Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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Score
Bcop_2249COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: bth:BT_1680 putative NADH dehydrogenase/NAD(P)H nitroreductase; PFAM: Nitroreductase-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504107970; PFAM: Nitroreductase family. (179 aa)    
Predicted Functional Partners:
Bcop_2247
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR010023; KEGG: bth:BT_1677 putative hydrolase; SPTR: Phosphatase, YrbI family; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; IMG reference gene:2504107968; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family.
       0.821
Bcop_2248
Protein of unknown function DUF2520-containing protein; COGs: COG5495 conserved hypothetical protein; InterPro IPR004455:IPR018931; KEGG: bth:BT_1678 hypothetical protein; PFAM: Domain of unknown function DUF2520; NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2504107969; PFAM: Domain of unknown function (DUF2520); NADP oxidoreductase coenzyme F420-dependent.
       0.821
Bcop_2246
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
    0.812
Bcop_2250
KEGG: bfs:BF3126 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504107971.
       0.595
Bcop_0625
CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...]
    
 0.484
Bcop_1425
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: bfr:BF1321 O-succinylbenzoic acid-CoA ligase; PFAM: AMP-dependent synthetase/ligase; SPTR: O-succinylbenzoic acid-CoA ligase; IMG reference gene:2504107134; PFAM: AMP-binding enzyme.
    
   0.472
Bcop_2341
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: bba:Bd0279 long-chain fatty-acid-CoA ligase; PFAM: AMP-dependent synthetase/ligase; SPTR: Coronafacic acid synthetase, ligase component; IMG reference gene:2504108072; PFAM: AMP-binding enzyme.
    
   0.472
Bcop_2253
KEGG: bfs:BF3129 hypothetical protein; SPTR: Putative exported protein; IMG reference gene:2504107974; PFAM: Oxaloacetate decarboxylase, gamma chain.
 
    0.463
Bcop_2221
NADPH-dependent FMN reductase; COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: mru:mru_1609 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: Multimeric flavodoxin WrbA; IMG reference gene:2504107942; PFAM: NADPH-dependent FMN reductase.
 
  
 0.433
Bcop_2251
methylmalonyl-CoA epimerase; InterPro IPR017515:IPR004360; KEGG: bth:BT_1685 lactoylglutathione lyase and related protein; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Putative uncharacterized protein; TIGRFAM: Methylmalonyl-CoA epimerase; IMG reference gene:2504107972; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase.
  
    0.429
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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