| node1 | node2 | node1 annotation | node2 annotation | score |
| Bcop_0817 | Bcop_1233 | NAD+ synthetase; COGs: COG0171 NAD synthase; InterPro IPR003010:IPR022310:IPR003694; KEGG: bth:BT_0205 NAD synthetase; PFAM: NAD/GMP synthase; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PRIAM: NAD(+) synthase (glutamine-hydrolyzing); SPTR: Putative uncharacterized protein; TIGRFAM: NAD synthase; IMG reference gene:2504106506; PFAM: NAD synthase; TIGRFAM: NAD+ synthetase. | Competence/damage-inducible protein CinA; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008135:IPR020817:IPR008136:IPR001453; KEGG: bfs:BF2511 putative competence-damage inducible; PFAM: CinA, C-terminal; Molybdopterin binding; SMART: Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; Molybdenum cofactor synthesis; CinA, C-terminal; IMG reference gene:2504106937; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-ter [...] | 0.934 |
| Bcop_0817 | Bcop_2174 | NAD+ synthetase; COGs: COG0171 NAD synthase; InterPro IPR003010:IPR022310:IPR003694; KEGG: bth:BT_0205 NAD synthetase; PFAM: NAD/GMP synthase; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PRIAM: NAD(+) synthase (glutamine-hydrolyzing); SPTR: Putative uncharacterized protein; TIGRFAM: NAD synthase; IMG reference gene:2504106506; PFAM: NAD synthase; TIGRFAM: NAD+ synthetase. | Helix-turn-helix domain protein; InterPro IPR001387; KEGG: bvu:BVU_3759 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504107895; PFAM: Helix-turn-helix. | 0.573 |
| Bcop_0817 | Bcop_2386 | NAD+ synthetase; COGs: COG0171 NAD synthase; InterPro IPR003010:IPR022310:IPR003694; KEGG: bth:BT_0205 NAD synthetase; PFAM: NAD/GMP synthase; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PRIAM: NAD(+) synthase (glutamine-hydrolyzing); SPTR: Putative uncharacterized protein; TIGRFAM: NAD synthase; IMG reference gene:2504106506; PFAM: NAD synthase; TIGRFAM: NAD+ synthetase. | COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: bth:BT_1747 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain; SPTR: Pyru [...] | 0.874 |
| Bcop_1233 | Bcop_0817 | Competence/damage-inducible protein CinA; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008135:IPR020817:IPR008136:IPR001453; KEGG: bfs:BF2511 putative competence-damage inducible; PFAM: CinA, C-terminal; Molybdopterin binding; SMART: Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; Molybdenum cofactor synthesis; CinA, C-terminal; IMG reference gene:2504106937; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-ter [...] | NAD+ synthetase; COGs: COG0171 NAD synthase; InterPro IPR003010:IPR022310:IPR003694; KEGG: bth:BT_0205 NAD synthetase; PFAM: NAD/GMP synthase; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PRIAM: NAD(+) synthase (glutamine-hydrolyzing); SPTR: Putative uncharacterized protein; TIGRFAM: NAD synthase; IMG reference gene:2504106506; PFAM: NAD synthase; TIGRFAM: NAD+ synthetase. | 0.934 |
| Bcop_1233 | Bcop_2174 | Competence/damage-inducible protein CinA; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008135:IPR020817:IPR008136:IPR001453; KEGG: bfs:BF2511 putative competence-damage inducible; PFAM: CinA, C-terminal; Molybdopterin binding; SMART: Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; Molybdenum cofactor synthesis; CinA, C-terminal; IMG reference gene:2504106937; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-ter [...] | Helix-turn-helix domain protein; InterPro IPR001387; KEGG: bvu:BVU_3759 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504107895; PFAM: Helix-turn-helix. | 0.691 |
| Bcop_1842 | Bcop_1843 | HipA domain protein; COGs: COG3550 conserved hypothetical protein; InterPro IPR012894:IPR012893; KEGG: pgi:PG0859 hypothetical protein; PFAM: HipA-like, C-terminal; HipA-like, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504107558; PFAM: HipA-like C-terminal domain; HipA-like N-terminal domain. | HipA N-terminal domain protein; InterPro IPR017508; KEGG: pgi:PG0858 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: HipA, N-terminal; IMG reference gene:2504107559; TIGRFAM: HipA N-terminal domain. | 0.963 |
| Bcop_1842 | Bcop_1932 | HipA domain protein; COGs: COG3550 conserved hypothetical protein; InterPro IPR012894:IPR012893; KEGG: pgi:PG0859 hypothetical protein; PFAM: HipA-like, C-terminal; HipA-like, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504107558; PFAM: HipA-like C-terminal domain; HipA-like N-terminal domain. | HipA domain protein; COGs: COG3550 conserved hypothetical protein; InterPro IPR012894:IPR012893; KEGG: zpr:ZPR_3974 protein containing HipA-like C-terminal domain; PFAM: HipA-like, C-terminal; HipA-like, N-terminal; SPTR: Protein containing hipA-like C-terminal domain; IMG reference gene:2504107648; PFAM: HipA-like C-terminal domain; HipA-like N-terminal domain. | 0.513 |
| Bcop_1842 | Bcop_2174 | HipA domain protein; COGs: COG3550 conserved hypothetical protein; InterPro IPR012894:IPR012893; KEGG: pgi:PG0859 hypothetical protein; PFAM: HipA-like, C-terminal; HipA-like, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504107558; PFAM: HipA-like C-terminal domain; HipA-like N-terminal domain. | Helix-turn-helix domain protein; InterPro IPR001387; KEGG: bvu:BVU_3759 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504107895; PFAM: Helix-turn-helix. | 0.471 |
| Bcop_1843 | Bcop_1842 | HipA N-terminal domain protein; InterPro IPR017508; KEGG: pgi:PG0858 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: HipA, N-terminal; IMG reference gene:2504107559; TIGRFAM: HipA N-terminal domain. | HipA domain protein; COGs: COG3550 conserved hypothetical protein; InterPro IPR012894:IPR012893; KEGG: pgi:PG0859 hypothetical protein; PFAM: HipA-like, C-terminal; HipA-like, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504107558; PFAM: HipA-like C-terminal domain; HipA-like N-terminal domain. | 0.963 |
| Bcop_1843 | Bcop_2173 | HipA N-terminal domain protein; InterPro IPR017508; KEGG: pgi:PG0858 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: HipA, N-terminal; IMG reference gene:2504107559; TIGRFAM: HipA N-terminal domain. | HipA domain protein; COGs: COG3550 conserved hypothetical protein; InterPro IPR012894:IPR012893; KEGG: pru:PRU_0523 HipA domain-containing protein; PFAM: HipA-like, C-terminal; HipA-like, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504107894; PFAM: HipA-like N-terminal domain; HipA-like C-terminal domain. | 0.548 |
| Bcop_1843 | Bcop_2174 | HipA N-terminal domain protein; InterPro IPR017508; KEGG: pgi:PG0858 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: HipA, N-terminal; IMG reference gene:2504107559; TIGRFAM: HipA N-terminal domain. | Helix-turn-helix domain protein; InterPro IPR001387; KEGG: bvu:BVU_3759 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504107895; PFAM: Helix-turn-helix. | 0.471 |
| Bcop_1932 | Bcop_1842 | HipA domain protein; COGs: COG3550 conserved hypothetical protein; InterPro IPR012894:IPR012893; KEGG: zpr:ZPR_3974 protein containing HipA-like C-terminal domain; PFAM: HipA-like, C-terminal; HipA-like, N-terminal; SPTR: Protein containing hipA-like C-terminal domain; IMG reference gene:2504107648; PFAM: HipA-like C-terminal domain; HipA-like N-terminal domain. | HipA domain protein; COGs: COG3550 conserved hypothetical protein; InterPro IPR012894:IPR012893; KEGG: pgi:PG0859 hypothetical protein; PFAM: HipA-like, C-terminal; HipA-like, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504107558; PFAM: HipA-like C-terminal domain; HipA-like N-terminal domain. | 0.513 |
| Bcop_1932 | Bcop_2174 | HipA domain protein; COGs: COG3550 conserved hypothetical protein; InterPro IPR012894:IPR012893; KEGG: zpr:ZPR_3974 protein containing HipA-like C-terminal domain; PFAM: HipA-like, C-terminal; HipA-like, N-terminal; SPTR: Protein containing hipA-like C-terminal domain; IMG reference gene:2504107648; PFAM: HipA-like C-terminal domain; HipA-like N-terminal domain. | Helix-turn-helix domain protein; InterPro IPR001387; KEGG: bvu:BVU_3759 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504107895; PFAM: Helix-turn-helix. | 0.490 |
| Bcop_2173 | Bcop_1843 | HipA domain protein; COGs: COG3550 conserved hypothetical protein; InterPro IPR012894:IPR012893; KEGG: pru:PRU_0523 HipA domain-containing protein; PFAM: HipA-like, C-terminal; HipA-like, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504107894; PFAM: HipA-like N-terminal domain; HipA-like C-terminal domain. | HipA N-terminal domain protein; InterPro IPR017508; KEGG: pgi:PG0858 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: HipA, N-terminal; IMG reference gene:2504107559; TIGRFAM: HipA N-terminal domain. | 0.548 |
| Bcop_2173 | Bcop_2174 | HipA domain protein; COGs: COG3550 conserved hypothetical protein; InterPro IPR012894:IPR012893; KEGG: pru:PRU_0523 HipA domain-containing protein; PFAM: HipA-like, C-terminal; HipA-like, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504107894; PFAM: HipA-like N-terminal domain; HipA-like C-terminal domain. | Helix-turn-helix domain protein; InterPro IPR001387; KEGG: bvu:BVU_3759 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504107895; PFAM: Helix-turn-helix. | 0.914 |
| Bcop_2174 | Bcop_0817 | Helix-turn-helix domain protein; InterPro IPR001387; KEGG: bvu:BVU_3759 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504107895; PFAM: Helix-turn-helix. | NAD+ synthetase; COGs: COG0171 NAD synthase; InterPro IPR003010:IPR022310:IPR003694; KEGG: bth:BT_0205 NAD synthetase; PFAM: NAD/GMP synthase; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PRIAM: NAD(+) synthase (glutamine-hydrolyzing); SPTR: Putative uncharacterized protein; TIGRFAM: NAD synthase; IMG reference gene:2504106506; PFAM: NAD synthase; TIGRFAM: NAD+ synthetase. | 0.573 |
| Bcop_2174 | Bcop_1233 | Helix-turn-helix domain protein; InterPro IPR001387; KEGG: bvu:BVU_3759 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504107895; PFAM: Helix-turn-helix. | Competence/damage-inducible protein CinA; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008135:IPR020817:IPR008136:IPR001453; KEGG: bfs:BF2511 putative competence-damage inducible; PFAM: CinA, C-terminal; Molybdopterin binding; SMART: Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; Molybdenum cofactor synthesis; CinA, C-terminal; IMG reference gene:2504106937; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-ter [...] | 0.691 |
| Bcop_2174 | Bcop_1842 | Helix-turn-helix domain protein; InterPro IPR001387; KEGG: bvu:BVU_3759 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504107895; PFAM: Helix-turn-helix. | HipA domain protein; COGs: COG3550 conserved hypothetical protein; InterPro IPR012894:IPR012893; KEGG: pgi:PG0859 hypothetical protein; PFAM: HipA-like, C-terminal; HipA-like, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504107558; PFAM: HipA-like C-terminal domain; HipA-like N-terminal domain. | 0.471 |
| Bcop_2174 | Bcop_1843 | Helix-turn-helix domain protein; InterPro IPR001387; KEGG: bvu:BVU_3759 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504107895; PFAM: Helix-turn-helix. | HipA N-terminal domain protein; InterPro IPR017508; KEGG: pgi:PG0858 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: HipA, N-terminal; IMG reference gene:2504107559; TIGRFAM: HipA N-terminal domain. | 0.471 |
| Bcop_2174 | Bcop_1932 | Helix-turn-helix domain protein; InterPro IPR001387; KEGG: bvu:BVU_3759 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504107895; PFAM: Helix-turn-helix. | HipA domain protein; COGs: COG3550 conserved hypothetical protein; InterPro IPR012894:IPR012893; KEGG: zpr:ZPR_3974 protein containing HipA-like C-terminal domain; PFAM: HipA-like, C-terminal; HipA-like, N-terminal; SPTR: Protein containing hipA-like C-terminal domain; IMG reference gene:2504107648; PFAM: HipA-like C-terminal domain; HipA-like N-terminal domain. | 0.490 |