STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bcop_2166TrkA-C domain protein; COGs: COG0471 Di- and tricarboxylate transporter; InterPro IPR004680:IPR006037; KEGG: bth:BT_0412 putative Na+/sulfate symporter; PFAM: Regulator of K+ conductance, C-terminal; Divalent ion symporter; SPTR: Putative uncharacterized protein; IMG reference gene:2504107887; PFAM: Citrate transporter; TrkA-C domain. (515 aa)    
Predicted Functional Partners:
cysQ
3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.
 
  
 0.896
cysC
Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate.
 
  
 0.894
Bcop_2162
KEGG: bth:BT_0416 hypothetical protein; SPTR: Possible sulfotransferase; IMG reference gene:2504107883; PFAM: Sulfotransferase domain.
 
    0.888
cysN
Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.864
cysD
Sulfate adenylyltransferase subunit 2; COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; HAMAP: Sulphate adenylyltransferase, small subunit; InterPro IPR011784:IPR002500; KEGG: bvu:BVU_0417 sulfate adenylyltransferase subunit 2; PFAM: Phosphoadenosine phosphosulphate reductase; PRIAM: Sulfate adenylyltransferase; SPTR: Sulfate adenylyltransferase subunit 2; TIGRFAM: Sulphate adenylyltransferase, small subunit; IMG reference gene:2504107885; PFAM: Phosphoadenosine phosphosulfate reductase family; TIGRFAM: sulfate adenylyltransferase, s [...]
  
  
 0.786
Bcop_2161
KEGG: bfs:BF1679 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504107882.
 
     0.745
Bcop_0008
Malic protein NAD-binding; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: bth:BT_1969 malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SMART: Malic enzyme, NAD-binding; SPTR: NADP-dependent malic enzyme; IMG reference gene:2504105663; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
  
  
 0.614
Bcop_2386
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: bth:BT_1747 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain; SPTR: Pyru [...]
  
  
 0.600
Bcop_0126
Cl- channel voltage-gated family protein; COGs: COG0038 Chloride channel protein EriC; InterPro IPR001807:IPR000644; KEGG: bfs:BF3674 putative transport related, membrane protein; PFAM: Chloride channel, voltage gated; Cystathionine beta-synthase, core; SPTR: Putative chloride channel protein; IMG reference gene:2504105782; PFAM: CBS domain; Voltage gated chloride channel.
  
  
 0.583
Bcop_1054
Sodium/hydrogen exchanger; COGs: COG4651 Kef-type K+ transport system predicted NAD-binding component; InterPro IPR006153:IPR006037; KEGG: pdi:BDI_0523 putative Na+/H+ antiporter; PFAM: Cation/H+ exchanger; Regulator of K+ conductance, C-terminal; SPTR: TrkA-C domain protein; IMG reference gene:2504106756; PFAM: TrkA-C domain; Sodium/hydrogen exchanger family.
     
 0.580
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.