STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Bcop_2268MATE efflux family protein; COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: bfs:BF3055 putative antiporter membrane protein; PFAM: Multi antimicrobial extrusion protein; SPTR: Multidrug efflux transporter, transmembrane MatE family; TIGRFAM: Multi antimicrobial extrusion protein; IMG reference gene:2504107991; PFAM: MatE; TIGRFAM: putative efflux protein, MATE family. (442 aa)    
Predicted Functional Partners:
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
       0.701
folD
Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
    0.617
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
       0.538
Bcop_0944
COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR020828:IPR020829:IPR006424; KEGG: bvu:BVU_3585 glyceraldehyde 3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SMART: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; SPTR: Glyceraldehyde 3-phosphate dehydrogenase; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I; IMG reference gene:250 [...]
   
  
 0.479
Bcop_2271
Capsule synthesis protein, CapA; COGs: COG2843 Putative protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: bth:BT_1608 capsule biosynthesis protein CapA; PFAM: Capsule synthesis protein, CapA; SMART: Capsule synthesis protein, CapA; SPTR: Capsule biosynthesis protein CapA; IMG reference gene:2504107994; PFAM: Bacterial capsule synthesis protein PGA_cap.
       0.451
Bcop_1158
MATE efflux family protein; COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: bfs:BF1960 MatE family transmembrane protein; PFAM: Multi antimicrobial extrusion protein; SPTR: MatE family transmembrane protein; TIGRFAM: Multi antimicrobial extrusion protein; IMG reference gene:2504106861; PFAM: MatE; TIGRFAM: putative efflux protein, MATE family.
  
     0.448
rplR
Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
  
  
 0.409
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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