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query proteins and first shell of interactors
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second shell of interactors
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pfpDiphosphate/fructose-6-phosphate1- phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (547 aa)    
Predicted Functional Partners:
Bcop_0929
Fructose-1,6-bisphosphate aldolase, class II; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771:IPR011289; KEGG: bfs:BF3138 fructose-bisphosphate aldolase; PFAM: Ketose-bisphosphate aldolase, class-II; PRIAM: Fructose-bisphosphate aldolase; SPTR: Fructose-bisphosphate aldolase; TIGRFAM: Fructose-1,6-bisphosphate aldolase, class 2; Ketose-bisphosphate aldolase, class-II; IMG reference gene:2504106625; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochon [...]
  
 
 0.941
pgi
COGs: COG0166 Glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: bfs:BF3604 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); PRIAM: Glucose-6-phosphate isomerase; SPTR: Putative glucose-6-phosphate isomerase; IMG reference gene:2504108184; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
  
 0.935
Bcop_0683
Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG1830 DhnA-type fructose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: bfs:BF3090 fructose-bisphosphate aldolase; PFAM: Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; SPTR: Putative fructose-bisphosphate aldolase class I; IMG reference gene:2504106363; PFAM: DeoC/LacD family aldolase.
    
 0.930
Bcop_2180
COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475:IPR005476; KEGG: bfs:BF1660 putative transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: Formaldehyde transketolase; SMART: Transketolase-like, pyrimidine-binding domain; SPTR: Transketolase; IMG reference gene:2504107901; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; Belongs to the transketolase family.
  
 0.879
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
   
 0.874
Bcop_2089
Fructokinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: bfs:BF3175 putative fructokinase; PFAM: Carbohydrate/purine kinase; PRIAM: Fructokinase; SPTR: Fructokinase; IMG reference gene:2504107809; PFAM: pfkB family carbohydrate kinase.
   
 0.871
fbp
Fructose-1,6-bisphosphatase class 3; COGs: COG3855 conserved hypothetical protein; HAMAP: Fructose-1,6-bisphosphatase, Bacillus type; InterPro IPR009164; KEGG: bfs:BF1884 hypothetical protein; PFAM: Fructose-1,6-bisphosphatase, Bacillus type; PRIAM: Fructose-bisphosphatase; SPTR: Putative uncharacterized protein; IMG reference gene:2504108037; PFAM: Firmicute fructose-1,6-bisphosphatase.
     
 0.866
Bcop_2176
Mannose-6-phosphate isomerase, class I; COGs: COG1482 Phosphomannose isomerase; InterPro IPR001250; KEGG: bth:BT_0373 mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type I; PRIAM: Mannose-6-phosphate isomerase; SPTR: Putative uncharacterized protein; TIGRFAM: Mannose-6-phosphate isomerase, type I; IMG reference gene:2504107897; PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I.
     
 0.864
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
     
  0.857
Bcop_0381
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate, the first committing step of glycolysis.
     
  0.857
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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