STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Bcop_2400Sigma54 specific transcriptional regulator, Fis family; COGs: COG3604 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterPro IPR002078:IPR002197:IPR003593; KEGG: bfs:BF0998 putative sigma-54 dependent transcriptional regulator; PFAM: RNA polymerase sigma factor 54, interaction; Helix-turn-helix, Fis-type; SMART: ATPase, AAA+ type, core; SPTR: Putative uncharacterized protein; IMG reference gene:2504108132; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain. (402 aa)    
Predicted Functional Partners:
Bcop_0498
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR007046:IPR007634:IPR000394; KEGG: bfr:BF4361 RNA polymerase sigma-54; PFAM: RNA polymerase sigma factor 54, DNA-binding; RNA polymerase sigma factor 54, core-binding; SPTR: RNA polymerase sigma-54; TIGRFAM: RNA polymerase sigma factor 54; IMG reference gene:2504106165; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
 
  
 0.970
Bcop_1264
Two component transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterProIPR011110:IPR011123:IPR003661:IPR001789:IPR 000005:IPR018060; KEGG: bth:BT_2628 two-component system sensor histidine kinase/response regulator, hybrid ('one-component system'); PFAM: HTH transcriptional regulator, AraC; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Two component regulator three Y; Two component regulator propeller; Signal transduction response regulator, receiver domain; SMART: Helix-turn-helix, AraC type [...]
  
 0.950
Bcop_1683
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR011123:IPR003661:IPR003594:IPR001789:IPR 000005:IPR018060; KEGG: bth:BT_3678 two-component system sensor histidine kinase/response regulator, hybrid ('one-component system'); PFAM: ATPase-like, ATP-binding domain; Two component regulator three Y; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; HTH transcriptional regulator, AraC; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgr [...]
  
 0.950
Bcop_1986
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661:IPR003594:IPR001789:IPR018060:IPR 011110:IPR011123:IPR000005; KEGG: bth:BT_4663 two-component system sensor histidine kinase/response; PFAM: ATPase-like, ATP-binding domain; Two component regulator three Y; Two component regulator propeller; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; HTH transcriptional regulator, AraC; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, sub [...]
  
 0.950
Bcop_2376
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR011110:IPR011123:IPR003594:IPR001789:IPR 000005:IPR018060; KEGG: bfs:BF3155 putative two-component system sensor kinase/response regulator fusion protein; PFAM: Signal transduction response regulator, receiver domain; Two component regulator three Y; Two component regulator propeller; ATPase-like, ATP-binding domain; HTH transcriptional regulator, AraC; SMART: Helix-turn-helix, AraC type, DNA binding domain; Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; SPTR: Two [...]
  
 0.950
Bcop_1684
Two component regulator propeller domain protein; COGs: COG3292 periplasmic ligand-binding sensor domain; InterPro IPR011110; KEGG: bvu:BVU_0603 two-component system sensor histidine kinase/response regulator, hybrid; PFAM: Two component regulator propeller; SPTR: Two-component system sensor histidine kinase/response regulator, hybrid; IMG reference gene:2504107400; PFAM: Two component regulator propeller.
  
 0.916
Bcop_2007
Histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR019734:IPR003594; KEGG: bfs:BF2281 putative two component system sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; Tetratricopeptide repeat; SPTR: Putative uncharacterized protein; IMG reference gene:2504107726; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
   
 0.887
Bcop_2386
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: bth:BT_1747 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain; SPTR: Pyru [...]
    
 0.885
Bcop_1612
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789; KEGG: bvu:BVU_1552 two-component system sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SPTR: Tetracycline resistance element regulator Rt [...]
   
 0.865
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.861
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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