| node1 | node2 | node1 annotation | node2 annotation | score |
| Bcop_0625 | Bcop_1425 | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: bfr:BF1321 O-succinylbenzoic acid-CoA ligase; PFAM: AMP-dependent synthetase/ligase; SPTR: O-succinylbenzoic acid-CoA ligase; IMG reference gene:2504107134; PFAM: AMP-binding enzyme. | 0.564 |
| Bcop_0625 | Bcop_2249 | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: bth:BT_1680 putative NADH dehydrogenase/NAD(P)H nitroreductase; PFAM: Nitroreductase-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504107970; PFAM: Nitroreductase family. | 0.484 |
| Bcop_0625 | Bcop_2341 | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: bba:Bd0279 long-chain fatty-acid-CoA ligase; PFAM: AMP-dependent synthetase/ligase; SPTR: Coronafacic acid synthetase, ligase component; IMG reference gene:2504108072; PFAM: AMP-binding enzyme. | 0.564 |
| Bcop_1425 | Bcop_0625 | COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: bfr:BF1321 O-succinylbenzoic acid-CoA ligase; PFAM: AMP-dependent synthetase/ligase; SPTR: O-succinylbenzoic acid-CoA ligase; IMG reference gene:2504107134; PFAM: AMP-binding enzyme. | CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001455:IPR001763; KEGG: bfs:BF0525 putative pyridine nucleotide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504106303; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisati [...] | 0.564 |
| Bcop_1425 | Bcop_2249 | COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: bfr:BF1321 O-succinylbenzoic acid-CoA ligase; PFAM: AMP-dependent synthetase/ligase; SPTR: O-succinylbenzoic acid-CoA ligase; IMG reference gene:2504107134; PFAM: AMP-binding enzyme. | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: bth:BT_1680 putative NADH dehydrogenase/NAD(P)H nitroreductase; PFAM: Nitroreductase-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504107970; PFAM: Nitroreductase family. | 0.472 |
| Bcop_2221 | Bcop_2249 | NADPH-dependent FMN reductase; COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: mru:mru_1609 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: Multimeric flavodoxin WrbA; IMG reference gene:2504107942; PFAM: NADPH-dependent FMN reductase. | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: bth:BT_1680 putative NADH dehydrogenase/NAD(P)H nitroreductase; PFAM: Nitroreductase-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504107970; PFAM: Nitroreductase family. | 0.433 |
| Bcop_2246 | Bcop_2247 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR010023; KEGG: bth:BT_1677 putative hydrolase; SPTR: Phosphatase, YrbI family; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; IMG reference gene:2504107968; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family. | 0.810 |
| Bcop_2246 | Bcop_2248 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Protein of unknown function DUF2520-containing protein; COGs: COG5495 conserved hypothetical protein; InterPro IPR004455:IPR018931; KEGG: bth:BT_1678 hypothetical protein; PFAM: Domain of unknown function DUF2520; NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2504107969; PFAM: Domain of unknown function (DUF2520); NADP oxidoreductase coenzyme F420-dependent. | 0.810 |
| Bcop_2246 | Bcop_2249 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: bth:BT_1680 putative NADH dehydrogenase/NAD(P)H nitroreductase; PFAM: Nitroreductase-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504107970; PFAM: Nitroreductase family. | 0.812 |
| Bcop_2246 | Bcop_2250 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | KEGG: bfs:BF3126 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504107971. | 0.589 |
| Bcop_2246 | Bcop_2251 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | methylmalonyl-CoA epimerase; InterPro IPR017515:IPR004360; KEGG: bth:BT_1685 lactoylglutathione lyase and related protein; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Putative uncharacterized protein; TIGRFAM: Methylmalonyl-CoA epimerase; IMG reference gene:2504107972; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase. | 0.409 |
| Bcop_2247 | Bcop_2246 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR010023; KEGG: bth:BT_1677 putative hydrolase; SPTR: Phosphatase, YrbI family; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; IMG reference gene:2504107968; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family. | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.810 |
| Bcop_2247 | Bcop_2248 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR010023; KEGG: bth:BT_1677 putative hydrolase; SPTR: Phosphatase, YrbI family; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; IMG reference gene:2504107968; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family. | Protein of unknown function DUF2520-containing protein; COGs: COG5495 conserved hypothetical protein; InterPro IPR004455:IPR018931; KEGG: bth:BT_1678 hypothetical protein; PFAM: Domain of unknown function DUF2520; NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2504107969; PFAM: Domain of unknown function (DUF2520); NADP oxidoreductase coenzyme F420-dependent. | 0.821 |
| Bcop_2247 | Bcop_2249 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR010023; KEGG: bth:BT_1677 putative hydrolase; SPTR: Phosphatase, YrbI family; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; IMG reference gene:2504107968; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family. | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: bth:BT_1680 putative NADH dehydrogenase/NAD(P)H nitroreductase; PFAM: Nitroreductase-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504107970; PFAM: Nitroreductase family. | 0.821 |
| Bcop_2247 | Bcop_2250 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR010023; KEGG: bth:BT_1677 putative hydrolase; SPTR: Phosphatase, YrbI family; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; IMG reference gene:2504107968; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family. | KEGG: bfs:BF3126 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504107971. | 0.595 |
| Bcop_2247 | Bcop_2251 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR010023; KEGG: bth:BT_1677 putative hydrolase; SPTR: Phosphatase, YrbI family; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; IMG reference gene:2504107968; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family. | methylmalonyl-CoA epimerase; InterPro IPR017515:IPR004360; KEGG: bth:BT_1685 lactoylglutathione lyase and related protein; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Putative uncharacterized protein; TIGRFAM: Methylmalonyl-CoA epimerase; IMG reference gene:2504107972; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase. | 0.419 |
| Bcop_2248 | Bcop_2246 | Protein of unknown function DUF2520-containing protein; COGs: COG5495 conserved hypothetical protein; InterPro IPR004455:IPR018931; KEGG: bth:BT_1678 hypothetical protein; PFAM: Domain of unknown function DUF2520; NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2504107969; PFAM: Domain of unknown function (DUF2520); NADP oxidoreductase coenzyme F420-dependent. | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.810 |
| Bcop_2248 | Bcop_2247 | Protein of unknown function DUF2520-containing protein; COGs: COG5495 conserved hypothetical protein; InterPro IPR004455:IPR018931; KEGG: bth:BT_1678 hypothetical protein; PFAM: Domain of unknown function DUF2520; NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2504107969; PFAM: Domain of unknown function (DUF2520); NADP oxidoreductase coenzyme F420-dependent. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR010023; KEGG: bth:BT_1677 putative hydrolase; SPTR: Phosphatase, YrbI family; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; IMG reference gene:2504107968; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family. | 0.821 |
| Bcop_2248 | Bcop_2249 | Protein of unknown function DUF2520-containing protein; COGs: COG5495 conserved hypothetical protein; InterPro IPR004455:IPR018931; KEGG: bth:BT_1678 hypothetical protein; PFAM: Domain of unknown function DUF2520; NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2504107969; PFAM: Domain of unknown function (DUF2520); NADP oxidoreductase coenzyme F420-dependent. | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: bth:BT_1680 putative NADH dehydrogenase/NAD(P)H nitroreductase; PFAM: Nitroreductase-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504107970; PFAM: Nitroreductase family. | 0.821 |
| Bcop_2248 | Bcop_2250 | Protein of unknown function DUF2520-containing protein; COGs: COG5495 conserved hypothetical protein; InterPro IPR004455:IPR018931; KEGG: bth:BT_1678 hypothetical protein; PFAM: Domain of unknown function DUF2520; NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2504107969; PFAM: Domain of unknown function (DUF2520); NADP oxidoreductase coenzyme F420-dependent. | KEGG: bfs:BF3126 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504107971. | 0.595 |