| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bcop_0122 | Bcop_0448 | Bcop_0122 | Bcop_0448 | Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: bth:BT_3948 putative exopolyphosphatase-like protein; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Exopolyphosphatase-related proteins; IMG reference gene:2504105778; PFAM: DHH family; DHHA1 domain. | COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953:IPR004112:IPR011280; KEGG: bfs:BF4340 succinate dehydrogenase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; PRIAM: Succinate dehydrogenase; SPTR: Fumarate reductase flavoprotein subunit; TIGRFAM: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, low-GC Gram-positive bacteria; IMG reference gene:2504106112; PFAM: domain; FAD binding domain; TIGRFAM: succina [...] | 0.402 |
| Bcop_0122 | Bcop_2183 | Bcop_0122 | Bcop_2183 | Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: bth:BT_3948 putative exopolyphosphatase-like protein; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Exopolyphosphatase-related proteins; IMG reference gene:2504105778; PFAM: DHH family; DHHA1 domain. | InterPro IPR001450; KEGG: bfs:BF1657 putative ferredoxin; PFAM: 4Fe-4S binding domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504107904; PFAM: 4Fe-4S binding domain. | 0.402 |
| Bcop_0122 | cysC | Bcop_0122 | Bcop_2165 | Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: bth:BT_3948 putative exopolyphosphatase-like protein; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Exopolyphosphatase-related proteins; IMG reference gene:2504105778; PFAM: DHH family; DHHA1 domain. | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.857 |
| Bcop_0122 | cysD | Bcop_0122 | Bcop_2164 | Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: bth:BT_3948 putative exopolyphosphatase-like protein; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Exopolyphosphatase-related proteins; IMG reference gene:2504105778; PFAM: DHH family; DHHA1 domain. | Sulfate adenylyltransferase subunit 2; COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; HAMAP: Sulphate adenylyltransferase, small subunit; InterPro IPR011784:IPR002500; KEGG: bvu:BVU_0417 sulfate adenylyltransferase subunit 2; PFAM: Phosphoadenosine phosphosulphate reductase; PRIAM: Sulfate adenylyltransferase; SPTR: Sulfate adenylyltransferase subunit 2; TIGRFAM: Sulphate adenylyltransferase, small subunit; IMG reference gene:2504107885; PFAM: Phosphoadenosine phosphosulfate reductase family; TIGRFAM: sulfate adenylyltransferase, s [...] | 0.858 |
| Bcop_0122 | cysN | Bcop_0122 | Bcop_2163 | Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: bth:BT_3948 putative exopolyphosphatase-like protein; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Exopolyphosphatase-related proteins; IMG reference gene:2504105778; PFAM: DHH family; DHHA1 domain. | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.864 |
| Bcop_0122 | cysQ | Bcop_0122 | Bcop_2167 | Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: bth:BT_3948 putative exopolyphosphatase-like protein; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Exopolyphosphatase-related proteins; IMG reference gene:2504105778; PFAM: DHH family; DHHA1 domain. | 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.859 |
| Bcop_0319 | Bcop_0625 | Bcop_0319 | Bcop_0625 | COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005856:IPR005859; KEGG: bfs:BF4362 putative cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; IMG reference gene:2504105980; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | 0.965 |
| Bcop_0319 | cysC | Bcop_0319 | Bcop_2165 | COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005856:IPR005859; KEGG: bfs:BF4362 putative cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; IMG reference gene:2504105980; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.480 |
| Bcop_0319 | cysD | Bcop_0319 | Bcop_2164 | COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005856:IPR005859; KEGG: bfs:BF4362 putative cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; IMG reference gene:2504105980; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Sulfate adenylyltransferase subunit 2; COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; HAMAP: Sulphate adenylyltransferase, small subunit; InterPro IPR011784:IPR002500; KEGG: bvu:BVU_0417 sulfate adenylyltransferase subunit 2; PFAM: Phosphoadenosine phosphosulphate reductase; PRIAM: Sulfate adenylyltransferase; SPTR: Sulfate adenylyltransferase subunit 2; TIGRFAM: Sulphate adenylyltransferase, small subunit; IMG reference gene:2504107885; PFAM: Phosphoadenosine phosphosulfate reductase family; TIGRFAM: sulfate adenylyltransferase, s [...] | 0.582 |
| Bcop_0319 | cysN | Bcop_0319 | Bcop_2163 | COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005856:IPR005859; KEGG: bfs:BF4362 putative cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; IMG reference gene:2504105980; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.939 |
| Bcop_0448 | Bcop_0122 | Bcop_0448 | Bcop_0122 | COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953:IPR004112:IPR011280; KEGG: bfs:BF4340 succinate dehydrogenase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; PRIAM: Succinate dehydrogenase; SPTR: Fumarate reductase flavoprotein subunit; TIGRFAM: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, low-GC Gram-positive bacteria; IMG reference gene:2504106112; PFAM: domain; FAD binding domain; TIGRFAM: succina [...] | Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: bth:BT_3948 putative exopolyphosphatase-like protein; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Exopolyphosphatase-related proteins; IMG reference gene:2504105778; PFAM: DHH family; DHHA1 domain. | 0.402 |
| Bcop_0448 | Bcop_0625 | Bcop_0448 | Bcop_0625 | COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953:IPR004112:IPR011280; KEGG: bfs:BF4340 succinate dehydrogenase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; PRIAM: Succinate dehydrogenase; SPTR: Fumarate reductase flavoprotein subunit; TIGRFAM: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, low-GC Gram-positive bacteria; IMG reference gene:2504106112; PFAM: domain; FAD binding domain; TIGRFAM: succina [...] | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | 0.822 |
| Bcop_0448 | Bcop_2183 | Bcop_0448 | Bcop_2183 | COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953:IPR004112:IPR011280; KEGG: bfs:BF4340 succinate dehydrogenase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; PRIAM: Succinate dehydrogenase; SPTR: Fumarate reductase flavoprotein subunit; TIGRFAM: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, low-GC Gram-positive bacteria; IMG reference gene:2504106112; PFAM: domain; FAD binding domain; TIGRFAM: succina [...] | InterPro IPR001450; KEGG: bfs:BF1657 putative ferredoxin; PFAM: 4Fe-4S binding domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504107904; PFAM: 4Fe-4S binding domain. | 0.605 |
| Bcop_0448 | cysD | Bcop_0448 | Bcop_2164 | COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953:IPR004112:IPR011280; KEGG: bfs:BF4340 succinate dehydrogenase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; PRIAM: Succinate dehydrogenase; SPTR: Fumarate reductase flavoprotein subunit; TIGRFAM: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, low-GC Gram-positive bacteria; IMG reference gene:2504106112; PFAM: domain; FAD binding domain; TIGRFAM: succina [...] | Sulfate adenylyltransferase subunit 2; COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; HAMAP: Sulphate adenylyltransferase, small subunit; InterPro IPR011784:IPR002500; KEGG: bvu:BVU_0417 sulfate adenylyltransferase subunit 2; PFAM: Phosphoadenosine phosphosulphate reductase; PRIAM: Sulfate adenylyltransferase; SPTR: Sulfate adenylyltransferase subunit 2; TIGRFAM: Sulphate adenylyltransferase, small subunit; IMG reference gene:2504107885; PFAM: Phosphoadenosine phosphosulfate reductase family; TIGRFAM: sulfate adenylyltransferase, s [...] | 0.510 |
| Bcop_0448 | cysN | Bcop_0448 | Bcop_2163 | COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953:IPR004112:IPR011280; KEGG: bfs:BF4340 succinate dehydrogenase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; PRIAM: Succinate dehydrogenase; SPTR: Fumarate reductase flavoprotein subunit; TIGRFAM: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, low-GC Gram-positive bacteria; IMG reference gene:2504106112; PFAM: domain; FAD binding domain; TIGRFAM: succina [...] | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.856 |
| Bcop_0448 | cysQ | Bcop_0448 | Bcop_2167 | COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953:IPR004112:IPR011280; KEGG: bfs:BF4340 succinate dehydrogenase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; PRIAM: Succinate dehydrogenase; SPTR: Fumarate reductase flavoprotein subunit; TIGRFAM: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, low-GC Gram-positive bacteria; IMG reference gene:2504106112; PFAM: domain; FAD binding domain; TIGRFAM: succina [...] | 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.431 |
| Bcop_0625 | Bcop_0319 | Bcop_0625 | Bcop_0319 | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005856:IPR005859; KEGG: bfs:BF4362 putative cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; IMG reference gene:2504105980; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.965 |
| Bcop_0625 | Bcop_0448 | Bcop_0625 | Bcop_0448 | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953:IPR004112:IPR011280; KEGG: bfs:BF4340 succinate dehydrogenase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; PRIAM: Succinate dehydrogenase; SPTR: Fumarate reductase flavoprotein subunit; TIGRFAM: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, low-GC Gram-positive bacteria; IMG reference gene:2504106112; PFAM: domain; FAD binding domain; TIGRFAM: succina [...] | 0.822 |
| Bcop_0625 | Bcop_2166 | Bcop_0625 | Bcop_2166 | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | TrkA-C domain protein; COGs: COG0471 Di- and tricarboxylate transporter; InterPro IPR004680:IPR006037; KEGG: bth:BT_0412 putative Na+/sulfate symporter; PFAM: Regulator of K+ conductance, C-terminal; Divalent ion symporter; SPTR: Putative uncharacterized protein; IMG reference gene:2504107887; PFAM: Citrate transporter; TrkA-C domain. | 0.658 |
| Bcop_0625 | Bcop_2183 | Bcop_0625 | Bcop_2183 | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | InterPro IPR001450; KEGG: bfs:BF1657 putative ferredoxin; PFAM: 4Fe-4S binding domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504107904; PFAM: 4Fe-4S binding domain. | 0.882 |