STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Cooccurrence
Coexpression
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[Homology]
Score
Bcop_2255Sodium ion-translocating decarboxylase, beta subunit; COGs: COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; InterPro IPR005661; KEGG: bfs:BF3131 putative methylmalonyl-CoA decarboxylase, beta subunit; PFAM: Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; PRIAM: Oxaloacetate decarboxylase; SPTR: Putative uncharacterized protein; TIGRFAM: Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; IMG reference gene:2504107976; PFAM: subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit. (386 aa)    
Predicted Functional Partners:
Bcop_2254
Biotin/lipoyl attachment domain-containing protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR000089; KEGG: bfs:BF3130 putative biotin carboxyl carrier protein; PFAM: Biotin/lipoyl attachment; SPTR: Biotin carboxyl carrier protein; IMG reference gene:2504107975; PFAM: Biotin-requiring enzyme.
 
  
  0.981
Bcop_1156
COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891:IPR000089; KEGG: bfs:BF1955 putative pyruvate carboxylase biotin-containing subunit; PFAM: Pyruvate carboxyltransferase; Biotin/lipoyl attachment; PRIAM: Pyruvate carboxylase; SPTR: Putative pyruvate carboxylase biotin-containing subunit; IMG reference gene:2504106859; PFAM: HMGL-like; Conserved carboxylase domain.
 
 
 0.964
Bcop_2253
KEGG: bfs:BF3129 hypothetical protein; SPTR: Putative exported protein; IMG reference gene:2504107974; PFAM: Oxaloacetate decarboxylase, gamma chain.
 
 
  0.927
Bcop_2386
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: bth:BT_1747 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain; SPTR: Pyru [...]
 
  
 0.902
Bcop_0008
Malic protein NAD-binding; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: bth:BT_1969 malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SMART: Malic enzyme, NAD-binding; SPTR: NADP-dependent malic enzyme; IMG reference gene:2504105663; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
    
 0.900
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
    
 0.880
Bcop_0433
2-oxoacid:acceptor oxidoreductase, alpha subunit; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752:IPR002880:IPR022367; KEGG: bth:BT_2836 2-oxoglutarate synthase subunit KorA; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; PRIAM: 2-oxoglutarate synthase; SPTR: Pyruvate synthase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; IMG reference gene:2504106097; PFAM: domain; Transketolase, C-terminal domain; Pyruvate ferred [...]
    
 0.869
Bcop_1886
Pyruvate, phosphate dikinase; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR010121:IPR002192:IPR008279:IPR000121; KEGG: bfs:BF2567 pyruvate phosphate dikinase; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile domain; PEP-utilising enzyme; PRIAM: Pyruvate, phosphate dikinase; SPTR: Pyruvate,phosphate dikinase; TIGRFAM: Pyruvate, phosphate dikinase; IMG reference gene:2504107602; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding do [...]
   
 
 0.861
Bcop_2184
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880; KEGG: bfs:BF1656 2-ketoisovalerate ferredoxin reductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; PRIAM: 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); SPTR: 2-oxoglutarate oxidoreductase, alpha subunit; IMG reference gene:2504107905; PFAM: domain.
    
  0.860
Bcop_1655
(R)-citramalate synthase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR013709; KEGG: pdi:BDI_2061 2-isopropylmalate synthase LeuA; PFAM: Pyruvate carboxyltransferase; 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; PRIAM: (R)-citramalate synthase; SMART: 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; SPTR: 2-isopropylmalate synthase LeuA; IMG reference gene:2504107371; PFAM: LeuA allosteric (dimerisation) domain; HMGL-like; Belongs to the alpha-IPM synthase/homocitrate synthase family.
     
 0.859
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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