 |
| Bcop_2089 | Bcop_0381 | Bcop_2089 | Bcop_0381 | Fructokinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: bfs:BF3175 putative fructokinase; PFAM: Carbohydrate/purine kinase; PRIAM: Fructokinase; SPTR: Fructokinase; IMG reference gene:2504107809; PFAM: pfkB family carbohydrate kinase. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate, the first committing step of glycolysis. | 0.871 |
| Bcop_2089 | Bcop_1271 | Bcop_2089 | Bcop_1271 | Fructokinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: bfs:BF3175 putative fructokinase; PFAM: Carbohydrate/purine kinase; PRIAM: Fructokinase; SPTR: Fructokinase; IMG reference gene:2504107809; PFAM: pfkB family carbohydrate kinase. | Glycoside hydrolase 97; InterPro IPR019563; KEGG: bth:BT_3294 putative alpha-glucosidase; PFAM: Glycoside hydrolase, family 97; SPTR: Putative uncharacterized protein; IMG reference gene:2504106977; PFAM: Glycoside hydrolase 97. | 0.876 |
| Bcop_2089 | Bcop_2081 | Bcop_2089 | Bcop_2081 | Fructokinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: bfs:BF3175 putative fructokinase; PFAM: Carbohydrate/purine kinase; PRIAM: Fructokinase; SPTR: Fructokinase; IMG reference gene:2504107809; PFAM: pfkB family carbohydrate kinase. | Glycoside hydrolase 97; InterPro IPR019563; KEGG: bvu:BVU_0620 glycoside hydrolase family protein; PFAM: Glycoside hydrolase, family 97; SPTR: Putative lipoprotein; IMG reference gene:2504107801; PFAM: Glycoside hydrolase 97. | 0.878 |
| Bcop_2089 | Bcop_2176 | Bcop_2089 | Bcop_2176 | Fructokinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: bfs:BF3175 putative fructokinase; PFAM: Carbohydrate/purine kinase; PRIAM: Fructokinase; SPTR: Fructokinase; IMG reference gene:2504107809; PFAM: pfkB family carbohydrate kinase. | Mannose-6-phosphate isomerase, class I; COGs: COG1482 Phosphomannose isomerase; InterPro IPR001250; KEGG: bth:BT_0373 mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type I; PRIAM: Mannose-6-phosphate isomerase; SPTR: Putative uncharacterized protein; TIGRFAM: Mannose-6-phosphate isomerase, type I; IMG reference gene:2504107897; PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I. | 0.861 |
| Bcop_2089 | Bcop_2203 | Bcop_2089 | Bcop_2203 | Fructokinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: bfs:BF3175 putative fructokinase; PFAM: Carbohydrate/purine kinase; PRIAM: Fructokinase; SPTR: Fructokinase; IMG reference gene:2504107809; PFAM: pfkB family carbohydrate kinase. | COGs: COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; InterPro IPR006148:IPR003737; KEGG: bfs:BF2953 glucosamine-6-phosphate deaminase-like protein; PFAM: Glucosamine/galactosamine-6-phosphate isomerase; N-acetylglucosaminyl phosphatidylinositol deacetylase; PRIAM: Glucosamine-6-phosphate deaminase; SPTR: Putative uncharacterized protein; IMG reference gene:2504107924; PFAM: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; GlcNAc-PI de-N-acetylase; TIGRFAM: glucosamine-6-phosphate isomerase. | 0.877 |
| Bcop_2089 | fbp | Bcop_2089 | Bcop_2312 | Fructokinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: bfs:BF3175 putative fructokinase; PFAM: Carbohydrate/purine kinase; PRIAM: Fructokinase; SPTR: Fructokinase; IMG reference gene:2504107809; PFAM: pfkB family carbohydrate kinase. | Fructose-1,6-bisphosphatase class 3; COGs: COG3855 conserved hypothetical protein; HAMAP: Fructose-1,6-bisphosphatase, Bacillus type; InterPro IPR009164; KEGG: bfs:BF1884 hypothetical protein; PFAM: Fructose-1,6-bisphosphatase, Bacillus type; PRIAM: Fructose-bisphosphatase; SPTR: Putative uncharacterized protein; IMG reference gene:2504108037; PFAM: Firmicute fructose-1,6-bisphosphatase. | 0.868 |
| Bcop_2089 | nagB | Bcop_2089 | Bcop_0745 | Fructokinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: bfs:BF3175 putative fructokinase; PFAM: Carbohydrate/purine kinase; PRIAM: Fructokinase; SPTR: Fructokinase; IMG reference gene:2504107809; PFAM: pfkB family carbohydrate kinase. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily. | 0.859 |
| Bcop_2089 | pfkA | Bcop_2089 | Bcop_0079 | Fructokinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: bfs:BF3175 putative fructokinase; PFAM: Carbohydrate/purine kinase; PRIAM: Fructokinase; SPTR: Fructokinase; IMG reference gene:2504107809; PFAM: pfkB family carbohydrate kinase. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.871 |
| Bcop_2089 | pfp | Bcop_2089 | Bcop_2196 | Fructokinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: bfs:BF3175 putative fructokinase; PFAM: Carbohydrate/purine kinase; PRIAM: Fructokinase; SPTR: Fructokinase; IMG reference gene:2504107809; PFAM: pfkB family carbohydrate kinase. | Diphosphate/fructose-6-phosphate1- phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.871 |
| Bcop_2089 | pgi | Bcop_2089 | Bcop_2452 | Fructokinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: bfs:BF3175 putative fructokinase; PFAM: Carbohydrate/purine kinase; PRIAM: Fructokinase; SPTR: Fructokinase; IMG reference gene:2504107809; PFAM: pfkB family carbohydrate kinase. | COGs: COG0166 Glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: bfs:BF3604 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); PRIAM: Glucose-6-phosphate isomerase; SPTR: Putative glucose-6-phosphate isomerase; IMG reference gene:2504108184; PFAM: Phosphoglucose isomerase; Belongs to the GPI family. | 0.868 |