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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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Assay-based Predictions
experimentally determined
co-expression
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gene co-occurrence
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Bcop_2201COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: bth:BT_0260 acyltransferase family protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504107922; PFAM: Acyltransferase. (181 aa)    
Predicted Functional Partners:
Bcop_2202
COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: bfs:BF2951 putative hydrolase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Putative hydrolase; IMG reference gene:2504107923; PFAM: Carbon-nitrogen hydrolase.
       0.739
Bcop_2200
KEGG: bfs:BF2949 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504107921.
       0.651
Bcop_2203
COGs: COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; InterPro IPR006148:IPR003737; KEGG: bfs:BF2953 glucosamine-6-phosphate deaminase-like protein; PFAM: Glucosamine/galactosamine-6-phosphate isomerase; N-acetylglucosaminyl phosphatidylinositol deacetylase; PRIAM: Glucosamine-6-phosphate deaminase; SPTR: Putative uncharacterized protein; IMG reference gene:2504107924; PFAM: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; GlcNAc-PI de-N-acetylase; TIGRFAM: glucosamine-6-phosphate isomerase.
  
    0.571
Bcop_0535
D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: bfs:BF0370 putative FAD-binding oxidoreductase; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Putative uncharacterized protein; IMG reference gene:2504106209; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain.
     
  0.479
Bcop_1264
Two component transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterProIPR011110:IPR011123:IPR003661:IPR001789:IPR 000005:IPR018060; KEGG: bth:BT_2628 two-component system sensor histidine kinase/response regulator, hybrid ('one-component system'); PFAM: HTH transcriptional regulator, AraC; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Two component regulator three Y; Two component regulator propeller; Signal transduction response regulator, receiver domain; SMART: Helix-turn-helix, AraC type [...]
  
 
 0.447
Bcop_1683
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR011123:IPR003661:IPR003594:IPR001789:IPR 000005:IPR018060; KEGG: bth:BT_3678 two-component system sensor histidine kinase/response regulator, hybrid ('one-component system'); PFAM: ATPase-like, ATP-binding domain; Two component regulator three Y; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; HTH transcriptional regulator, AraC; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgr [...]
  
 
 0.447
Bcop_1986
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661:IPR003594:IPR001789:IPR018060:IPR 011110:IPR011123:IPR000005; KEGG: bth:BT_4663 two-component system sensor histidine kinase/response; PFAM: ATPase-like, ATP-binding domain; Two component regulator three Y; Two component regulator propeller; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; HTH transcriptional regulator, AraC; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, sub [...]
  
 
 0.447
Bcop_2376
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR011110:IPR011123:IPR003594:IPR001789:IPR 000005:IPR018060; KEGG: bfs:BF3155 putative two-component system sensor kinase/response regulator fusion protein; PFAM: Signal transduction response regulator, receiver domain; Two component regulator three Y; Two component regulator propeller; ATPase-like, ATP-binding domain; HTH transcriptional regulator, AraC; SMART: Helix-turn-helix, AraC type, DNA binding domain; Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; SPTR: Two [...]
  
 
 0.447
Bcop_1397
Patatin; COGs: COG1752 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641; KEGG: bfs:BF2341 hypothetical protein; PFAM: Patatin/Phospholipase A2-related; SPTR: Predicted esterase of the alpha-beta hydrolase superfamily; IMG reference gene:2504107106; PFAM: Patatin-like phospholipase.
 
  
  0.435
Bcop_1684
Two component regulator propeller domain protein; COGs: COG3292 periplasmic ligand-binding sensor domain; InterPro IPR011110; KEGG: bvu:BVU_0603 two-component system sensor histidine kinase/response regulator, hybrid; PFAM: Two component regulator propeller; SPTR: Two-component system sensor histidine kinase/response regulator, hybrid; IMG reference gene:2504107400; PFAM: Two component regulator propeller.
  
 
 0.415
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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